AMN Healthcare to Host Second Quarter 2019 Earnings Conference Call on Tuesday, August 6, 2019

On July 11, 2019 AMN Healthcare Services, Inc. (NYSE: AMN), healthcare’s leader and innovator in workforce solutions and staffing services, reported that it will host a conference call to discuss its second quarter 2019 financial results on Tuesday, August 6, 2019 at 5:00 p.m. Eastern Time (Press release, AMN Healthcare Services, JUL 11, 2019, View Source [SID1234537492]). The Company also expects to issue an earnings news release on Tuesday, August 6, 2019 after market close at approximately 4:15 p.m. Eastern Time.

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A live webcast of the call can be accessed through AMN Healthcare’s website at View Source Please log in at least 10 minutes prior to the conference call in order to download the applicable audio software. Interested parties may participate live via telephone by dialing (800) 230-1092 in the U.S. or (612) 288-0329 for international callers. Following the conclusion of the call, a replay of the webcast will be available at the Company’s website. Alternatively, a telephonic replay of the call will be available beginning at 7:30 p.m. Eastern Time on August 6, 2019, and can be accessed until 11:59 p.m. Eastern Time on August 20, 2019 by calling (800) 475-6701 in the U.S. or (320) 365-3844 internationally, with access code 469775.

Gilead Appoints Christi L. Shaw as Chief Executive Officer of Kite

On July 11, 2019 Gilead Sciences, Inc. (NASDAQ: GILD) reported that Christi L. Shaw will join the company as Chief Executive Officer of Kite, a Gilead Company, and will become a member of Gilead’s senior leadership team (Press release, Gilead Sciences, JUL 11, 2019, View Source [SID1234537491]).

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Ms. Shaw is a renowned leader with deep experience providing commercial, financial, strategic, medical and operations leadership across the biopharmaceutical industry. Ms. Shaw currently serves as Senior Vice President of Eli Lilly &. Co., and President of Lilly Bio-Medicines. She also serves as a board member of both Avantor, Inc. and the Biotechnology Industry Organization (BIO), and as an advisor to the Healthcare Businesswomen’s Association.

Prior to joining Lilly, Ms. Shaw most recently served as U.S. Country Head and President of Novartis Corp. and North American Head of Novartis Oncology. She earned a BA in Business Administration from Iowa State University and an MBA from the University of Wisconsin.

"We conducted an extensive search for a new leader at Kite and we believe that Christi’s unique set of skills will allow us to continue to build on our leadership position in cell therapy," said Daniel O’Day, Chairman and Chief Executive Officer of Gilead. "Christi’s vast experience across complex therapeutic areas, and particularly in oncology, will serve Kite very well. She is clearly a leader who will bring teams and individuals together and I am confident she will build upon the entrepreneurial spirit at Kite as we seek to help more people with cancer around the world."

"Kite’s vision of transformational drug development – and of curing cancer – is one that I am extremely passionate about," said Ms. Shaw. "I look forward to working with the many talented individuals in this organization, as we change the way cancer is treated and bring forward important, life-saving therapies."

CURE Media Group Adds the Healing NET Foundation to Its Strategic Alliance Partnership Program

On July 11, 2019 CURE Media Group, which reaches over 1 million patients, survivors and caregivers across an industry-leading multimedia platform devoted solely to cancer updates and research, reported the addition of the Healing NET Foundation to its Strategic Alliance Partnership (SAP) program (Press release, CURE, JUL 11, 2019, View Source [SID1234537490]).

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"We are excited to be partnering with the Healing NET Foundation," said Michael J. Hennessy Jr., president of MJH Associates, Inc., parent company of CURE Media Group. "This foundation is helping patients across the nation with neuroendocrine cancer by bringing together multiple stakeholders."

The Healing NET Foundation is a nonprofit that strives to optimize the care of those with neuroendocrine cancer through the education of and collaboration among physicians, health care providers, patients and caregivers. Neuroendocrine tumors (NETs) are an unusual set of malignancies that are difficult to diagnose and cause many unusual symptoms that often lead to an improper or significantly delayed diagnosis. The Healing NET’s focus is advocating for a new standard of care that patients with NETs deserve.

"Collaboration is a core value of the Healing NET Foundation as we seek to foster a better understanding of neuroendocrine (NET) cancer in the medical communities and help patients connect with their physicians in ways that achieve top care. CURE Media Group and their Strategic Alliance Partnership aligns perfectly with our values and we are delighted to work with them to create more awareness and education about NET cancer," said Cindy Lovelace, co-founder and executive director of the Healing NET Foundation.

The SAP program builds a community of advocacy groups, medical associations and medical institutions to foster collaboration and an open exchange of information among trusted peers for the ultimate benefit of patients and their families. As part of this joint effort, CURE Media Group will work with the Healing NET Foundation to get the word out about NET cancers. Cure recently covered the Healing NET’s 2019 Summit in Nashville, Tennessee.

For more information about CURE Media Group’s SAP program, click here.

For more information about the Healing NET Foundation, click here.

About CURE Media Group

CURE Media Group is the leading resource for cancer updates, research and education. It combines a full suite of media products, including its industry-leading website, CUREtoday.com; innovative video programs, such as "CURE Connections"; a series of widely attended live events; and CURE magazine, which reaches over 1 million readers, as well as the dynamic website for oncology nurses, OncNursingNews.com, and its companion publication, Oncology Nursing News. CURE Media Group is part of the Cranbury, New Jersey-based MJH Associates, Inc., family of businesses, which includes the acclaimed OncLive platform of resources for the practicing oncologist. For more information, visit View Source and View Source

Elicio Therapeutics Co-founder, Darrell Irvine, Co-authors Research Published in Science Demonstrating Novel AMP-CAR-T Approach to Enhance CAR-T Function in Solid Tumor Cancers

On July 11, 2019 Elicio Therapeutics, a next generation immuno-oncology company, engineering therapies for cancer killing immune responses, reported that studies of its Amphiphile platform in combination with CAR-T therapy (AMP-CAR-T) have shown that activation of CAR-T cells in the lymphatic system gives massive CAR-T cell expansion, and significant functional improvements including enhanced CAR-T cell infiltration of solid tumors, increased anti-tumor cytolytic potential, and improved cytokine response (Press release, Elicio Therapeutics, JUL 11, 2019, View Source [SID1234537489]). The research, conducted in the labs of Elicio co-founder, Darrell Irvine, at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology, will be in the July 12th issue of the journal Science, in a paper entitled "Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor." [1]

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Through precise targeting and delivery directly to the lymphatic system, Elicio is engineering potent Amphiphile immunotherapies including cell therapy activators, immunomodulators, and vaccines for an array of aggressive cancers. The Amphiphile approach is based on the ground-breaking work of Darrell Irvine, PhD., Professor of Biological Engineering and Materials Sciences and Howard Hughes Investigator at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology. The company is currently utilizing the study findings in its AMP-CAR-T platform to develop therapeutic interventions that activate and amplify CAR-T therapy to combat an array of cancers including solid tumors. In addition to enhancing the magnitude and functionality of co-administered CAR-T cells, the published data further shows that the combination of CAR-T with AMP-CAR-T activators leads to the potent induction of natural immune responses thought to be critical for improving activity in solid tumors, enabling prolonged survival and durable cures where CAR-T alone has no effect. Elicio is developing the AMP-CAR-T platform for combination with CAR-T cell therapies in a variety of settings including those targeting CD19, BCMA, and several solid tumor indications.

"CAR-Ts show great promise but historically they’ve had issues with durability of response and efficacy beyond hematologic cancers, which we hypothesized could be due to the lack of a means to properly stimulate these cells in vivo," said Darrell Irvine, Elicio co-founder, senior scientific advisor, and a supporting author. "What we saw in this study is that by activating CAR-T cells through their chimeric receptor in the native micro-environment of lymph nodes, it’s possible to enhance CAR-T treatment of solid tumors across cancer types."

"We believe that Elicio’s AMP-CAR-T platform has the potential to solve many of the major obstacles CAR-T therapy is facing by activating CAR-T cells in the lymph nodes to amplify immune responses which could lead to durable cures for aggressive, liquid and solid tumors," said Julian Adams, Ph.D., board chair, Elicio. "Elicio is developing a pipeline of AMP-CAR-T activators which when administered with CAR-T cells, or other CAR-engineered immune cells, will amplify their function for patients, creating a more powerful and lasting immune response."

About the AMP-CAR-T platform
The Elicio Amphiphile platform enables precise targeting and delivery of immunogens directly to the lymphatic system, the "brain center" of the immune response, to significantly amplify and enhance the body’s own system of defenses to defeat cancer, and stop its recurrence. When combined with CAR-T therapy, AMP-CAR-T activators specifically designed to bind to the CAR receptor are presented on the cell surface of immune cells in the lymph nodes. CAR-T cells passing through the lymph nodes en route to the tumor see these AMP-CAR-T activators on the surface of specialized antigen presenting cells (APCs), which then deliver potent activating signals to T cells to coordinate their expansion, development of anti-tumor functions, and mobilization against tumors. This strategy is highly flexible for universal application with any CAR-T therapy without the need for re-engineering of the CAR-T cell design.

Median Technologies Announces Preliminary H1 2019 Unaudited Financial Results

On July 11, 2019 Median Technologies, The Imaging Phenomics Company (Paris: ALMDT), reported preliminary and unaudited financial results for the first half of 2019 (Press release, MEDIAN Technologies, JUL 11, 2019, View Source [SID1234537488]).

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For the first half of 2019, Median Technologies’ revenues reached €4m, an increase of 19.6% compared to the first half of 2018 (€3.4m). Company revenues were entirely generated by the iCRO1 business; the iBiopsy business unit is not generating revenues at this stage, as it currently only includes Research and Development activities.

As of June 30, 2019, net new booking totaled €11m and contributed to an order backlog of €30.7m, a €7m increase compared to the backlog as of December 31, 2018. During the first half of 2019, new business growth for the iCRO was strengthened by increased business in China, along with several new Phase III contracts signed with Top 5 pharma sponsors in the US and in Europe. H1 2019 business activity validates the reorganization and strategic refocus, which was put into action in 2018. The iCRO order booking enables Median to be confident about 2019 revenues and beyond. As of June 30, 2019, the iCRO business unit is operationally at its break-even point.

As of June 30, 2019, the Company’s cash and cash equivalents are expected to be approximatively €7.9m. This amount doesn’t include the €1.5m Research Tax Credit payment, which will occur during the second semester. The burn rate was significantly reduced in H1 2019 and reached €4.8m, compared to €9.8m during the same period in 2018. In the second half of 2019, the company’s cash should be increased by the release of the first €15m tranche of the European Investment Bank (EIB) financing loan for which negotiations are now in the final stages. As a reminder, the loan will enable Median Technologies to accelerate its investment in the iBiopsy imaging phenomics platform innovation program for the coming years. The ongoing negotiations for this loan have been published on May 15th, 2019.

During the first half of the year, along with Dr. Nozha Boujemaa taking office as Median’s Chief Science and Innovation Officer, Median has continued its R&D investments in iBiopsy, the imaging phenomics platform. The iBiopsy Business Unit has been reorganized and its scientific team notably strengthened, with new talents and expertise in Artificial Intelligence and Data Sciences. These changes consolidate Median’s leadership in the field of imaging phenomics. In parallel, Median’s iCRO Business pursued development in China with a China-based structure to run projects and operations locally, leading to a significant increase of order booking in the first half of the year. Regarding the US and EU markets, first semester booking exceeded the booking forecasts for the full 2019.

"During the semester, we harvested the first results of the reorganization and strategic refocus we conducted in 2018," said Fredrik Brag, co-founder and CEO of Median Technologies. "Our current results go beyond our expectations for the semester. The iCRO Business Unit is already break-even operationally, which was initially expected by the end of 2019 only. With new recruitments in the iBiopsy team, we master the most advanced AI and data science technologies which allows us to move forward quickly and increase our technological differentiators. We expect this positive momentum to continue during the second part of the year", he added.

The Company expects to announce Half Year 2019 financial results on October 3, 2019, after market close.

The preliminary results set forth above are based on management’s initial review of the Company’s operations for the year ended December 31, 2018 and are subject to revision based upon the Company’s year-end closing procedures and upon the completion and external audit of the Company’s year-end financial statements. Actual results may differ materially from these preliminary results as a result of the completion of year-end closing procedures, final adjustments and other developments arising between now and the time that the Company’s financial results are finalized, and such changes could be material. In addition, these preliminary results are not a comprehensive statement of the Company’s financial results for the fourth quarter or full year ended December 31, 2018, should not be viewed as a substitute for full, audited financial statements prepared in accordance with generally accepted accounting principles, and are not necessarily indicative of the Company’s results for any future period.