Jon DeVries Named Qlarity Imaging Chief Executive Officer

On September 9, 2020 Life science innovator Paragon Biosciences reported the appointment of Jon T. DeVries as the new chief executive officer of its portfolio company, Qlarity Imaging, a leading artificial intelligence (AI) diagnostics company (Press release, Paragon Biosciences, SEP 9, 2020, View Source [SID1234564899]). A proven leader with in-depth expertise in developing and commercializing medical imaging and AI solutions, Mr. DeVries will be responsible for executing Qlarity Imaging’s mission to advance breast cancer diagnosis through AI-driven technology.

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"Paragon serves as a catalyst and advisor to our portfolio companies to accelerate groundbreaking discoveries that help patients in need. With breast cancer remaining the second leading cause of cancer deaths in women, the need for improved care is undeniable," said Jeff Aronin, founder, chairman and chief executive officer of Paragon Biosciences. "Jon’s impressive background, along with his patient-centered approach and outstanding leadership talents, makes him well-suited to be at the helm of Qlarity Imaging as we seek to help patients live longer, healthier lives."

Mr. DeVries has more than 20 years of experience spearheading the creation and release of innovative cloud-based healthcare initiatives that bring advanced services and technologies to providers and researchers, with the ultimate goal of improving patient care. For example, at Massachusetts General Hospital he launched a Tele3D service that provides any hospital in the country access to three-dimensional (3D) image analytics without incurring the substantial cost of cultivating in-house 3D capabilities. While at IBM, he developed technologies that deliver medical images anywhere at anytime, giving providers a complete view of patients and their histories, and he created software that reduces the time and cost of clinical trials. He also developed the first AI offering at IBM Watson Health Imaging that identifies patients with a potential misdiagnosis to ensure they receive the necessary cardiac care.

Mr. DeVries has earned eight patents in the areas of superconducting electronics, medical imaging and AI. He has served on the HIMSS Interoperability & Standards Committee, a collective effort to improve patient care delivery through the advancement of semantic interoperability and standards-based health IT systems.

"Developing the first diagnostic AI technology to be cleared by the U.S. Food and Drug Administration speaks volumes to Qlarity Imaging’s commitment to innovation in improving breast cancer diagnosis," said Mr. DeVries. "Forward thinking is necessary to make bold scientific breakthroughs, and with Paragon’s support, we are poised to deliver better outcomes for the hundreds of thousands of women who are diagnosed with breast cancer each year."

Mr. DeVries has a Bachelor of Science in Physics from Harvey Mudd College and a Master of Business Administration in Finance and Operations from Columbia University-Columbia Business School.

MilliporeSigma Announces $65 Million Antibody-Drug Conjugate Manufacturing Expansion

On September 9, 2020 MilliporeSigma reported a $65 million expansion of its HPAPI and ADC manufacturing capabilities and capacity at its facility near Madison, Wisconsin (Press release, MilliporeSigma, SEP 9, 2020, View Source [SID1234564898]). This investment will allow large-scale manufacturing of increasingly potent compounds that have the potential to treat cancer. Completion is expected by mid-2022 and should add approximately 50 full-time jobs starting in 2021.

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MilliporeSigma is expanding its ADC manufacturing capabilities. ADCs are an emerging class of medicines designed for high-specificity targeting and destruction of cancer cells, while preserving healthy ones.
"ADCs have posted incredible growth over the last decade and regulatory agencies’ approval in recent years demonstrate their promise as a targeted therapy," said Andrew Bulpin, head of Process Solutions at MilliporeSigma. "With more than 35 years of experience in this space, we have been a frontrunner in the development and manufacturing of biologics, conjugation processes and small molecules. This investment underscores our commitment to working with innovators to bring new treatments to patients quickly and more efficiently."

MilliporeSigma’s new 70,000-square-foot commercial building will be one of the largest dedicated HPAPI manufacturing facilities specifically designed to handle single-digit nanogram occupational exposure limit materials. The facility will incorporate containment areas to produce next-generation linker and payload materials for ADCs. The project is an addition to the company’s Madison campus, which was the first commercial ADC facility in North America designed to handle highly active materials. It will join MilliporeSigma’s established campus in St. Louis, Missouri, which specializes in ADC bio-conjugation, active pharmaceutical ingredients, excipient and adjuvants manufacturing.

ADCs are an emerging class of medicines designed for high-specificity targeting and destruction of cancer cells, while preserving healthy cells. There are now only nine ADCs approved globally. However, the ADC industry is delivering strong growth and is expected to reach $15 billion by 20301.

While ADCs can provide many benefits compared with other therapeutic options, they also present a unique set of challenges. Their development is complex, necessitating stringent containment infrastructure, and their structural exceptionality requires expertise in a number of different technologies for small and large molecules, as well as analytical capabilities. Due to these challenges, more than 70 percent of ADC projects are outsourced to contract development and manufacturing organizations2.

With more than 35 years of experience in the development and manufacturing of small molecules, biologics and ADC technologies, MilliporeSigma offers extensive experience in both clinical and commercial manufacturing. The company’s comprehensive service portfolio combines the steps of drug development and production — from pre-clinical to commercial — from a single source. This consolidation helps reduce risk and streamlines the process of getting therapies to patients faster.

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Aethlon Medical to Present at the H.C. Wainwright 22nd Annual Global Investment Conference

On September 9, 2020 Aethlon Medical, Inc. (Nasdaq: AEMD), a medical device technology company focused on developing products to diagnose and treat life and organ threatening diseases, reported that Timothy C. Rodell, M.D., Chief Executive Officer, is scheduled to provide an overview of the Company on Monday, Sept. 14, at 2:00 p.m. EDT (Press release, Aethlon Medical, SEP 9, 2020, https://www.prnewswire.com/news-releases/aethlon-medical-to-present-at-the-hc-wainwright-22nd-annual-global-investment-conference-301124812.html [SID1234564896])

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Replays of the presentation will be aired live and available for 90 days. The reply can be accessed at View Source and the investor relations section of Aethlon Medical’s website at www.aethlonmedical.com.

Biocept to Present at the H.C. Wainwright Global Investment Virtual Conference on September 14

On September 9, 2020 Biocept, Inc. (Nasdaq: BIOC), a leading commercial provider of molecular diagnostics designed to provide physicians with clinically actionable information to improve the patient outcomes, reported that President and CEO Michael Nall will present at the H.C. Wainwright 22nd Annual Global Investment Conference on Monday, September 14, 2020 at 3:30 p.m. Eastern time (12:30 p.m. Pacific time) (Press release, Biocept, SEP 9, 2020, View Source [SID1234564894]).

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The live presentation can be accessed here and will be archived on the Investor Relations section of the Biocept website.

Viracta Therapeutics to Present at the H.C. Wainwright 22nd Annual Global Investment Conference

On September 9, 2020 Viracta Therapeutics, Inc. (the "Company"), a precision oncology company targeting virus-associated malignancies, reported that Ivor Royston, MD, President and Chief Executive Officer of Viracta, will present a corporate overview at the H.C. Wainwright 22nd Annual Global Investment Conference on Tuesday, September 15, 2020 at 3:00 pm ET (Press release, Viracta Therapeutics, SEP 9, 2020, https://www.prnewswire.com/news-releases/viracta-therapeutics-to-present-at-the-hc-wainwright-22nd-annual-global-investment-conference-301125916.html [SID1234564892]).

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