Zealand Pharma launches long-term incentive program for Zealand’s US based Corporate Management for 2021

On May 27, 2021 Zealand Pharma A/S ("Zealand") (NASDAQ: ZEAL) (CVR-no. 20 04 50 78), a biotechnology company focused on the discovery, development and commercialization of innovative peptide-based medicines, reported the implementation of a new share-based long-term incentive program for Zealand’s US based Corporate Management, in accordance with Zealand’s Remuneration Policy as adopted at the annual general meeting held on 15 April 2021 (Press release, Zealand Pharmaceuticals, MAY 27, 2021, View Source [SID1234580684]). Zealand implemented the new incentive program to align with selected biotech peers, and is intended to drive long-term performance, align management’s and employees’ interests with those of Zealand’s shareholders, and support the attraction, retention, and motivation of first-rate executive talent.

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Accordingly, Zealand has awarded 32,363 restricted stock units ("RSUs") and 97,090 performance stock units ("PSUs") to the Corporate Management (split of 75% PSUs and 25% RSUs) that are employed by the US entity. The 2021 RSU grants vest annually in equal tranches over three years (from May 27, 2021 to May 27, 2024).

With respect to the PSUs;

50% of the PSUs vest based upon certain predefined operational goals that are required for Zealand to meet its strategic plans (such as clinical development or regulatory goals), and

50% of the PSUs vest based upon certain pre-defined market-based goals that encourage share performance against comparable companies (such as total shareholder return performance against Nasdaq Biotechnology Index).

Depending on the level of fulfillment of the goals the PSUs may vest between 0% and 150%.

For the financial year 2021, the total value of any share-based remuneration, including both RSUs and PSUs, cannot exceed 325% for other members of the Corporate Management at the time of grant.

The number of granted RSUs or PSUs may be adjusted by the Board of Directors due to e.g. changes in Zealand’s share capital structure or other significant events, subject to obtaining a calculation made by Zealand’s auditor or an independent third party.

Vested RSUs or PSUs entitle the holder to receive shares in Zealand at no cost, provided the holder’s continued employment throughout the vesting period. Each vested RSU equals one share in Zealand while PSUs convert into a number of shares equal to between 0% to 150% of the PSUs, depending on the achievement of the performance targets.

The grant of RSUs and PSUs under this program will have an estimated fair market value of DKK 24.8 million, based on each RSU having a fair value of DKK 191.60. The value of the RSUs is determined as the closing price of the Company’s share on Nasdaq Copenhagen A/S the day prior to the grant.

The LTIP will have no dilution effect on Zealand’s shareholders since Zealand intends to use treasury shares to meet its obligations to deliver shares under the incentive program.

Equivalent programs for the Danish Corporate Management were disclosed in press release 28/2021 on 12 May 2021.

CorMedix Inc. to Present at the Jefferies Virtual Healthcare Conference

On May 27, 2021 CorMedix Inc. (Nasdaq: CRMD), a biopharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of infectious and inflammatory disease, reported that CorMedix management will present a corporate overview at the Jefferies Virtual Healthcare Conference taking place on June 1 – 4, 2021 (Press release, CorMedix, MAY 27, 2021, View Source [SID1234580683]).

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Jefferies Virtual Healthcare Conference
Date: Friday, June 4
Time: 11:30 am Eastern Time
Webcast: View Source

InDex Pharmaceuticals presents at Redeye Growth Day 2021

On May 27, 2021 InDex Pharmaceuticals Holding AB (publ) reported that CEO Peter Zerhouni will present the company at Redeye Growth Day 2021 on June 2 at 8.50 CET (Press release, InDex Pharmaceuticals, MAY 27, 2021, View Source [SID1234580682]). The presentation will be livestreamed and can be followed at View Source." target="_blank" title="View Source." rel="nofollow">View Source

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The presentation, which will be held in Swedish, will also be available afterwards on View Source, on the company’s page in Redeye Universe (www.redeye.se/company/index-pharmaceuticals), as well as on InDex’s website (www.indexpharma.com).

Understanding organoid morphology: a study to assess organoid size and cell count from 3D image analysis

On May 27, 2021 Cellesce reported that has carried out a study in collaboration with Cardiff University to assess organoid size and cell count from 3D image analysis (Press release, Cellesce, MAY 27, 2021, View Source [SID1234580680]). Whilst the improved predictive power of patient-derived organoids (PDOs) have the potential to replace 2D assays in drug discovery the challenge for organoid users is to fully extract, exploit and understand the increased complexity of 3D in vitro models. 3D image analysis may well provide a means to address that challenge.

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Many of the practical limitations have already been overcome by recent advances in microscopy, leading to improvements in 3D image resolution, speed of imaging, data acquisition and dedicated software for high-content, high throughput assays. This technology can be used to quantify changes in gross organoid morphology, such as size and shape and also detect subtle, cellular, drug-induced alterations. Multi-parametric, image-based analysis can lead to an understanding of the relationship between the morphology of 3D PDOs and the underlying cell biology Badder et al. 2020, PLOS ONE.

SOM Biotech to participate at the BIO International Convention 2021

On May 27, 2021 SOM Biotech reported its participation in the BIO International Convention 2021 on June 10th – 18th, that will take place digitally (Press release, SOM Biotech, MAY 27, 2021, View Source;utm_medium=rss&utm_campaign=som-at-the-bio-international-convention-2021 [SID1234580679]).

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Hosted by the Biotechnology Innovation Organisation, the event is the largest global event for the biotechnology industry that attracts the leading biotech companies, scientists, research institutions, advisors, and qualified investors, providing extensive networking and partnering platform to support innovation, investment, and value creation.

Raúl Insa, CEO of SOM Biotech highlights: "The BIO International Convention is a key event to meet high profile partners and investors to explore areas of common interest and foster drug development initiatives and innovation. SOM Biotech is achieving outstanding results with its proprietary AI- ligand-based drug discovery platform, which we´d like to share with investors and potential business partners. Our unique technology has enabled us to build a robust drug development pipeline for orphan/CNS drug candidates. The Convention is a great opportunity to engage in strong partnerships with pharma companies and to meet with qualified investors. We look forward to identifying and sharing new business opportunities with both to continue growing."