Aucentra Receives Seed-Start Grant

On December 14, 2021 Aucentra reported that it is excited to be awarded a seed-start grant of $700k by the South Australian government’s research and innovation fund (Press release, Aucentra, DEC 14, 2021, View Source [SID1234606756]). This funding will be used to test Aucentra’s leading drug candidate Auceliciclib.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Auceliciclib, if successful in its clinical trials, will be a game-changing treatment of glioblastoma multiforme, which is the most aggressive type of brain cancer and the most difficult to treat.

The Minister for Innovation and Skills David Pisoni recognised Aucentra’s ground-breaking achievements; "I am incredibly proud of Professor Wang and her team at the University of South Australia for the amazing work they have accomplished".

Auceliciclib is a CDK4 and 6 inhibitor with a high specificity which allows for prevention of cancer cell growth and proliferation with fewer side effects. Read the full article here: View Source

Grant funding awarded

On December 14, 2021 Aucentra reported that it is excited to be awarded a seed-start grant of $700k by the South Australian government’s research and innovation fund (Press release, Aucentra, DEC 14, 2021, View Source [SID1234598161]). This funding will be used to test Aucentra’s leading drug candidate Auceliciclib.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Auceliciclib, if successful in its clinical trials, will be a game-changing treatment of glioblastoma multiforme, which is the most aggressive type of brain cancer and the most difficult to treat.

The Minister for Innovation and Skills David Pisoni recognised Aucentra’s ground-breaking achievements; "I am incredibly proud of Professor Wang and her team at the University of South Australia for the amazing work they have accomplished".

Auceliciclib is a CDK4 and 6 inhibitor with a high specificity which allows for prevention of cancer cell growth and proliferation with fewer side effects. Read the full article here: View Source

Carterra and PerkinElmer Sign Distribution Agreement For Asia-Pacific and Oceania Region for Carterra’s High Throughput Antibody Screening and Characterization Solutions

On December 14, 2021 Carterra, Inc. the world leader in label-free high throughput antibody screening and characterization, reported that it has signed an exclusive Asia-Pacific and Oceania region distribution agreement with PerkinElmer, Inc. a global leader committed to innovating for a healthier world (Press release, PerkinElmer, DEC 14, 2021, View Source [SID1234597443]). With the agreement, PerkinElmer will market, sell, and service Carterra’s flagship LSA high-throughput surface plasmon resonance (SPR) platform and software used for accelerating the discovery of therapeutic antibodies.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

This move will assist Carterra in meeting growing customer demand by leveraging PerkinElmer’s long-standing channel infrastructure in the region. It will also add additional tools to PerkinElmer’s growing portfolio of science and biologics discovery offerings, which includes its world leading BioLegend antibody and reagent technologies.

This new agreement builds on the equity investment PerkinElmer made in Carterra last December, which has resulted in several collaborations between the companies involving assay development and software integration projects over the past year.

Commenting on this latest distribution arrangement, Alan Fletcher, Senior Vice President, Life Science, PerkinElmer, said, "We are delighted to add the distribution of Carterra’s highly innovative LSA technology to help our Asia-Pacific and Oceania customers further streamline and advance their biologic and biotherapeutic discovery and development work."

"Carterra recognized early on that Asia-Pacific and Oceania would be important markets for our game changing biologics discovery products and we are at the point where we need additional reach and channel power to help us take our customer delivery there to the next level, " stated Tim Germann, Chief Commercial Officer at Carterra. "We are excited to collaborate with PerkinElmer to add that extra horsepower in sales, marketing and service as well as benefit from their deep life science expertise across drug development workflows."

PCI Biotech to present at DNB Nordic Healthcare Conference 2021

On December 14, 2021 PCI Biotech (OSE: PCIB), a clinical-stage biopharma company developing innovative therapeutics that address significant unmet medical needs in cancer reported that it has been invited to present at the DNB Nordic Healthcare Conference 2021, an Oslo based online event hosted by DNB (Press release, PCI Biotech, DEC 14, 2021, View Source [SID1234597416]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

On Thursday, 16 December 2021 at 11:10 (CET), Dr. Per Walday, CEO, will present an overview of PCI Biotech’s proprietary platform technology via a general company presentation. The Company is also available for 1:1 meetings with potential partners and investors.

The presentation slides will be made available on PCI Biotech’s website (www.pcibiotech.com) under "Other presentations".

BeiGene Announces Closing of Its RMB22.2 Billion (US$3.5 Billion) Initial Public Offering on the STAR Market of the Shanghai Stock Exchange in China

On December 14, 2021 BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global, science-driven biotechnology company focused on developing innovative and affordable medicines to improve treatment outcomes and access for patients worldwide, reported that it has completed its previously announced initial public offering (STAR Offering) on the Science and Technology Innovation Board (STAR Market) of the Shanghai Stock Exchange (SSE) (Press release, BeiGene, DEC 14, 2021, View Source [SID1234597276]). The shares offered in the STAR Offering were issued to and subscribed for by permitted investors in the People’s Republic of China (PRC) in Renminbi (RMB Shares). The RMB Shares began trading on the STAR Market under the stock code "688235" on December 15, 2021, China time, making BeiGene the first triple-listed biotechnology company on NASDAQ, the Hong Kong Stock Exchange (HKEx), and the STAR Market.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The total number of shares offered in the STAR Offering is 115,055,260 ordinary shares, par value $0.0001 per share, which represents 8.62% of BeiGene’s total outstanding ordinary shares as of October 31, 2021, after giving effect to the shares offered. The public offering price of the RMB Shares is RMB192.60 per ordinary share, which equates to HK$234.89 per ordinary share and US$391.68 per American Depositary Share (ADS), based on an assumed exchange rate of RMB0.81996 to HK$1.00 and RMB6.3924 to US$1.00. Each ADS represents 13 ordinary shares.

The gross proceeds to BeiGene from the STAR Offering, before deducting underwriting commissions and other estimated offering expenses, are approximately RMB22.2 billion, or approximately US$3.5 billion, based on an assumed exchange rate of RMB6.3924 to US$1.00.

China International Capital Corporation Limited and Goldman Sachs Gao Hua Securities Company Limited acted as joint sponsors and joint bookrunners for the STAR Offering. J.P. Morgan Securities (China) Company Limited, CITIC Securities Co., Ltd. and Guotai Junan Securities Co., Ltd. acted as joint bookrunners for the STAR Offering.

BeiGene has granted China International Capital Corporation Limited a 30-day overallotment option for up to 17,258,000 additional RMB Shares. If the over-allotment option is fully exercised, the total number of shares offered in the STAR Offering will be 132,313,260 Shares, which represents 9.79% of BeiGene’s total outstanding ordinary shares as of October 31, 2021, after giving effect to the shares offered.

BeiGene expects to use the net proceeds from the STAR Offering to fund its research and clinical development, construction of its research and development centers and a manufacturing plant in China, sales and marketing force expansion in China, and for working capital and general corporate purposes.

In accordance with applicable PRC laws and regulations, the STAR Offering is conducted solely within the PRC and only to permitted investors who are eligible to participate in the STAR Offering in accordance with applicable PRC securities laws and regulations, and rules promulgated by the SSE and the China Securities Regulatory Commission (CSRC). The STAR Offering is conducted pursuant to a prospectus and other offering materials prepared by BeiGene in Chinese language and as approved by and registered with the SSE and the CSRC, which are only permitted to be used within the PRC. No part of the STAR Offering is intended to involve a public offering or sale of the RMB Shares into or in the United States or any other jurisdiction outside of the PRC. In addition, although the RMB Shares are of the same class and have the same rights as the Company’s existing ordinary shares listed on the HKEx, the RMB Shares will not be fungible with the ordinary shares listed on the HKEx or the Company’s ADSs representing its ordinary shares listed on the NASDAQ Global Select Market (NASDAQ), and in no event will any RMB Shares be able to be converted into ordinary shares listed on the HKEx or ADSs listed on NASDAQ, or vice versa.

An automatically effective shelf registration statement on Form S-3 was filed with the Securities and Exchange Commission (SEC) on May 11, 2020. A prospectus supplement relating to and describing the key terms of the STAR Offering was filed with the SEC and is available on the SEC’s website at www.sec.gov. The purpose of the prospectus supplement is to register all RMB Shares offered in the STAR Offering under the Securities Act of 1933, as amended (Securities Act) to ensure that the offer and sale of the RMB Shares, if any, to permitted investors who are U.S. persons (as defined in Regulation S under the Securities Act) in transactions outside the United States will not violate the registration requirements under Section 5 of the Securities Act.

This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities, nor shall there be any offer or sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction. This press release is being issued pursuant to, and in accordance with, Rule 134 under the Securities Act.