On October 15, 2020 GT Biopharma, Inc. (OTCQB:GTBP) (GTBP.PA) an immuno-oncology company focused on innovative therapies based on the Company’s proprietary NK cell engager (TriKE) technology reported its abstract "GTB-3550 TriKE for the Treatment of High-Risk Myelodysplastic Syndromes (MDS) and Refractory/Relapsed Acute Myeloid Leukemia (AML) Safely Drives Natural Killer (NK) Cell Proliferation At Initial Dose Cohorts" has been selected by the Program Committee for presentation in an Oral Session at the 62nd American Society of Hematology (ASH) (Free ASH Whitepaper) Annual Meeting and Exposition as detailed below (Press release, GT Biopharma, OCT 15, 2020, View Source [SID1234568505]):

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Session Name: 704. Immunotherapies: Beyond T to NK
Session Date: Saturday, December 5, 2020
Session Time: 7:30 AM – 9:00 AM
Presentation Time: 8:00 AM

The ASH (Free ASH Whitepaper) Annual Meeting & Exposition is the premier event in malignant and non-malignant hematology. ASH (Free ASH Whitepaper) has more than 18,000 members from nearly 100 countries. ASH (Free ASH Whitepaper) is the world’s largest professional society serving both clinicians and scientists around the world who are working to conquer blood diseases.

In addition to the presentation, your abstract will also be published online in November supplemental issue of the journal Blood. First publication will be in the online ASH (Free ASH Whitepaper) meeting program on November 5, 2020.

Mr. Anthony Cataldo, the Chairman and Chief Executive Officer of GT Biopharma commented "we are pleased to have the opportunity to present our interim results for GTB-3550 TriKE for the treatment of High-Risk Myelodysplastic Syndromes (MDS) and Refractory/Relapsed Acute Myeloid Leukemia (AML) patients."

On October 15, 2020 Advaxis, Inc. (Nasdaq: ADXS), a clinical-stage biotechnology company focused on the development and commercialization of immunotherapy products, reported it will present an ePoster at the 35th Annual Meeting of the Society for Immunology of Cancer (SITC 2020) to be held virtually November 9-14, 2020 (Press release, Advaxis, OCT 15, 2020, View Source [SID1234568504]).

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Title: "Phase 1/2 Study of an Off-the-Shelf, Multi-Neoantigen Vector (ADXS-503) Alone and in Combination with Pembrolizumab in Subjects with Metastatic Non-Small Cell Lung Cancer (NSCLC)"
Presenter: Dr. Jonathan W. Goldman. University of California Los Angeles, Santa Monica, CA
Abstract ID: 360
Date and Time: Thursday, November 12th from 4:50 pm until 5:20 pm ET and Saturday, November 14th from 1:00 pm until 1:30 pm ET.

The poster will be available on Advaxis’ website at View Source

On October 15, 2020 F. Hoffmann-La Roche Ltd. (hereafter "Roche") [Head Office: Basel, Switzerland. CEO: Severin Schwan] reported its third quarter sales 2020 (January 1 – September 30, 2020) (Press release, Chugai, OCT 15, 2020, View Source [SID1234568500]).

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Roche owns 59.89% of Chugai’s outstanding shares (61.17% of the total number of shares issued excluding treasury stock) as of the end of September 2020.

Its press release and presentation materials can be found on its website (View Source).
Chugai’s performance for the period of January 1 to September 30, 2020 is included in the announced Roche Group’s results.

On October 15, 2020 Cancer Research Center of Toulouse reported that Coordinated by the European Biomedical Imaging Research Institute (EIBIR, Austria), the H2020 MEDIRAD project (View Source) is based on a consortium of 33 partners representing 14 European countries (Press release, Cancer Research Center of Toulouse, OCT 15, 2020, View Source [SID1234568499]). This project aims to explore the effects of low-dose exposure in medicine.

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More generally, the MEDIRAD project will improve the scientific basis and practice of radiation protection in medicine, with the aim of preventing the risks associated with repeated exposure to low doses of radiation (e.g.: cardiovascular risks following radiotherapy treatment of breast cancer/ long-term risks of tomography treatments in children and adolescents, etc.).

Among the applications concerned is the use of iodine-131 for the treatment of thyroid cancers (WP3 – coordinator: Glenn Flux). Team 15 of the CRCT (responsible: Pr M. Bardiès) is involved in this project (dosimetry axis), and the IUCT-Oncopole is the only French institution to participate in clinical research (coordinator: Pr F. Courbon).

As a reminder, iodine-131 has been used to treat thyroid cancers for over 80 years, with excellent results. However, this practice raises the question of the potential risks to healthy organs away from the treated area. A network of expert centres capable of producing standardised scintigraphic imaging data has been set up within MEDIRAD to enable the precise determination of the doses absorbed by healthy organs during these treatments, first step in assessing the risks associated with treatment.

In this perspective, four European centres (including the IUCT-Oncopole) initially compared their scintigraphic image acquisition systems (five in total), according to three main criteria: detector sensitivity, contrast recovery coefficients and dead time. The objective was to provide elements of camera parameterization methodology for each of the models analyzed and to ensure the standardization of acquisitions and associated processing. These results, preliminary but essential for the continuation of the project, were published this month in The European Journal of Nuclear Medicine and Molecular Imaging.

On October 15, 2020 BioInvent International AB ("BioInvent") (OMXS: BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, reported that they will be presenting a poster on BI-1808, an antibody to tumor necrosis factor receptor 2 (TNFR2), at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) 35th Anniversary Annual Meeting (Press release, BioInvent, OCT 15, 2020, View Source [SID1234568495]). The congress will be held virtually from November 9 to 14, 2020 .

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Title of abstract: Pre-clinical development of TNFR2 ligand-blocking BI-1808 for cancer immunotherapy
Authors: Linda Mårtensson, Mathilda Kovacek, Petra Holmkvist, Monika Semmrich, Carolin Svensson, Therese Blidberg, Carl Roos, Andres McAllister, Mimoza Demiri, Marie Borggren, Ingrid Karlsson, Björn Frendéus, Ingrid Teige
Abstract number: 725

The poster will be available in the Virtual Poster Hall November 11-14, 2020, 9:00 a.m. – 5:00 p.m. EST (3:00 – 11:00 p.m. CET). The presenting authors will answer questions on Wednesday, November 11 from 5:15 to 5:45 p.m. EST (11:15 – 11: 45 p.m. CET) and Friday, November 13 from 4:40 to 5:10 p.m. EST (10:40 – 11: 10 p.m. CET).