Ana Patricia Gámez Joins Cancer Research Institute in the Movement for Racial Health Equity, Named Moderator of First Spanish-Language Virtual Cancer Immunotherapy Summit

On August 23, 2021 The Cancer Research Institute (CRI), a nonprofit organization spearheading transformative research to harness the immune system’s power to control and potentially cure all cancers, reported that it will offer its first-ever Virtual Cancer Immunotherapy Summit in Spanish on September 16, 2021, 2-5 p.m. ET (Press release, Cancer Research Institute, AUG 23, 2021, View Source [SID1234586835]). This free interactive online event, moderated by TV personality, podcast host, and former national Univision & Unimas TV host, Ana Patricia Gámez, will connect cancer patients and caregivers with revolutionary research updates from leading immunotherapy experts driving scientific discovery and advancement.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

According to the Center for Disease Control (CDC), cancer is the leading cause of death among Hispanic people, with current cancer research and statistics indicating lung, breast, and colorectal cancer having the greatest impact in this community. Studies show that lung cancer is the leading cause of cancer death among U.S. Hispanic men and the second leading cause of cancer death among U.S. Hispanic women. Breast cancer is the leading cause of death in Hispanic females and colorectal cancer is the third leading cause of cancer death among both Hispanic men and women.

In fact, research indicates that one in three U.S. Hispanic people (both women and men alike) will be diagnosed with cancer in their lifetime. This urgent public health crisis has propelled the Cancer Research Institute to lead the charge in bringing the promise of immunotherapy to this underserved community with in-language information, research updates, and clinical trial access. Cancer immunotherapy is a form of cancer treatment that uses the body’s own immune system to control and eliminate cancer.

"I’ve dedicated my career to the research and development of immunotherapy as an effective cancer treatment. Sharing information in Spanish about this revolutionary treatment option with U.S. Hispanic patients is urgently needed and allows me the opportunity to positively impact the lives of this community as well as support the Cancer Research Institute’s efforts for racial health equity," said Antoni Ribas, M.D., Ph.D., member of the CRI Scientific Advisory Council, director of the Tumor Immunology Program at the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, and the chair of the Melanoma Committee at SWOG Cancer Research Network.

"Working with leaders in the immunotherapy field and leveraging the reach of our partners such as Univision and Ana Patricia Gámez, we hope to engage with U.S. Hispanic cancer patients, survivors, caregivers, and support systems to positively impact the health, wellbeing, and overall cancer outcomes for the U.S. Hispanic community," said Jill O’Donnell-Tormey, Ph.D., CEO and director of scientific affairs at CRI. "Hispanic people are underrepresented when it comes to accessing quality cancer care. The number of patients getting the best treatment isn’t proportional to the number of people who need that treatment. The lack of diversity in cancer clinical trials, too, is a major issue that slows discovery, so CRI is committed to helping solve this problem by connecting U.S. Hispanic patients with leading physician-scientists who want just one thing—to cure cancer."

"It’s my honor to serve as the moderator for the first-ever CRI Virtual Cancer Immunotherapy Summit in Spanish," said Ana Patricia Gámez. "My connection to cancer is personal and real—I lost my father much too soon and that changed my life forever. It is my privilege to help Hispanic cancer patients and caregivers in their healthcare journey. This event gives me the chance to do my part to provide these mothers, fathers, and family members with access to the latest information on cancer treatments and clinical trials."

From the comfort and safety of home, attendees of the first-ever free CRI Virtual Cancer Immunotherapy Summit in Spanish can expect to:

Learn about immunotherapy and how it helps patients, caregivers, and their families
Hear from leading physician-scientists with expertise in cancer immunotherapy as well as patients treated with immunotherapy
Gain valuable insight into how clinical trials work to understand whether they are a good option for cancer patients or a loved one and how to find one
Discover issues specific to the Hispanic and Latino communities in the United States regarding cancer care and how doctors, organizations, advocates, and individuals are addressing these challenges
Support for the Spanish-language 2021 CRI Virtual Cancer Immunotherapy Summit is generously provided by the following sponsors:

Univision, official media sponsor
Bristol Myers Squibb, Merck (also know as MSD outside the U.S.), Lily Oncology and Alkermes Inspiration Grant
This summit comes on the heels of the launch of the first-ever Spanish-language cancer immunotherapy information hub to connect Hispanic patients and caregivers with the latest research and treatment options. The Cancer Research Institute is committed to closing the information and research gap to better serve the Hispanic community in the United States. Visit cancerresearch.org/es to see the robust and helpful offering of information now available in Spanish. Visit cancerresearch.org/es/conferencia to register for the Spanish-language 2021 CRI Virtual Cancer Immunotherapy Summit.

Lightpoint Medical and Telix Pharmaceuticals Announce Strategic Collaboration Agreement

On August 23, 2021 Lightpoint Medical, a leading medical device company developing and marketing miniaturized imaging and sensing tools for minimally-invasive and robot-assisted surgery, repored that it has signed a strategic collaboration agreement with Telix Pharmaceuticals Limited (Press release, lightpoint medical, AUG 23, 2021, View Source [SID1234586832]). Under the agreement, the two companies will explore how Lightpoint and Telix technologies may be used together for real-time intra-operative cancer detection.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

SENSEI, Lightpoint Medical’s miniature surgical gamma probe, to be used with Telix’s imaging agent TLX599-CDx in prostate cancer surgery
SENSEI, Lightpoint Medical’s miniature surgical gamma probe, to be used with Telix’s imaging agent TLX599-CDx in prostate cancer surgery
Lightpoint has developed SENSEI, a miniaturized surgical gamma probe for minimally-invasive and robot-assisted cancer surgery, approved for sale in the US, EU, UK and Australia. SENSEI can be used with molecularly-targeted imaging agents, promising direct detection of cancer during surgery to help guide surgeons in the removal of cancer and the sparing of healthy, functional tissue.

Lightpoint and Telix will first evaluate the use of SENSEI with Telix’s investigational prostate cancer single photon emission computed tomography (SPECT) imaging agent TLX599-CDx (99mTc-HYNIC-iPSMA) for the intra-operative detection of cancerous pelvic lymph nodes. The objective of the collaboration is regulatory approval and commercialization of SENSEI and TLX599-CDx for prostate cancer surgery.

Lightpoint CEO, Graeme Smith said "This strategic partnership agreement with Telix marks an important milestone for Lightpoint Medical. The combination of our miniaturized surgical gamma probe, SENSEI, alongside Telix’s ground-breaking imaging agents is intended to create an extremely precise technique to help surgeons detect cancer that might not otherwise be found during surgery, or conversely, confirm the absence of disease to help surgeons retain healthy, functional tissue. The collaboration between our two companies has the potential to transform surgical outcomes for patients across a range of major cancer types, starting with prostate cancer."

Telix CEO, Dr. Christian Behrenbruch added "Bringing molecular imaging into the operating theatre is a key part of our portfolio strategy for urologic oncology, and the combination of Telix and Lightpoint technologies has the potential to transform treatment options for patients with cancer. This collaboration helps to reinforce Telix’s position as a leader in developing advanced surgical technologies using highly targeted imaging techniques."

About TLX599-CDx

TLX599-CDx is an investigational product being developed by Telix to facilitate patient access to advanced prostate cancer imaging in countries where SPECT imaging is predominant in healthcare facilities. Whereas Telix’s lead investigational product, Illuccix for prostate cancer imaging, utilises positron emission tomography (PET), TLX599-CDx employs SPECT, a diagnostic imaging technology that is more widely available in healthcare facilities throughout the world. In April 2021 Telix announced the launch of the NOBLE Registry[1], a global consortium of investigator-led studies exploring the clinical utility of TLX599-CDx, with the objective to generate data and facilitate the design of future formal registration clinical trials.

PharmAbcine to Participate in H.C. Wainright 23rd Annual Global Investment Conference

On August 23, 2021 PharmAbcine Inc. (KOSDAQ: 208340ks), a clinical-stage biotech company focusing on the development of next generation antibody therapeutics, reported that the Company will participate in H.C. Wainright 23rd Annual Global Investment Conference taking place virtually from September 13-15, 2021 (Press release, PharmAbcine, AUG 23, 2021, https://www.prnewswire.com/news-releases/pharmabcine-to-participate-in-hc-wainright-23rd-annual-global-investment-conference-301359591.html [SID1234586831]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

During the conference, Dr. Jin-San Yoo, CEO of PharmAbcine, will update PharmAbcine’s R&D progress via a presentation video, highlighting the Company’s core technology and pipelines such as olinvacimab, PMC-403, and PMC-309.

Olinvacimab, an anti-VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) fully human antibody, is the Company’s leading pipeline and is undergoing multiple global clinical trials. Currently, a Phase II olinvacimab mono study for bevacizumab-nonresponding rGBM (recurrent glioblastoma multiforme) patients is taking place at multiple sites in both US and Australia. Also, there are two Phase Ib olinvacimab and pembrolizumab combo trials in mTNBC and rGBM still ongoing in Australia.

PMC-403 is a novel TIE2-activating fully human antibody designed to stabilize and repair damaged blood vessels in a variety of diseases. PMC-403 is currently in development for treating AMD (Age-related Macular Degeneration), DME (Diabetic Macular Edema), and DR (Diabetic Retinopathy) which are common abnormal vascular-related eye diseases. The Company expects PMC-403 to enter global clinical trials for both ophthalmology and oncology in 2022.

PMC-309 is a novel anti-VISTA (V-domain Ig Suppressor of T cell Activation) antagonizing antibody in development for the treatment of various tumor types. VISTA plays a pivotal role in maintaining the immunosuppressive environment around the tumor cells and is expressed primarily on MDSC (Myeloid-Derived Suppressor Cells) and Tregs (regulatory T cells). Blocking VISTA pathways activates T cells’ immune responses and leads to better anti-tumor effects. PMC-309 is expected to enter a global clinical trial in 2022.

The Company will also join one-on-one meetings with institutional investors and private equity firms to seek investment opportunities.

The presentation video can be accessed at 7:00 AM (Eastern Standard Time) on Monday, September 13, 2021 and will be available for 90 days. For the webcasting link, request here.

About H.C. Wainwright & Co.

H.C. Wainwright is a full–service investment bank dedicated to providing corporate finance, strategic advisory and related services to public and private companies across multiple sectors and regions. H.C. Wainwright & Co. also provides research and sales and trading services to institutional investors. According to Sagient Research Systems, H.C. Wainwright’s team is ranked as the #1 Placement Agent in terms of aggregate CMPO (confidentially marketed public offering), RD (registered direct offering) and PIPE (private investment in public equity) executed cumulatively since 1998.

Affimed to Report Second Quarter 2021 Financial Results & Corporate Update on September 8, 2021

On August 23, 2021 Affimed N.V. (Nasdaq: AFMD), a clinical stage immuno-oncology company committed to giving patients back their innate ability to fight cancer, reported that it will release second quarter 2021 results on Wednesday, September 8, 2021, and host a conference call at 8:30 a.m. EDT to discuss financial results and recent corporate developments (Press release, Affimed, AUG 23, 2021, View Source [SID1234586830]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The conference call will be available via phone and webcast. To access the call, please dial +1 (409) 220-9054 for U.S. callers, or +44 (0) 8000 323836 for international callers, and reference passcode 6156773 approximately 15 minutes prior to the call. To access the live audio webcast of the conference call please visit the "Investors" section of company’s website at View Source A replay of the call will be archived on the Affimed website for 30 days after the call.

Allarity Therapeutics Publishes Interim Report for the Period January – June 2021

On August 23, 2021 Allarity Therapeutics A/S ("Allarity" or the "Company") reported the publication of its Interim Report for the period January – June 2021 (Press release, Allarity Therapeutics, AUG 23, 2021, View Source [SID1234586829]). The report is available as an attached document and on the Company’s website.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Steve Carchedi, CEO of Allarity Therapeutics, commented on the Company’s accomplishments during the period, stating , "In July, we successfully out-monetized our last remaining secondary pipeline program, irofulven. Shortly after our divestment of Irofulven, we, following positive results of our pre-clinical testing of stenoparib against numerous variants of the original Sars-CoV 2 strain, announced that we are initiating pre-clinical testing of stenoparib for activity against the delta variant (B.1.617.2). Also, in July, we announced that the U.S. Food and Drug Administration had provided a positive administrative acceptance and review notification for our pre-market approval application for our Dovitinib-DRP. Earlier, in June, we announced that our Rights Offering had been oversubscribed, netting approximately U.S. $12 million of crucial working capital. Lastly, in May, we announced that Allarity has entered into an agreement with 3i Fund for a U.S. $20 million investment to support Allarity’s recapitalization and reorganization into a U.S listed company."

Summary of the Interim Report for Q2 2021

Consolidated group revenue amounted to 0 MDKK (0 MDKK).
Consolidated group loss before depreciation amounted to -30.7 MDKK (-5.2 MDKK).
Consolidated group loss before net financials amounted to -89.8 MDKK (-5.5 MDKK).
Consolidated net result amounted to -92.1 MDKK (-3.5 MDKK).
Consolidated earnings per share (EPS) amounted to -0.37 DKK (-0.03 DKK).

2020 numbers in brackets.

Highlights during Q2 2021

April

On April 2, the Company submitted a Pre-Market Approval (PMA) application to the U.S. FDA for the DRP companion diagnostic for dovitinib.
On April 15, the Company published the minutes of the Annual General Meeting 2021.
On April 29, the Company announced that a Dovitinib-DRP e-Poster would be presented at the EACR 2021 Virtual Congress to be held from 9-12 June 2021.

May

On May 19, the Company announced that it would conduct a Rights Issue of new shares, and it had published a prospectus regarding the Rights Issue.
On May 21, the Company announced that it had secured an investment from 3i Fund for recapitalization, transition to listing on U.S. Nasdaq, and advancing the Company’s pipeline of priority oncology therapeutics.
On May 28, the Company published the Interim Report for the period January – March 2021

June

On June 9, the Company published an E-Poster detailing the molecular pathways covered by the Dovitinib-DRP companion diagnostic
On June 10, the Company announced that the rights issue had been oversubscribed
On June 14, it was announced that Allarity Therapeutics and Oncoheroes Biosciences had to partnered on pediatric cancer development of dovitinib and stenoparib
On June 24, the last day of trading with Allarity Therapeutics A/S BTU was announced

Highlights after the period

July

On July 5, the Company received an acceptance and review notification from U.S. FDA for Pre-Market Approval application for Dovitinib-DRP
On July 26, it was announced that the Company and Lantern Pharma entered into an agreement for Future Clinical Development of Irofulven
August

On August 5, the Company announced that its oral PARP inhibitor, stenoparib, had demonstrated pre-clinical antiviral activity against new variants of Coronavirus
On August 16, a notice to convene an Extraordinary General Meeting on August 31, 2021, was announced