Five Prime Therapeutics Announces Timing of Its Third Quarter 2020 Results Conference Call

On October 27, 2020 Five Prime Therapeutics, Inc. (NASDAQ: FPRX), a clinical-stage biotechnology company focused on developing immune modulators and precision therapies for solid tumor cancers, reported that it will report its third quarter 2020 operational and financial results on Tuesday, November 3, 2020 after the U.S. financial markets close (Press release, Five Prime Therapeutics, OCT 27, 2020, View Source [SID1234569148]). Five Prime will also host a conference call and live audio webcast on Tuesday, November 3, 2020 at 4:30 p.m. (ET) / 1:30 p.m. (PT) to provide a general business update and discuss the company’s financial results.

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The live audio webcast may be accessed through the "Events & Presentations" page in the "Investors" section of the company’s website at www.fiveprime.com. Alternatively, participants may dial (877) 878-2269 (domestic) or (253) 237-1188 (international) and refer to conference ID: 7757227

The archived conference call will be available on Five Prime’s website beginning approximately two hours after the event and will be archived and available for replay for at least 30 days after the event.

Scholar Rock Announces Proposed Public Offering of Common Stock

On October 27, 2020 Scholar Rock Holding Corporation (Nasdaq: SRRK), a clinical-stage biopharmaceutical company focused on the treatment of serious diseases in which protein growth factors play a fundamental role, reported that it intends to offer and sell in an underwritten public offering $150,000,000 of shares of its common stock (Press release, Scholar Rock, OCT 27, 2020, View Source [SID1234569147]). In addition, Scholar Rock intends to grant the underwriters a 30-day option to purchase up to an additional $22,500,000 of shares of common stock offered in the public offering. All of the shares are being offered by Scholar Rock. The offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

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Scholar Rock intends to use the net proceeds from the offering to advance SRK-015 in Spinal Muscular Atrophy, including costs associated with preparing for and executing clinical trials (including a Phase 3 clinical trial), SRK-181 in cancer immunotherapy, development of its preclinical and discovery programs, as well as for working capital and other general corporate purposes.

J.P. Morgan Securities LLC, Jefferies LLC and Credit Suisse Securities (USA) LLC are acting as joint book-running managers for the offering. BMO Capital Markets Corp. is acting as lead manager for the offering.

The securities described above are being offered by Scholar Rock pursuant to a shelf registration statement on Form S-3 (No. 333-231920) that was declared effective by the Securities and Exchange Commission (SEC) on June 10, 2019. A preliminary prospectus supplement and accompanying prospectus relating to the offering will be filed with the SEC and will be available on the SEC’s website located at www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus relating to this offering may be obtained, when available, by contacting: J.P. Morgan Securities LLC, Attention: Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, by telephone at 1-866-803-9204 or by email at [email protected]; Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by telephone at 877-547-6340 or by email at [email protected]; or Credit Suisse Securities (USA) LLC, Attention: Prospectus Department, 6933 Louis Stephens Drive, Morrisville, NC 27560, by telephone at (800) 221-1037 or by email at [email protected].

This press release does not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of that state or jurisdiction.

Humanigen to Present at Upcoming Investor Conferences

On October 27, 2020 Humanigen, Inc., (Nasdaq: HGEN) ("Humanigen"), a clinical stage biopharmaceutical company focused on preventing and treating an immune hyper-response called ‘cytokine storm’ with its lead drug candidate lenzilumab, reported that the Company’s management will present or participate in panel discussions at the following upcoming virtual investor conferences (Press release, Humanigen, OCT 27, 2020, View Source [SID1234569146]):

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ROTH Capital Healthcare Event – COVID-19 Therapeutics in Development (October 28, 2020)
Date: Wednesday, October 28
Panel series: Immune Modulators to Ameliorate COVID Sequelae 2
Panel time: 9:00 AM ET
Registration link: View Source

Bryan, Garnier & Co European Healthcare Conference (November 16-17, 2020)
Date: Monday, November 16
For more information: View Source

Stifel Virtual Healthcare Conference (November 16-18, 2020)
Date: Tuesday, November 17
Presentation time: 1:20 PM ET
Live webcast link: View Source

Jefferies London Healthcare Conference (November 17-19, 2020)
Date: Thursday, November 19
Presentation time: 6:45 PM GMT (2:45 PM ET)
Live webcast link: View Source

The conferences are being held in a virtual format. A live webcast of the presentation may be accessed on the Events section of the Humanigen website View Source Archived replay will be available on the Company website for 30 days following the event.

Personalis to Participate in Upcoming Investor Conferences

On October 4, 2020 Personalis, Inc. (Nasdaq: PSNL), a leader in advanced genomics for cancer, reported that company management will participate in the following upcoming investor conferences (Press release, Personalis, OCT 27, 2020, View Source [SID1234569145]).

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29th Annual Credit Suisse Virtual Healthcare Conference
Presenting on Tuesday, November 10, 2020 at 4:15 p.m. Eastern Time
Oppenheimer Fall MedTech Summit
Participating on Thursday, November 12, 2020

CivaTech Oncology and NYU Langone Health Launch NIH-sponsored Trial to Fight Lung Cancer

On October 27, 2020 Physicians from NYU Langone Health and its Perlmutter Cancer Center reported that successfully treated their first patient in an NIH/NCI- sponsored clinical trial using CivaSheet ,to improve lung cancer patients’ outcomes (Press release, CivaTech Oncology, OCT 27, 2020, View Source [SID1234569144]).

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The NYU Langone team, led by thoracic surgeon Michael Zervos, MD and radiation oncologist Benjamin Cooper, MD, affixed a custom sized CivaSheet to the area of the patient’s lung needing treatment, following a robotic tumor resection. The patient was thereby treated with a full course of radiation in a one-time therapy.

CivaSheet’s integrated shielding protects healthy surrounding organs, enabling a higher dose than can be administered using other treatment options. Implanting CivaSheet was completed in approximately 30 minutes. "CivaSheet provides patients optimal chance for a cure while also preserving lung tissue and maintaining maximum pulmonary function," said CivaTech Oncology’s Chief Medical Officer George Paschal MD.

Approximately 234,000 patients in the U.S. are diagnosed with lung cancer each year, and of those, 30- 55% with non-small cell lung cancer develop recurrence. CivaSheet, a new bio-absorbable, internal radiation treatment, is designed to help prevent a recurrence of lung cancer by delivering a highly targeted dose of radiation directly to the surgical margin where residual cancer cells may remain.

Designed and manufactured by CivaTech Oncology, CivaSheet is a flexible, implantable intra-operative radiation therapy device (brachytherapy), which emits unidirectional radiation using integrated gold shielding. The unidirectional property makes the device active on one side to provide a homogenous radiation dose. This feature is entirely unique to CivaSheet, allowing physicians to safely deliver aggressive radiation doses immediately adjacent to healthy, sensitive tissue. No complications or radiation related side effects have been reported in patients treated to date. Radiation is delivered over the course of several weeks as the isotope naturally decays, eliminating the need for repeat hospital visits, and no follow up procedure is necessary to remove the device.

CivaSheet has broad FDA clearance to include lung cancer and many other malignancies. This multi-center, NIH/NCI- sponsored research protocol will determine CivaSheet’s impact on local control rate. NYU Langone Health is participating in this clinical trial with several other nationally recognized cancer centers in the U.S.