On November 23, 2021 Kura Oncology, Inc. (Nasdaq: KURA), a clinical-stage biopharmaceutical company committed to realizing the promise of precision medicines for the treatment of cancer, reported that Troy Wilson, Ph.D., J.D., President and Chief Executive Officer, is scheduled to participate in two upcoming virtual investor conferences (Press release, Kura Oncology, NOV 23, 2021, View Source [SID1234595979]):

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A fireside chat at the Evercore ISI 4th Annual HealthCONx Conference at 11:20 a.m. ET / 8:20 a.m. PT on November 30, 2021; and

A fireside chat at the JMP Securities Hematology and Oncology Summit at 2:20 p.m. ET / 11:20 a.m. PT on December 7, 2021.
Audio webcasts of the Evercore and JMP events will be available in the Investors section of Kura’s website at www.kuraoncology.com, with archived replays available following both events.

On November 23, 2021 Oncorus, Inc. (Nasdaq: ONCR), a viral immunotherapies company focused on driving innovation to transform outcomes for cancer patients, reported that President and Chief Executive Officer, Theodore (Ted) Ashburn, M.D., Ph.D., will participate in two upcoming virtual investor conferences (Press release, Oncorus, NOV 23, 2021, View Source [SID1234595978]):

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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33rd Annual Piper Sandler Virtual Healthcare Conference: A corporate presentation will be available on-demand starting Monday, November 22nd at 10:00 a.m. ET.
Evercore ISI 4th Annual HealthCONx Conference: Fireside chat on Wednesday, December 1st, 2021 at 4:45 p.m. ET.
A webcast of each conference presentation will be available under the Investors & Media section of Oncorus’ website at View Source A replay of the presentations will be archived on Oncorus’ site for 30 days following the event.

On November 23, 2021 Immunomic Therapeutics, Inc., ("ITI") a privately held clinical-stage biotechnology company focused on advancing its proprietary nucleic acid immunotherapy platform, reported an exclusive option to license or acquire a series of innovative technologies in the immuno-oncology space from iOncologi, Inc., ("iOi") (Press release, Immunomic Therapeutics, NOV 23, 2021, View Source [SID1234595977]).

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Preclinical studies led by iOi Co-Founders, Drs. Duane Mitchell and Catherine Flores, have demonstrated that resistance to immune checkpoint inhibitors (ICIs) can be overcome by iOi’s novel, intravenously delivered stem cell-based therapeutic. Rapid translation of this possible breakthrough discovery into first-in-human clinical trials is underway. ITI’s option offers potential opportunities for both companies to further facilitate clinical and commercial development in the field of cell therapy and for collaboration in the development of nucleic acid vaccines that complements ITI’s own UNITE technology. The option agreement contemplates additional investment by ITI dependent upon iOi achieving certain clinical trial milestones.

"We are pleased to expand our collaboration with Dr. Duane Mitchell, both in his role as Founder & President of iOncologi, and as a leading academic researcher in the immuno-oncology field. Dr. Mitchell has been instrumental in the development and leadership of our ATTAC-II clinical trial for patients with Glioblastoma," said Dr. William Hearl, CEO of Immunomic Therapeutics. "His determination to bring innovative treatments to patients is what compounds the complementary technologies in both companies."

"We are very excited to have iOncologi and Immunomic Therapeutics bring together complementary expertise in the advancement of new treatments for patients with refractory cancers," said Dr. Mitchell. "This agreement expands upon a longstanding and very fruitful collaboration with Dr. Hearl and the team at ITI in bringing forward novel immunotherapy treatments for patients with Glioblastoma. I look forward to the advances that will come from this agreement between the two companies."

On November 23, 2021 SpringWorks Therapeutics, Inc. (Nasdaq: SWTX), a clinical-stage biopharmaceutical company focused on developing life-changing medicines for patients with severe rare diseases and cancer, reported that management will participate in a Fireside Chat at the 4th Annual Evercore ISI HealthCONx Conference, taking place virtually on Tuesday, November 30, 2021, at 3:30 pm ET (Press release, SpringWorks Therapeutics, NOV 23, 2021, View Source [SID1234595975]).

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A video webcast will be available on the Events & Presentations page within the Investors & Media section of the company’s website at View Source A replay of the webcast will be available on SpringWorks’ website for a limited time following the conference.

On November 23, 2021 Carrick Therapeutics, an oncology-focused biopharmaceutical company discovering and developing highly differentiated therapies, reported two presentations at the 2021 San Antonio Breast Cancer Symposium (SABCS), to be held from December 7-10, 2021 (Press release, Carrick Therapeutics, NOV 23, 2021, View Source [SID1234595974]).

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Abstracts are available starting on Friday, November 19, 2021, at 8:00am CT (9:00am ET/2:00pm GMT). The Company will participate in Poster Session 1 on Wednesday, December 8, 2021, from 7:00am-8:30am CT (8:00am-9:30am ET/1:00pm-2:30pm GMT) and provide an oral presentation on Thursday, December 9, 2021, at 11:00am CT (12:00pm ET/5:00pm GMT).

"We are excited to present additional data from our on ongoing clinical studies of Samuraciclib in HR+, HER2- advanced breast cancer and triple negative breast cancer at SABCS in December," said Dr. Stuart Mcintosh, Chief Medical Officer of Carrick Therapeutics. "The updated data being presented will speak to the clinical activity and tolerability seen to date in the trials. We are encouraged by the progress we’ve seen in both diseases, particularly for the TP53 wildtype sub-population within the broader HR+, HER2- trial, which will be discussed in further detail during the conference."

Poster and oral presentation details are as follows:

Poster Presentation Title: A clinical study of Samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in patients with advanced triple negative breast cancer (TNBC)
Presenting Author: Dr Sacha Howell
Abstract number: P1-18-10

Oral Presentation Title: Study of samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in combination with fulvestrant in patients with advanced Hormone Receptor positive HER2 negative breast cancer (HR+BC)
Presenting Author: Professor Charles Coombes
Abstract number: ID: GS3-10

About Samuraciclib (CT7001)
Samuraciclib is the most advanced oral CDK7 inhibitor in clinical development. Inhibiting CDK7 is a promising therapeutic strategy in cancer as CDK7 regulates the transcription of cancer-causing genes, promotes uncontrolled cell cycle progression and resistance to anti-hormone therapy. Samuraciclib has demonstrated a favorable safety profile and encouraging efficacy in early clinical studies. In addition to the above study, it is currently being evaluated in triple negative breast cancer (TNBC) and prostate cancer with further potential in pancreatic, ovarian and colorectal cancers. Samuraciclib has been granted Fast Track designations from the U.S. Food and Drug Administration (FDA) for use in combination with fulvestrant for the treatment of CDK4/6i resistant HR+, HER2- advanced breast cancer and in combination with chemotherapy for the treatment of locally advanced or metastatic TNBC.