On June 16, 2021 Nkarta, Inc. (Nasdaq: NKTX), a biopharmaceutical company developing engineered natural killer (NK) cell therapies to treat cancer, reported its participation at this upcoming investor conference(Press release, Nkarta, JUN 16, 2021, View Source [SID1234584043]):

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Raymond James Human Health Innovation Conference
June 21, 2021
3:20 p.m. ET – fireside chat presentation

The live webcast of the presentation will be available on the Investors section of Nkarta’s website, www.nkartatx.com. A replay of the webcast will be archived on the website for approximately four weeks.

On June 16, 2021 Jounce Therapeutics, Inc. (NASDAQ: JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, reported that it will host a virtual R&D Day at 10:00 a.m. – 12:00 p.m. ET on Wednesday, June 23, 2021(Press release, Jounce Therapeutics, JUN 16, 2021, View Source [SID1234584042]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The event will feature presentations and a Q&A session from Jounce management and scientific team members, in addition to key opinion leader and a Jounce scientific founder, Robert Schreiber, PhD, The Washington University School of Medicine.

A webcast of the R&D Day will be available by visiting "Events and Presentations" in the Investors and Media section of Jounce’s website at www.jouncetx.com. A replay of the webcast will be available for 30 days following the presentation.

On June 16, 2021 Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., "Astellas") reported that Astellas and Cheplapharm Arzneimittel GmbH ("Cheplapharm") have enterd into an Asset Purchase Agreement, under which Astellas will transfer the Products Rights for five legacy products (the "Products") in certain countries of Europe, Russia, Commonwealth of Independent States (CIS)1 and Asia(Press release, Astellas, JUN 16, 2021, View Source [SID1234584040]).

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Once the transaction closes, Cheplapharm will take over the Products Rights from Astellas and sell them in certain countries of Europe, Russia, CIS and Asia. Astellas will work closely with Cheplapharm to enable a smooth transition.

(1) Purpose of Asset Purchase Agreement
The agreement is a part of Astellas’ ongoing efforts to improve the quality and efficiency of operations so as to accommodate the rapidly changing business environment and achieve sustainable growth. Astellas will continue to strengthen our business presence in Europe, Russia, CIS, and Asia through optimization of resource allocation.

(2) Financial Terms of Asset Purchase Agreement
€95 million

(3) Schedule of Asset Purchase Agreement
June 15, 2021: Signing of the Asset Purchase Agreement
September 2021 or later: Closing of the transaction(tentative)

After closing of the transaction, the Products Rights for the Products will be transferred in each country.

(4) List of the Products

Products Name Indication
FLEMOXIN Acute respiratory infections, Helicobacter pylori associated diseases, such as gastritis and gastric ulcer, urogenital infections and others
DE-NOL Gastro protector with antibacterial effect on H. pylori
SUPRAX Chronic and recurrent respiratory infections with the highest activity towards H. influenzae. Infections caused by susceptible bacteria, such as urinary tract infections and others, e.g. skin, secondary infection in trauma, burn or surgical wound, cholangitis
UNIDOX Infections, such as mild community acquired pneumonia, acute exacerbations of chronic bronchitis, lymphogranuloma venereum, acne vulgaris, chlamydia trachomatis infections, prostatitis, cervicitis and pelvic inflammatory diseases
ORBENINE Infections caused by gram-positive organisms (except MRSA and MRSE), including infections caused by beta-lactamase producing staphylococci

(5) Sales of the Products
€81.5 million(fiscal year ended March 31, 2021)

Astellas has already reflected the impact from this transaction in its financial forecast of the current fiscal year ending March 31, 2022.

On June 15, 2021 Acorda Therapeutics, Inc. (Nasdaq: ACOR) reported that on June 15, 2021, it repaid in full its 1.75% Convertible Senior Notes due 2021(Press release, Acorda Therapeutics, JUN 16, 2021, View Source [SID1234584039]). Prior to their maturity and repayment, there were $69.0 million aggregate principal amount of 2021 notes outstanding. The 2021 notes were repaid using cash on hand.

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"The repayment of the 2021 notes removes an overhang on the company and is another important milestone in our strategy, following the sale of our manufacturing operations earlier this year. We are focused on accelerating the growth of INBRIJA, continuing to maintain the strength of AMPYRA, and optimizing the company’s financial structure," said Ron Cohen, M.D., Acorda’s President and Chief Executive Officer. "We have maintained cost discipline since our restructuring announcement in February and are continuing to drive toward cash flow breakeven.

On June 16, 2021 Innate Pharma SA (Euronext Paris: IPH – ISIN: FR0010331421; Nasdaq: IPHA) ("Innate" or the "Company") reported that it will host a virtual investor event on Wednesday, June 23, 2021, at 2 p.m. CEST / 8 a.m. EDT(Press release, Innate Pharma, JUN 16, 2021, View Source [SID1234584032]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The event will feature presentations and an interactive Q&A session from the Company’s executive leadership team as well as Martine Bagot, M.D., Ph.D., Professor and Head of the Dermatology Department at the Saint-Louis Hospital, University of Paris, France.

Pr. Bagot will present preliminary mycosis fungoides data from the Company’s Phase 2 TELLOMAK trial evaluating its lead product, lacutamab, an anti-KIR3DL2 cytotoxicity-inducing antibody in development for T-cell lymphomas. This preliminary data will be presented as an oral presentation at the 16th International Conference on Malignant Lymphoma (16-ICML) on June 22.

Additionally, the Company’s Chief Scientific Officer, Pr. Eric Vivier, DVM, Ph.D., will present preclinical data from ANKETTM (Antibody-based NK cell Engager Therapeutics), Innate’s proprietary platform for developing next-generation, multi-functional NK cell engagers. These new data were presented at the Federation of Clinical Immunology Societies (FOCIS) Virtual Annual Meeting on June 10.