CytomX to Present at the Jefferies 2018 Healthcare Conference

On May 31, 2018 CytomX Therapeutics, Inc. (Nasdaq:CTMX), a clinical-stage oncology-focused biopharmaceutical company pioneering a novel class of investigational antibody therapeutics based on our Probody therapeutic technology platform, reported it will present at the Jefferies 2018 Healthcare Conference. Sean McCarthy, D.Phil., president and chief executive officer will deliver a corporate overview on June 7, 2018, at 2:00 p.m. ET (Press release, CytomX Therapeutics, MAY 31, 2018, View Source [SID1234527014]).

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A live audio webcast of the presentation will be available through the Investors and News section of CytomX’s website. An archived replay will be available for 90 days following the event.

TapImmune to Present at the Jefferies 2018 Global Healthcare Conference

On May 31, 2018 TapImmune Inc. (NASDAQ: TPIV), a clinical-stage immuno-oncology company, reported that its President and CEO, Peter L. Hoang, will present at the Jefferies 2018 Global Healthcare Conference taking place June 5-8, 2018, in New York City (Press release, TapImmune, MAY 31, 2018, View Source [SID1234527013]).

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TapImmune Company Presentation
Date: Thursday, June 7, 2018
Time: 3:30 PM ET

An audio webcast will be accessible via the News and Events section of the TapImmune website: View Source An archive of the audio will remain available for 90 days following the presentation.

Sarah Cannon to Present Latest Cancer Research Insights at 2018 American Society of Clinical Oncology’s Annual Meeting

On May 31, 2018 Sarah Cannon reported that it will present its latest cancer research insights through more than 85 presentations at the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper)’s (ASCO) (Free ASCO Whitepaper) Annual Meeting (Press release, Sarah Cannon Research Institute, MAY 31, 2018, View Source [SID1234527012]). Hosted in Chicago, from June 1-5, 2018, the ASCO (Free ASCO Whitepaper) Annual Meeting is bringing together global oncology leaders to discuss "Delivering Discoveries: Expanding The Reach of Precision Medicine." Sarah Cannon experts will participate in a number of presentations and educational sessions focused on personalized medicine and targeted investigational therapies that are transforming the current and future state of cancer treatments.

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"Sarah Cannon’s 25-year history has been highlighted by leading in a number of innovative areas of clinical research," said Howard A. "Skip" Burris, III, MD, President of Clinical Operations and Chief Medical Officer at Sarah Cannon. Dr. Burris will also serve as the ASCO (Free ASCO Whitepaper) President for the 2019-2020 term. "From novel antibodies to targeted biologics, and now advancements in the field of cellular therapies, we are bringing cutting-edge treatments to patients closer to home."

As part of ASCO (Free ASCO Whitepaper)’s Meeting focus, Sarah Cannon’s leaders will participate in the following highlighted sessions:

A presentation with Dr. Burris, who will discuss "Most Patients Should Be Tested" in the education session "Point/Counterpoint: Next Generation Sequencing – Is It Right for Every Patient?" which will take place on June 1 from 1:20-1:40pm in S102.
A "Best of ASCO (Free ASCO Whitepaper)" clinical science symposium titled "A Phase 1 Study of LOXO-292, A Potent And Highly Selective RET Inhibitor, In Patients With RET-Altered Cancers" featuring Sarah Cannon co-authors Todd Bauer, MD, and Melissa Johnson, MD, as part of the session "Tumor Genomics: Finding The Target, Hitting The Target" on June 2 from 8-9:30am in Hall D1.
A poster presentation by Stephanie Graff, MD, titled "Implementation of Breast Cancer Pathway For Genetic Counseling And Testing In Multi-State Health System" as part of the session "Health Services Research, Clinical Informatics, and Quality of Care," on June 2 from 1:15-4:45pm in 6521 Hall A.
A poster presentation by Holli Dilks, PhD, and Andrew McKenzie, PhD, titled "Identifying And Interpreting Actionable Molecular Alterations From Next-Generation Sequencing Results In The Community: A Sarah Cannon Molecular Cancer Conference" on June 2 from 1:15-4:45pm in 6601 Hall A.
A poster session by David Moore, MD, titled "Routine Use of A Modest Next Generation Sequencing Panel Provides Additional Clinically Useful Data Beyond Single Gene Testing In Non-Small Cell Lung Cancer And Is Fit For Purpose As A Clinical Assay: Collated Data From A Single Molecular Diagnostic Laboratory" on June 3 from 8-11:30am in 8540 Hall A.
Additionally, Sarah Cannon investigators are presenting noteworthy studies and insights at ASCO (Free ASCO Whitepaper) with the following presentations:

Dr. Burris’ poster session on "Maintenance Of Health-Related Quality Of Life In Elderly Patients Treated With Ribociclib + Letrozole In MONALEESA-2" taking place on June 2 from 8-11:30am in 1041 Hall A.
A poster session by Erika Hamilton, MD, titled "Results from a Phase I Study of Andecaliximab In Combination With Paclitaxel In Patients With Previously Untreated Metastatic Breast Cancer," on June 2 from 8-11:30am in 1032 Hall A. Dr. Hamilton will also highlight research on "Phase 1 Dose Escalation Of XMT-1522, A Novel HER2-Targeting Antibody-Drug Conjugate, In Patients With HER2-Expressing Breast, Lung And Gastric Tumors" in a poster session on June 4 from 8-11:30am in 2546 Hall A.
A poster session with Kent Shih, MD, on "Dianhydrogalactitol In Bevacizumab-Refractory GBM: Further Analysis Of A Phase 1-2 Trial," on June 2 from 1:15-4:45pm in 2061 Hall A.
A poster discussion by Dr. Bauer titled "A Phase 1 Study of MDM2 Inhibitor DS-3032b In Patients With Well/De-Differentiated Liposarcoma, Solid Tumors And Lymphomas" on June 2 from 3-4:15pm in S404.
A poster session by Dr. Johnson on "First In Human Phase 1/2a Study of PEN-221 Somatostatin Analog (SSA)-DM1 Conjugate For Patients With Advanced Neuroendocrine Tumor Or Small Cell Lung Cancer: Phase 1 Results" on June 3 from 8-11:30am in 4097 Hall A. Dr. Johnson will also present a poster on "A Phase I, Open-Label, Multicenter Dose Escalation Study To Assess The Safety, Tolerability, And Pharmacokinetics Of AZD2811 Nanoparticle In Patients With Advanced Solid Tumors" on June 4 from 8-11:30am in 2592 Hall A.
An education session with David Spigel, MD, on "Reimbursement And Payment Of Multiplex Testing In The United States" taking place on June 3 from10:15-10:30am in S100a.
An education session with Dr. Graff on "How Close Is Too Close: Navigating Difficult Situations" as part of the session titled, "When Cancer Hits Close to Home: Treating Colleagues and Loved Ones" on June 4 from 8:30-8:45am in S504.
A poster session by Judy Wang, MD, titled "Interim Results From A Phase 1 Trial Of SL-801, A Novel XPO-1 Inhibitor, In Patients With Advanced Solid Tumors" on June 4 from 8-11:30am in 2560 Hall A.
A poster session by Manish Patel, MD, titled "A Phase 1b Dose-Escalation Study Of Prexasertib, A Checkpoint Kinase 1 (CHK1) Inhibitor, In Combination With Cisplatin In Patients With Advanced Cancer" on June 4 from 8-11:30am in 2579 Hall A.
A poster session by Kathleen Moore, MD, on "Phase 1/2 Open-Label, Multiple Ascending Dose Trial of AGEN2034, An Anti-PD-1 Monoclonal Antibody, In Advanced Solid Malignancies: Results Of Dose Escalation" on June 4 from 8-11:30am in 3086 Hall A.
For a full listing of all presentations authored by Sarah Cannon investigators, visit sarahcannon.com/asco.

Additional Sarah Cannon leaders are co-authors on research presented at the conference, including:

Bertrand Marquess Anz, Raid Aljumaily, MD, Hendrik-Tobias Arkenau, MD, PhD, FRCP, Edward Arrowsmith, MD, Johanna Bendell, MD, Jesus Berdeja, MD, Brook Blackmore, Simon Chowdhury, MA, MRCP, PhD, Mick Correll, Brooke Daniel, MD, Davey Daniel, MD, William Bruce Donnellan, MD, Crystal Dugger, James Essell, MD, Gerald Falchook, MD, MS, Gustavo Fonseca, MD, FACP, Ian Flinn, MD, PhD, Troy Gifford, Lowell Hart, MD, Derek Weldon Holland, MD, Suzanne Jones, PharmD, Darrell Johnson, MD, Sylvia Lynne Krueger, MD, Dax Kurbegov, MD, Andrew Mackenzie, PhD, Michael Maris, MD, Jeffrey Matous, MD, Carmen Murias, MD, Benjamin Rolland Nadeau, MD, Michael Stipanov, MD, DK Strickland, MD, An Tran, MD, Kimberly Tucker, and Denise Yardley, MD.

The researchers represent Sarah Cannon’s global network of strategic sites:

Colorado Blood Cancer Institute, Sarah Cannon Research Institute at Florida Cancer Specialists, Sarah Cannon Research Institute at HCA Midwest Health (Kansas City), Sarah Cannon Research Institute at HealthONE (Denver), Sarah Cannon Research Institute at Tennessee Oncology, , Sarah Cannon Research Institute – United Kingdom, and The Stephenson Cancer Center at the University of Oklahoma

Bicycle Therapeutics and Cancer Research UK Announce Presentation at 2018 American Society of Clinical Oncology Meeting

On May 31, 2018 Cancer Research UK and Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle) product platform, reported a poster presentation at the 2018 Annual Meeting of the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) held from June 1 – June 5, 2018 in Chicago, Ill (Press release, Bicycle Therapeutics, 31 31, 2018, View Source [SID1234527010]). The poster describes their ongoing phase I/IIa clinical trial of BT1718 in patients with advanced solid tumours, which is the first clinical study of a bicyclic peptide.

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Details of the presentation, which will be given by Dr. Udai Banerji, Principal Investigator for the Phase I trial, are as follows:

A Cancer Research UK phase I/IIa trial of BT1718 (a first in class Bicycle Drug Conjugate) given intravenously in patients with advanced solid tumours
Session Title: Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics
Time: June 4, 2018, 8:00 – 11:30 a.m. CT

ABOUT BT1718
BT1718 is a first-in-class Bicycle Toxin Conjugate being developed by Bicycle Therapeutics that targets Membrane Type 1 Matrix Metalloproteinase (MT1-MMP), also known as MMP-14. This target has an established role in cell invasion and metastasis, is linked to poor outcomes and is over expressed in many solid tumours. In preclinical models, BT1718 has demonstrated promising target-dependent efficacy and only a subset of the toxicities typically associated with other highly potent cancer treatments.

Cancer Research UK’s Centre for Drug Development (CDD) is sponsoring a Phase I/IIa study of BT1718 that started in February 2018 with patients currently progressing through dose escalation cohorts. The trial is co-managed by Cancer Research UK and Bicycle Therapeutics. Under the terms of the agreement, Bicycle retains the right to further advance the BT1718 program, at which point an undisclosed payment split between cash and equity, success-based milestones and royalty payments would be made to Cancer Research UK.

Xencor to Present at Upcoming Investor Conferences

On May 31, 2018 Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, reported that company management will present at two upcoming conferences (Press release, Xencor, MAY 31, 2018, View Source [SID1234527009]):

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Jefferies 2018 Healthcare Conference
Date: Thursday, June 7, 2018
Time: 1:30 p.m. ET
Location: New York, NY

JMP Securities Life Sciences Conference
Date: Wednesday, June 20, 2018
Time: 1:30 p.m. ET
Location: New York, NY

Live webcasts of both events will be available under "Events & Presentations" in the Investors section of the Company’s website located at View Source A replay of the presentations will be posted on the Xencor website approximately one hour after the live events and will be available for 90 days following the presentations.