Ultragenyx to Present at Jefferies Gene Therapy/Editing Summit

On October 25, 2021 Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), a biopharmaceutical company focused on the development and commercialization of novel therapies for serious rare and ultra-rare genetic diseases, reported that Emil D. Kakkis, M.D., Ph.D., the company’s Chief Executive Officer and President, will present at the Jefferies Gene Therapy/Editing Summit on October 28, 2021 at 3:30 PM ET (Press release, Ultragenyx Pharmaceutical, OCT 25, 2021, View Source [SID1234591897]).

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The live and archived webcast of the presentation will be accessible from the company’s website at View Source The replay of the webcast will be available for 90 days.

Iovance Biotherapeutics to Host Third Quarter Financial Results Conference Call and Webcast on Thursday, November 4, 2021

On October 25, 2021 Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a late-stage biotechnology company developing novel T cell-based cancer immunotherapies, reported that it will report its third quarter financial results on Thursday, November 4, 2021 (Press release, Iovance Biotherapeutics, OCT 25, 2021, View Source [SID1234591895]). Management will host a conference call and live audio webcast to discuss these results and provide a corporate update at 4:30 p.m. ET.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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To participate in the conference call, please dial 1-844-646-4465 (domestic) or 1-615-247-0257 (international) and reference the access code 7286232. The live webcast can be accessed in the Investors section of the Company’s website at www.iovance.com. The archived webcast will also be available for one year in the Investors section at www.iovance.com.

Invitation to presentation of Q3 2021 results

On October 25, 2021 ArcticZymes Technologies reported for the third quarter 2021 on Thursday, 28. October 2021 at 08.30 a.m (Press release, Biotec Pharmacon, OCT 25, 2021, View Source [SID1234591894])

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The company will host an online presentation for investors, analysts, and media at 08:30 a.m on Thursday, 28 October 2021, which will be followed by a Q&A session.

CEO, Jethro Holter and CFO, Børge Sørvoll will hold the presentation.

Participants who want to participate in the live webcast are asked to send an email to [email protected] for a separate invitation, which will be distributed 1 day prior to the meeting. Participants who want to participate by telephone should dial in on +47 21 40 24 87 with conference id: 220 624 781#. It will be possible to post questions through the webcast and over the phone after the presentation is finished.

The report for the third quarter 2021 will be available on www.newsweb.no and on the company’s homepage www.arcticzymes.com from 07.00 a.m. on Thursday, 28. October 2021.

Cardinal Health expands solutions to mitigate missed cancer screenings

On October 25, 2021 Cardinal Health (NYSE: CAH) reported its cancer screening offerings from FUJIFILM Healthcare Americas Corporation and Polymedco that can be done either outside of a doctor’s office or with less invasive procedures can help combat the increase in cancer-related deaths due to late-stage diagnoses1 from pandemic-related delays (Press release, Cardinal Health, OCT 25, 2021, View Source [SID1234591892]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Cardinal Health, Inc. is a global, integrated healthcare services and products company, providing customized solutions for hospitals, healthcare systems, pharmacies, ambulatory surgery centers, clinical laboratories and physician offices worldwide. (PRNewsfoto/Cardinal Health)

"The pandemic has changed the landscape of traditional diagnostic methods and is driving the healthcare industry to evaluate screenings differently," added Chris Kerski, general manager and senior vice president of Cardinal Health Laboratory Products. "We’re adding new testing solutions to our portfolio to reduce barriers to screening and support patient-led cancer screenings."

Colon Cancer

According to a report in JAMA Oncology2, nearly 10 million cancer screenings for breast, colon and prostate cancer were missed in the U.S. since the pandemic began. Researchers recently reported a more than 40% decline in colon cancer diagnoses alone during the pandemic, a statistic that points to missed screenings, not fewer cases3.

"A missed screening increases the likelihood of a late-stage cancer diagnosis, which is associated with poor prognosis," says Nicholas Sullivan, Ph.D., a senior product manager at Cardinal Health Laboratory Products with a background in cancer biology and clinical laboratory medicine. "This high number of missed screenings during the pandemic has the potential to impact cancer patient outcomes for years."

During the pandemic, some health systems and health plans began proactively mailing screening collection kits to patients, rather than waiting for patients to come in for a routine visit or colonoscopy4. Cardinal Health works with Polymedco to offer OC-AutoFIT, which detects small amounts of blood in stool – an early indication of colon cancer5. Different than a colonoscopy, patients don’t have to prep in advance of the test and can do the stool specimen collection at home.

Liver Cancer

Liver cancer is one of the top-three leading causes of cancer-related deaths worldwide6 accounting for more than 700,000 deaths each year7.

In November 2020, Cardinal Health became the first distributor of Fujifilm’s innovative solution, the µTASWako i30 Immunoanalyzer System testing for liver biomarkers AFP-L3 and DCP using a simple blood draw. These biomarkers aid in the risk assessment of patients with chronic liver disease for the development of hepatocellular carcinoma (HCC), the most common type of liver cancer8.

HCC surveillance is critical for those at-risk for liver cancer given its lethality. A recent study9 reported that liver cancer surveillance dramatically declined during the pandemic and that "a delay of just a few months in HCC surveillance may be catastrophic for patients, given that the doubling time for HCC tumor volume is 85.7 days." Only 20% of those patients at risk of developing liver cancer receive surveillance10.

Cardinal Health now offers Fujifilm’s automated solution to enhance clinical lab customers’ liver surveillance cancer programs.

Cancer screening access

As a trusted advisor to the clinical laboratory market, Cardinal Health advocates for the important role diagnostic testing plays in improving healthcare.

"These critical expansions of our cancer screening offerings, coupled with our robust anatomic pathology and laboratory kitting services, underscore our commitment to making healthcare more accessible for patients. We must stay vigilant in preventative care through the utilization of easy-to-access screening tools and draw more awareness to the secondary impacts of the pandemic," says Kerski.

Panbela Schedules Conference Call on Nov 10 to Report Q3 2021 Financial Results

On October 25, 2021 Panbela Therapeutics, Inc. (Nasdaq: PBLA), a clinical stage biopharmaceutical company developing disruptive therapeutics for the treatment of patients with cancer, reported that it will host a conference call on November 10, 2021, at 4:30 PM Eastern Time to discuss results for its third quarter ended September 30, 2021 (Press release, Panbela Therapeutics, OCT 25, 2021, View Source [SID1234591891]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Conference Call Information

To participate in this event, dial approximately 5 to 10 minutes before the beginning of the call.

Webcast replay: View Source

About SBP-101
SBP-101 is a proprietary polyamine analogue designed to induce polyamine metabolic inhibition (PMI) by exploiting an observed high affinity of the compound for pancreatic ductal adenocarcinoma and other tumors. The molecule has shown signals of tumor growth inhibition in clinical studies of US and Australian metastatic pancreatic cancer patients, suggesting potential complementary activity with an existing FDA-approved standard chemotherapy regimen. In data evaluated from clinical studies to date, SBP-101 has not shown exacerbation of bone marrow suppression and peripheral neuropathy, which can be chemotherapy-related adverse events. Recently observed serious visual adverse events have been evaluated and patients with a history of retinopathy or at risk of retinal detachment will be excluded from future SBP-101 studies. The safety data and PMI profile observed in the current Panbela sponsored clinical trial provides support for continued evaluation of SBP-101 in a randomized clinical trial. For more information, please visit View Source .