Arvinas to Present at the 17th Annual Needham Healthcare Conference

On March 20, 2018 Arvinas LLC, a private biotechnology company creating a new class of drugs based on protein degradation, reported that John Houston, Ph.D., President and Chief Executive Officer of Arvinas, will present a company overview at the 17th Annual Needham Healthcare Conference on Tuesday, March 27, 2018 at 8:30 a.m. ET in New York, NY (Press release, Arvinas, MAR 19, 2018, View Source [SID1234524882]).

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OncoMed Announces Appointment of John Lewicki, PhD, as President, Chief Executive Officer and a member of the Board of Directors

On March 19, 2018 OncoMed Pharmaceuticals, Inc. (NASDAQ:OMED), a clinical-stage biopharmaceutical company focused on discovering and developing novel anti-cancer therapeutics, reported the appointment of Dr. John Lewicki as President and Chief Executive Officer of OncoMed, effective immediately. Dr. Lewicki was also appointed to the company’s Board of Directors (Press release, OncoMed, MAR 19, 2018, View Source [SID1234524877]).

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"John has been a key member of the OncoMed leadership team since the formation of the company, and he has guided our science to the discovery and development of all of our therapeutic candidates," said Perry Karsen, Executive Chairman of OncoMed’s Board of Directors. "The OncoMed Board of Directors and I are fully confident that John’s leadership as President and Chief Executive Officer will help ensure the company maximizes the value of our therapeutic candidates for cancer patients and our shareholders. We look forward to working closely with John and the entire OncoMed team to have a positive impact on cancer patients."

"I am honored to now serve as OncoMed’s President, Chief Executive Officer and a member of the Board, and to be given the opportunity to lead the company at this pivotal time as we advance our lead therapeutic candidates, anti-TIGIT, GITRL-Fc, and navicixizumab, through clinical development," said Dr. Lewicki. "I am very excited to continue working with my OncoMed colleagues in my new role as we strive to discover and develop cancer therapeutics for patients in need, while creating value for our shareholders."

Most recently, Dr. Lewicki was named the company’s President in January 2018. Dr. Lewicki joined OncoMed in 2004 as the company’s Senior Vice President of Research and Development before subsequently assuming additional leadership roles within Research and Development. Dr. Lewicki was named the company’s Executive Vice President and Chief Scientific Officer in 2009 and then became Executive Vice President, Research and Development in 2016. Earlier in his career, Dr. Lewicki served in various capacities at Scios, Inc., where as Vice President of Research, he managed the company’s organization across diverse therapeutic areas. Among his achievements while at Scios was the co-discovery of human B-type natriuretic peptide and its development as an FDA-approved treatment for acute congestive heart failure.

LabCorp Completes Acquisition of Covance

On March 19, 2018 Laboratory Corporation of America Holdings (LabCorp) (NYSE: LH) reported the completion of its acquisition of Covance Inc., following its entry into a definitive purchase agreement on November 2, 2014 (Press release, LabCorp, MAR 19, 2018, View Source [SID1234524829]). At closing, the purchase consideration was valued at $107.19 per Covance share, consisting of $75.76 in cash and 0.2686 LabCorp shares for each Covance share, or an equity value of approximately $6.2 billion and an enterprise value of approximately $5.7 billion. This combination creates the world’s leading healthcare diagnostics company, providing comprehensive clinical laboratory services and end-to-end solutions for drug and diagnostics development and commercialization.

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"We are excited to bring two industry leaders together to provide a unique and complete set of services that will benefit all healthcare stakeholders," said David P. King, Chairman and Chief Executive Officer of LabCorp. "Our complementary services and capabilities will enable us to pursue multiple strategic opportunities in both the clinical laboratory and drug development businesses. Through this combination, we expect to achieve significant revenue growth and generate strong cash flows, allowing us to further invest in our business, fund future expansion and create value for our shareholders."

Mr. King added, "I have worked closely with the Covance team since November and am impressed with their talents and scientific expertise. Combined with the enormously talented people of LabCorp, we will employ our capabilities to enhance drug development, diagnostic services and the delivery of healthcare to better address the system’s demand for improved outcomes at lower costs."

The combined company’s headquarters are located in Burlington, North Carolina. Covance Drug Development will continue to operate under the Covance name, with its headquarters in Princeton, New Jersey.

The closing of the transaction follows the receipt of all necessary regulatory requirements and approval of the transaction by Covance shareholders on February 18, 2015. With the closing of the transaction, Covance common stock will cease trading and will no longer be listed on the NYSE.

Linnaeus Therapeutics Awarded $300,000 Phase 1 STTR by National Cancer Institute

On March 16, 2018 Linnaeus Therapeutics, Inc. ("Linnaeus"), a privately held biopharmaceutical company focused on the development and commercialization of novel, small molecule oncology therapeutics, reported it has been awarded a Phase 1 Small Business Technology Transfer ("STTR") Award by the National Cancer Institute ("NCI") of the National Institute for Health ("NIH") (Press release, Linnaeus Therapeutics, MAR 16, 2018, View Source [SID1234539505]).

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The $300,000 award was granted to Linnaeus in collaboration with one of its scientific cofounders, Todd Ridky, M.D., Ph.D., Assistant Professor of Dermatology at the University of Pennsylvania Perelman School of Medicine, after a highly competitive peer review process. The award will help fund the early development of its lead compound, LNS8801, which targets a G protein-coupled receptor, known as GPER, for the treatment of various cancers.

"This award provides a strong peer-reviewed validation of the core science that is the basis of LNS8801 and its target GPER," said Patrick Mooney, M.D., chief executive officer of Linnaeus. "This money will allow us to further develop GPER agonists as a potentially safe and effective therapeutic for the treatment of various cancers, including melanoma, pancreas, lung and colon cancers, among other. We plan to aggressively develop GPER agonists, and we hope to continue our relationship with NCI over the long term."

10-Q – Quarterly report [Sections 13 or 15(d)]

Generex has filed a 10-Q – Quarterly report [Sections 13 or 15(d)] with the U.S. Securities and Exchange Commission .

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