On August 27, 2018 Linnaeus Therapeutics, Inc. ("Linnaeus"), a privately held biopharmaceutical company focused on the development and commercialization of novel, small molecule oncology therapeutics, reported that it has closed a $4.4 million series A financing (Press release, Linnaeus Therapeutics, AUG 27, 2018, View Source [SID1234539508]). Kairos Ventures, of Beverly Hills, California, led the financing with significant participation from the University of Pennsylvania, Linnaeus CEO, Patrick Mooney, and Linnaeus SVP, R&D, Tina Garyantes.

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The company intends to use the proceeds from the financing to advance its lead compound, LNS8801, through its nonclinical development with the goal of filing an Investigational New Drug Application ("IND") in the summer of 2019.

As a result of the financing, Nikos Iatropoulos, a Kairos Ventures’ partner and its chief operating officer, will be joining the company’s board of directors.

"We are very excited to have Kairos as the lead investor in our Series A round. They are the premier early-stage life science and technology investor, and they will bring tremendous value as will build Linnaeus," said Patrick Mooney, M.D., chief executive officer of Linnaeus. "With the series A proceeds we look forward to advancing LNS8801 toward an IND filing and phase 1 and 2 clinical studies that should begin in 2019."

On August 27, 2018 Biotheus Inc. reported that it will develop innovative biomedical projects valued at 800 million yuan ($125 million) in Zhuhai with revenue expected to exceed 3 billion yuan ($469 million) once production begins (Press release, Biotheus, AUG 27, 2018, View Source [SID1234533245]).

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The development will be a joint effort with the Zhuhai National Hi-Tech Industrial Development Zone (Tangjiawan) Administrative Committee as stipulated in a cooperation agreement signed on Aug 23.

Biotheus is a specialized researcher of brand-new biomedicine in line with advanced international standards. Established this March in the Technological Innovation Coast, it covers 4,500 sq m (1.1 acres).

The company will research and develop a new generation of monoclonal antibodies, recombinant proteins, and peptide biopharmaceuticals. The partnership deal covers six projects seeking first-class bio drugs, including four targeting improvements in tumor immunotherapy and two looking into metabolic disease treatment.

The projects are to be implemented by a professional team with extensive experience in R&D, industrialization, and management in the biomedicine sector. Chief among them are Liu Xiaolin, CEO of the company, who was previously the senior vice president at Innovent Biologics, and Lyu Qiang, chairman of the company and an expert listed in the national Thousand Talent Program.

Researchers at Prometheus Bio-technology

Staffers involved have participated in more than 40 R&D projects, and the products resulting from their efforts now reap $20 billion in annual sales, according to a manager.

Lyu said the company hopes to lead the Pearl River Delta in contract development and manufacturing organization in biomedicine and will promote the growth of related industries.

On August 27, 2018 BioCanCell Ltd. (TASE: ANCN), a clinical-stage biopharmaceutical company focused on the discovery and development of novel therapies to treat cancer, reported that the company is changing its name to Anchiano Therapeutics (Press release, BioCancell Therapeutics, AUG 27, 2018, View Source [SID1234532563]). Anchiano Therapeutics remains publicly traded on the Tel Aviv Stock Exchange under the ticker symbol "ANCN" (formerly "BICL").

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"We have undergone a transformation over the last two years, opening our office in Cambridge, bringing our clinical development team aboard, and preparing our pivotal clinical development program for execution in the US and internationally. Our new name, Anchiano Therapeutics, reflects the next stage in our evolution," said Frank Haluska, M.D., Ph.D., President and Chief Executive Officer of Anchiano Therapeutics. "Anchiano is the birthplace of Leonardo da Vinci. It is our symbolic wellspring of the innovation and artistry in science that lies at the foundation of our commitment to bringing new approaches to the treatment of cancer. The first of these, our experimental gene therapy for early bladder cancer with inodiftagene vixteplasmid, will enter its initial pivotal study, the Codex Trial, later this year."

On August 27, 2018 Delcath Systems, Inc. (OTCQB: DCTH), an interventional oncology company focused on the treatment of primary and metastatic cancers of the liver, reported an abstract from a study conducted in Germany of the use of the Delcath Hepatic CHEMOSAT Delivery System to treat patients with metastatic ocular melanoma with liver metastases, has been accepted for presentation as a poster at the Cardiovascular and Interventional Radiology Society of Europe (CIRSE) annual meeting (Press release, Delcath Systems, AUG 27, 2018, View Source;p=RssLanding&cat=news&id=2364903 [SID1234529755]). The abstract, Survival and Response of Patients with Metastatic Ocular Melanoma after Chemosaturation Percutaneous Hepatic Perfusion, will be presented by M. Zeile, and A. Stang, et al of the Asklepios Barmbek Clinic in Hamburg, Germany.

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The CIRSE 2018 annual meeting will be held in Lisbon, Portugal September 22-25, 2018.

On August 27, 2018 Intellia Therapeutics, Inc. (NASDAQ:NTLA), a leading genome editing company focused on the development of curative therapeutics using CRISPR/Cas9 technology, reported that it will participate in the following upcoming healthcare conferences in September (Press release, Intellia Therapeutics, AUG 27, 2018, View Source [SID1234529472]):

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Tuesday, September 4, 2018
B. Riley FBR Healthcare Conference
Panel: A Beginner’s Guide to Gene Therapy
Location: New York, NY
Time: 12:50pm ET

Wednesday, September 5, 2018
Citi Biotech Conference
Panel: Gene Editing
Location: Boston, Massachusetts
Time: 1:15pm ET

Thursday, September 6, 2018
Wells Fargo Healthcare Conference
Location: Boston, Massachusetts
Time: 3:05pm ET

Thursday, September 27, 2018
Jefferies Gene Therapy Summit
Location: New York, NY

A live webcast of Intellia’s participation on the panel at the Citi Biotech Conference and presentation at the Wells Fargo Healthcare Conference will be accessible through the Events and Presentations page of the Investor Relations section of the company’s website at www.intelliatx.com. To access the webcasts, please log on to the Intellia website approximately 15 minutes prior to the start time to ensure adequate time for any software downloads that may be required. A replay of the webcasts will be available on Intellia’s website for approximately 14 days following each conference.