Entry into a Material Definitive Agreement

On January 2, 2020, Seelos Therapeutics, Inc. (the "Company") reported that it has entered into a stock purchase agreement (the "Stock Purchase Agreement") with Phoenixus AG f/k/a Vyera Pharmaceuticals AG ("Vyera"), pursuant to which the Company issued to Vyera 1,809,845 registered shares of the Company’s common stock (the "Shares") (Filing, 8-K, Apricus Biosciences, JAN 2, 2020, View Source [SID1234552678]). The Company entered into the Stock Purchase Agreement in accordance with that certain Asset Purchase Agreement, dated March 6, 2018, by and between Seelos Corporation, the Company’s wholly owned subsidiary ("STI"), and Vyera, as amended by that certain Amendment to Asset Purchase Agreement, dated as of May 18, 2018, by and between STI and Vyera, as amended by that certain Amendment No. 2 to Asset Purchase Agreement, dated as of December 31, 2018, by and between STI and Vyera, as amended by that certain Amendment No. 3 to Asset Purchase Agreement, dated as of October 15, 2019, by and between STI and Vyera (as amended, the "Asset Purchase Agreement"). Pursuant to the Asset Purchase Agreement, the Company acquired the assets of Vyera related to a product candidate currently referred to as SLS-002 (the "Vyera Assets"), along with liabilities related to the Vyera Assets. As partial consideration for the Vyera Assets, the Company agreed to issue the Shares pursuant to the Stock Purchase Agreement.

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The Shares are being issued pursuant to the Company’s registration statement on Form S-3 (File No. 333-221285), as amended, which was declared effective by the Securities and Exchange Commission (the "SEC") on December 7, 2017, a base prospectus dated December 7, 2017 and a prospectus supplement dated January 2, 2020.

The Stock Purchase Agreement contains customary representations, warranties and covenants made by the Company.

The foregoing description of the Stock Purchase Agreement does not purport to be complete and is qualified in its entirety by reference to the copy of the Stock Purchase Agreement, which is filed as Exhibit 10.1 to this Current Report on Form 8-K. A copy of the opinion of Brownstein Hyatt Farber Schreck, LLP, counsel to the Company, relating to the validity of the Shares is filed with this Current Report on Form 8-K as Exhibit 5.1.

The representations, warranties and covenants contained in the Stock Purchase Agreement were made only for purposes of such agreement and as of specific dates, were solely for the benefit of the parties to the Stock Purchase Agreement, and may be subject to limitations agreed upon by the contracting parties. Accordingly, the Stock Purchase Agreement is incorporated herein by reference only to provide investors with information regarding the terms of the Stock Purchase Agreement, and not to provide investors with any other factual information regarding the Company or its business, and should be read in conjunction with the disclosures in the Company’s periodic reports and other filings with the SEC.

Caris Life Sciences to Present at the 38th Annual J.P. Morgan Healthcare Conference

On January 2, 2020 Caris Life Sciences, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, reported that the company will present at the 38th Annual J.P. Morgan Healthcare Conference on Tuesday, January 14, 2020, at 11:00 a.m. Pacific Time at the Westin St. Francis Hotel, Elizabethan C room, in San Francisco (Press release, Caris Life Sciences, JAN 2, 2020, View Source [SID1234552674]). The company will provide an overview of the business and discuss recent corporate achievements that position it to further extend its leadership in the market. Caris Life Sciences will be represented by David D. Halbert, Chairman, Chief Executive Officer and Founder, Brian J. Brille, Vice Chairman, and David Spetzler, MS, MBA, Ph.D., President and Chief Scientific Officer, and they will take questions from the audience following the presentation.

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Cardinal Health to Webcast Discussion of Second Quarter Results for Fiscal Year 2020 on Feb. 6

On January 2, 2020 Cardinal Health (NYSE: CAH) reported to release second quarter financial results for its fiscal year 2020 on Feb. 6 prior to the opening of trading on the New York Stock Exchange (Press release, Cardinal Health, JAN 2, 2020, View Source [SID1234552673]). The company will webcast a discussion of these results beginning at 8:30 a.m. Eastern.

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To access the webcast and corresponding slide presentation, go to the Investor Relations page at ir.cardinalhealth.com. No access code is required.

Presentation slides and a webcast replay will be available on the Cardinal Health website at ir.cardinalhealth.com until Feb. 5, 2021.

Upcoming investor event
Mike Kaufmann, chief executive officer, will present at the 38th Annual J.P. Morgan Healthcare Conference on Monday, Jan. 13, 2020, at 10 a.m. Pacific in San Francisco. The presentation will be followed by a Q&A session. To access more details and to listen to a live webcast of this event, please visit the Investor Relations page at ir.cardinalhealth.com.

ORIC Pharmaceuticals to Present at the 38th Annual J.P. Morgan Healthcare Conference

On January 2, 2020 ORIC Pharmaceuticals, a privately held, clinical-stage oncology company focused on developing treatments that address mechanisms of therapeutic resistance, reported that Jacob Chacko, MD, the Company’s Chief Executive Officer, will present a company overview at the 38th Annual J.P. Morgan Healthcare Conference (Press release, ORIC Pharmaceuticals, JAN 2, 2020, View Source [SID1234552672]). Dr. Chacko’s presentation will take place on Tuesday, January 14, 2020, at 9:30 a.m. PST.

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Pulmatrix Announces Kinase Inhibitor Licensing Agreement with Lung Cancer Initiative at Johnson & Johnson

On January 2, 2020 Pulmatrix, Inc. (NASDAQ: PULM), a clinical stage biopharmaceutical company developing innovative inhaled therapies to address serious pulmonary diseases, reported that it has entered into a licensing and development agreement with the Lung Cancer Initiative at Johnson & Johnson (Press release, Pulmatrix, JAN 2, 2020, View Source;johnson-300980456.html [SID1234552671]). Through the agreement, the Lung Cancer Initiative gains an option to access a portfolio of narrow spectrum kinase inhibitors intended for development in lung cancer interception.

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"Pulmatrix’s iSPERSE platform has the ability to enhance the safety and efficacy profile of promising drug candidates," said Ted Raad, Chief Executive Officer of Pulmatrix. "We applied the iSPERSE technology to RV1162/PUR1800, the lead in-licensed inhibitor and helped unlock its clinical potential by improving the product’s profile from the original formulation. In 2020, we anticipate clinical data from the first of these inhibitors in a disease area with significant unmet medical need. We look forward to collaborating with the Lung Cancer Initiative at Johnson & Johnson as we advance this important program. Additionally, in 2020, we anticipate data from our phase 2 Pulmazole program and we plan to introduce new proprietary, wholly owned iSPERSE enabled 505(b)(2) assets to our pipeline."

Under the terms of the agreement, the Lung Cancer Initiative will pay a $7.2 million upfront payment and an additional $2 million milestone payment upon completion of the ongoing Phase 1b study of RV1162/PUR1800 in stable COPD patients, on-track for year-end 2020. If the Lung Cancer Initiative exercises the option on RV1162/PUR1800 and the portfolio of these kinase inhibitors, Pulmatrix is eligible for up to $91M in additional development and commercial milestones, as well as royalty payments.