OncoSec to Present at Cantor Fitzgerald Global Healthcare Conference

On September 25, 2018 OncoSec Medical Incorporated (OncoSec) (NASDAQ: ONCS), a company developing intratumoral cancer immunotherapies, reported that Daniel J. O’Connor, President and Chief Executive Officer of OncoSec, will present a corporate overview at the Cantor Fitzgerald Global Healthcare Conference on Monday, October 1, 2018 at 4:05 p.m. ET in New York City (Press release, OncoSec Medical, SEP 25, 2018, View Source [SID1234529636]).

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A live audio webcast of the presentation will be available on the Investors section of OncoSec’s website at ir.oncosec.com, where it will be archived for approximately 30 days.

LabCorp to Announce Third Quarter Financial Results on October 24, 2018

On September 25, 2018 LabCorp (NYSE: LH) reported that it will release its third quarter 2018 financial results before the market opens on Wednesday, October 24, 2018, and then will host a conference call and webcast beginning at 9:00 a.m. EDT to discuss the results (Press release, LabCorp, SEP 25, 2018, View Source;p=RssLanding&cat=news&id=2368816 [SID1234529635]). The earnings release and accompanying financial information will be posted on the LabCorp Investor Relations website.

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Interested parties can access the conference call in listen-only mode by dialing 844-634-1444 within the U.S. and Canada, or 1-615-247-0253 internationally, using the passcode 7398818. In addition, a real-time webcast of the conference call will be available on the LabCorp Investor Relations website.

An audio replay of the conference call will be available from 1:00 p.m. EDT on October 24, 2018, until 11:30 a.m. EDT on November 7, 2018, by dialing 855-859-2056 within the U.S. and Canada, or 1-404-537-3406 internationally, using the passcode 7398818. The webcast of the conference call will be archived and accessible through October 18, 2019, on the LabCorp Investor Relations website.

Xencor to Participate in Upcoming Investor Conferences

On September 25, 2018 Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, reported that company management will participate in three upcoming conferences (Press release, Xencor, SEP 25, 2018, View Source [SID1234529623]):

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2018 Cantor Global Healthcare Conference
Date: Tuesday, October 2, 2018
Location: New York, NY
Presentation Time: 10:55 a.m. ET

Leerink Partners Roundtable Series: Rare Disease & Oncology
Date: Wednesday, October 3, 2018
Location: New York, NY
Presentation Time: 10:00 a.m. ET

BTIG Biotech Conference
Date: Thursday, October 25, 2018
Location: New York, NY
Management will be available for one-on-one meetings.
Live webcasts of both the 2018 Cantor Global Healthcare Conference and the Leerink Partners Roundtable Series: Rare Disease & Oncology presentations will be available under "Events & Presentations" in the Investors section of the Company’s website located at View Source A replay of the presentations will be posted on the Xencor website approximately one hour after the live events and will be available for 90 days following the presentations.

NEC Laboratories Europe GmbH, the National Center for Tumor Diseases and Protagen AG collaborate to improve information integration and artificial intelligence for better therapy decisions in Immuno-Oncology

On September 25, 2018 Protagen AG, the National Center for Tumor Diseases (NCT) and NEC Laboratories Europe GmbH have reported a collaboration to improve the in silico prediction of immunotherapy response in malignant melanoma (Press release, Protagen, SEP 25, 2018, View Source [SID1234529620]).

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Cancer immunotherapy, e.g. by Checkpoint inhibitors, offers enormous potential for the treatment of many cancer indications, including melanoma. Although stimulation of the immune system holds great promise for cancer treatment, many challenges remain, including a limited response rate and even resistance in some patients. Also, patients may suffer from severe immune-related adverse events (irAEs), resulting from an overactivated immune response. Both the variable clinical response and irAEs demand predictive models to support patient management.

Through this collaboration, Protagen, NCT and NEC will develop and apply deep machine-learning to explore and establish biomarker models for relevant treatment-associated endpoints such as irAEs, clinical response, and/or survival.

Dr. Saverio Niccolini, General Manager, NEC Laboratories Europe commented: "The field of machine learning and AI has witnessed dramatic progress over the last decade and will soon be a critical component for the analysis of patient data. Extensive biomarker guidance will be required to allocate patients to the most appropriate clinical trial and – after approval of novel treatments – deliver the best therapy to each patient. We would like to be involved in this process and look forward to the collaboration with the NCT and Protagen."

PD Dr. Jessica Hassel from the NCT, stated: "Checkpoint inhibitors offer an enormous potential but also provide some challenges. Building on our initial collaboration with Protagen, we see this project as an opportunity to address the challenges posed by limited response rates and irAEs utilizing machine learning and AI. Although to date its impact remains low, we are convinced that from the molecular characterization of tumors to personalized treatment, machine learning will be increasingly important, hence we look forward to this collaboration."

Dr. Georg Lautscham, Protagen’s CEO, added: "Immunotherapies are a new cornerstone in treating cancer patients. An important challenge is to understand which patients are most likely to respond or suffer from irAEs. Protagen has developed an immuno-profiling approach and machine learning strategies to deal with highly dimensional patient data to address this. We are convinced machine learning efforts will increasingly influence the field, and are excited that NEC and NCT share this view and look forward to advancing this approach together."

Molecular Templates, Inc. Announces Closing of Public Offering of Common Stock and the Full Exercise of the Underwriters’ Option to Purchase Additional Shares

On September 25, 2018 Molecular Templates, Inc. (Nasdaq: MTEM) ("Molecular"), a clinical-stage oncology company focused on the discovery and development of proprietary engineered toxin bodies (ETBs), which are differentiated, targeted, biologic therapeutics for cancer, reported the closing of its underwritten public offering of 9,430,000 shares of its common stock, which includes the exercise in full by the underwriters of their option to purchase 1,230,000 additional shares of common stock, at a price to the public of $5.50 per share (Press release, Molecular Templates, SEP 25, 2018, View Source [SID1234529618]). The gross proceeds to Molecular from the offering, before deducting the underwriting discounts and commissions and estimated offering expenses payable by Molecular, are expected to be approximately $52 million. All of the shares of common stock to be sold in the offering are being sold by Molecular.

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Molecular intends to use the net proceeds from the offering, together with its existing cash and cash equivalents, to fund: its ongoing Phase Ib and Phase II clinical studies and planned additional Phase II clinical studies for MT-3724 in DLBCL; its share of development expenses in its CD38 collaboration with Takeda; its programs targeting HER2 and PD-L1; further preclinical development and drug discovery activities in its other programs and for working capital and general corporate purposes.

Cowen, Evercore ISI and UBS Investment Bank acted as joint book-running managers for the offering. Laidlaw & Company (UK) Ltd. acted as lead manager for the offering. Ladenburg Thalmann acted as financial advisor to Molecular.

The shares are being offered by Molecular pursuant to a shelf registration statement on Form S-3 that was previously filed with the U.S. Securities and Exchange Commission (the "SEC") and declared effective by the SEC. The final prospectus relating to the offering was filed with the SEC, and is available on the SEC’s website located at View Source Copies of the final prospectus supplement and the accompanying prospectus relating to the offering may be obtained by contacting Cowen and Company, LLC, c/o Broadridge Financial Services, 1155 Long Island Avenue, Edgewood, NY 11717, Attention: Prospectus Department, or by telephone at (631) 274-2806; Evercore Group L.L.C., Attention: Equity Capital Markets, 55 East 52nd Street, 36th Floor, New York, NY 10055, by telephone at 888-474-0200, or by email at [email protected]; or UBS Securities LLC, Attention: Prospectus Department, 1285 Avenue of the Americas, New York, NY 10019, by telephone at 1-888-827-7275, or by emailing [email protected].

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities, in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction