On August 3, 2020 HOOKIPA Pharma Inc. (NASDAQ: HOOK, ‘HOOKIPA’), a company developing a new class of immunotherapeutics targeting infectious diseases and cancers, reported that both the United States Patent and Trademark Office (USPTO) and the European Patent Office (EPO) have issued patents covering HOOKIPA’s proprietary replicating arenavirus technology (TheraT) (Press release, Hookipa Pharma, AUG 3, 2020, View Source [SID1234562683]).

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The patents (US Patent No. 10,722,564 and European Patent No. 3218504) are granted to the University of Geneva. HOOKIPA has exclusively licensed these patents from the University. The patent claims cover current product candidates based on HOOKIPA’s replicating arenavirus platform technology (TheraT), including the Company’s lead oncology product candidates HB-201 and HB-202. These programs are currently in clinical development for the treatment of Human Papillomavirus 16-positive (HPV16+) cancers.

In addition to the replicating arenavirus platform patents, the USPTO recently granted a patent (US Patent No. 10,669,315) specifically related to HOOKIPA’s HB-201 and HB-202 product candidates, which are two different replicating arenavirus-based vectors encoding the same E7/E6 fusion protein. The patent protection for HB-201 and HB-202 conferred by these platform and product-specific patents extends to 2037 in the United States and 2035 in Europe (not taking into account potential Patent Term Extension or Supplementary Protection Certificates).

"The newly issued patents provide general, long-term patent protection for our arenavirus technology and related oncology programs. The combination of broad patents on our arenavirus platform and specific patents on product candidates underpin the commercial potential of the therapies we are developing," said Joern Aldag, HOOKIPA’s Chief Executive Officer.

About Replicating Arenavirus Technology (TheraT)
HOOKIPA’s proprietary and patented replicating arenavirus technology induces powerful immune responses. HOOKIPA’s replicating arenavirus constructs are engineered to be specific for antigens of choice. Arenaviruses have a natural ability to evade neutralization, enabling repeated intravenous delivery.

The replicating arenavirus platform is able to direct more than 50% of a mouse’s T cells to focus on a single target of choice. In various animal models, immunization with HOOKIPA’s replicating arenavirus resulted in elimination of a primary tumor and metastasis and provided long-term protection against a cancer re-challenge months after primary treatment. The Company believes that its arenavirus-based treatments are more potent immunotherapies than alternative therapeutic modalities.

HOOKIPA’s lead oncology programs, HB-201 and HB-202 for the treatment of Hum Papillomavirus 16-positive cancers, are both based on its replicating arenavirus platform.

On August 3, 2020 Spectrum Pharmaceuticals (NasdaqGS: SPPI) a biopharmaceutical company focused on novel and targeted oncology therapies, reported it will host a conference call to discuss the second quarter 2020 financial results and provide a corporate update on Monday, August 10, 2020 at 4:30 p.m. Eastern/1:30 p.m. Pacific (Press release, Spectrum Pharmaceuticals, AUG 3, 2020, View Source [SID1234562682]).

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Conference Call and Webcast:

Monday, August 10, 2020 @ 4:30 p.m. Eastern/1:30 p.m. Pacific
Domestic:

(877) 837-3910, Conference ID# 4093736

International:

(973) 796-5077, Conference ID# 4093736

The conference call will also be available from the Investor Relations section of the company’s website at View Source and will be archived there shortly after the live event.

On August 3, 2020 Syndax Pharmaceuticals, Inc. ("Syndax," the "Company" or "we") (Nasdaq:SNDX), a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies, reported that members of its management team will participate virtually in the BTIG Biotechnology Conference on Monday, August 10, 2020 at 12:00 p.m. ET (Press release, Syndax, AUG 3, 2020, View Source [SID1234562681]).

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A live webcast of the fireside chat can be accessed from the Investor section of the Company’s website at www.syndax.com, where a replay of the event will also be available for a limited time.

On August 3, 2020 ASLAN Pharmaceuticals (Nasdaq: ASLN, TPEx:6497), a clinical-stage immunology and oncology focused biopharmaceutical company developing innovative treatments to transform the lives of patients, reported that Dr Kenneth Kobayashi has been appointed Chief Medical Officer. Dr Kobayashi will be based in California and will be responsible for the global clinical development of ASLAN’s pipeline, including the lead program, ASLAN004, an antibody that blocks the IL-13 receptor, which is being developed for atopic dermatitis (AD) (Press release, ASLAN Pharmaceuticals, AUG 3, 2020, View Source [SID1234562680]).

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Dr Kobayashi has more than 25 years of experience in drug development, clinical practice and regulatory affairs as a Dermatology expert. He most recently served as Senior Medical Director at Dermira, a subsidiary of Eli Lilly, where he was responsible for the development of lebrikizumab, a monoclonal antibody for atopic dermatitis, and supported five Phase 3 registration studies together with preclinical and early clinical development for two novel compounds.

Prior to joining Dermira, Dr Kobayashi was Clinical Development Medical Director at Novartis, in the Immunology, Hepatology and Dermatology Global Development Unit, where he supported the development programs for anti-IL-17C and anti-IgE monoclonal antibodies. He has also held senior and global leadership positions at LEO Pharma and was an Associate Professor, and Chair and Chief of the Division of Dermatology at the University of Ottawa and The Ottawa Hospital.

Dr Carl Firth, Chief Executive Officer, ASLAN Pharmaceuticals, said: "We are pleased to welcome Ken to our team and look forward to working with him as we plan for the late stage development of ASLAN004 in atopic dermatitis. He brings strong industry expertise and relationships from working on other novel biologics being developed for AD as well as his insights as a trained dermatologist. Ken’s appointment is an important step for ASLAN as we build our presence in the US in order to execute our global Phase 2b program in 2021."

Dr Ken Kobayashi, Chief Medical Officer, ASLAN Pharmaceuticals, commented: "I am very excited to join ASLAN and lead the global development of ASLAN004, a program I believe has the potential to be best-in-disease for atopic dermatitis and other indications. I am looking forward to working closely with the team as we prepare for important clinical data readouts later this year from the ongoing multiple ascending dose study in AD and plan our move into additional indications"

Dr Kobayashi completed his residency in Dermatology at the University of British Columbia and was a Chief Resident at the National Defence Medical Centre, Ottawa. He is an Adjunct Professor, Department of Medicine, at the University of Ottawa, and a fellow of the Royal College of Physicians and Surgeons of Canada and the American Academy of Dermatology.

On August 3, 2020 Exact Sciences Corp. (Nasdaq: EXAS) reported that company management will participate in the following conference and invited investors to participate by webcast (Press release, Exact Sciences, AUG 3, 2020, View Source [SID1234562679]).

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Canaccord Genuity Annual Growth Conference
Fireside Chat on Wednesday, August 12, 2020, at 2:30 p.m. EDT
The webcast can be accessed in the investor relations section of Exact Sciences’ website at www.exactsciences.com.