Replimune to Present at the 39th Annual J.P. Morgan Healthcare Conference

On January 6, 2021 Replimune Group, Inc. (NASDAQ: REPL), a biotechnology company developing oncolytic immuno-gene therapies derived from its Immulytic platform, reported that Philip Astley-Sparke, Chief Executive Officer of Replimune, will present at the 39th Annual J.P. Morgan Healthcare Conference being held virtually on Tuesday, January 12, 2021 at 5:20 PM ET (Press release, Replimune, JAN 6, 2021, View Source [SID1234573531]).

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A simultaneous webcast will be available in the Investors section of Replimune’s website at www.replimune.com. A replay will be available for 30 days following the conference.

Investor Presentation dated January 6, 2021

On January 6, 2021, Immatics N.V. (the "Company") presented the Corporate Presentation (Presentation, Immatics, JAN 6, 2021, View Source [SID1234573530]).

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Revitope Oncology Announces Strategic Collaboration with Janssen to Leverage its Unique T Cell Engager Platform

On January 5, 2021 Revitope Oncology Inc. (Revitope), a biotechnology company advancing a new class of precision cancer immunotherapies, reported that the company has entered into a collaboration with Janssen Biotech, Inc. ("Janssen"), one of the Janssen Pharmaceutical Companies of Johnson & Johnson, evaluating Revitope’s proprietary T cell engager technology platform to develop next generation bi-specific antibody therapies (Press release, Revitope Oncology, JAN 5, 2021, View Source [SID1234633660]). The agreement was facilitated by Johnson & Johnson Innovation.

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"We are excited to enter into this collaboration with Janssen and employ Revitope’s PrecisionGATE technology platform to advance the development of T cell engager therapies with the aim of delivering safer, more efficacious therapies to patients," said Steve Arkinstall, Ph.D., Chief Executive Officer, Revitope Oncology. "This marks our second collaboration in the last 6 months as we continue to accelerate the potential of our platform and generate more effective targeted cancer therapeutics."

Revitope’s proprietary Precision Guided Antibody Tumor Engager (PrecisionGATE) technology platform exploits co-expressed tumor antigens to enable the development of highly specific cancer drugs with improved safety and efficacy over conventional immunotherapeutic approaches. The company’s unique approach combines a pair of tumor-targeted antibodies with a shared silent T cell engaging domain that become active only when they encounter cancer cells co-expressing both antigens. This allows for highly selective dual-antigen targeting to elicit and focus a powerful gated immune response to tumor cells.

Under the terms of the collaboration, Revitope will collaborate with Janssen to conduct a feasibility study in the evaluation of Revitope’s PrecisionGATE T cell engager platform.

leading independent proxy advisory firm iss recommends bridgebio pharma and eidos therapeutics stockholders vote “for” proposed merger

On January 5, 2021 BridgeBio Pharma, Inc. (Nasdaq: BBIO) reported that leading proxy advisory firm Institutional Shareholder Services ("ISS") recommends that BridgeBio stockholders and Eidos Therapeutics, Inc. (Nasdaq: EIDX) stockholders vote "FOR" BridgeBio’s proposed merger with Eidos and each of the other proposals to be considered at both companies’ virtual special meetings to be held on January 19, 2021 (Press release, BridgeBio, JAN 5, 2021, View Source [SID1234576236]).

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Under the proposed merger agreement, BridgeBio has agreed to acquire all of the outstanding common stock of Eidos it does not already own, representing approximately 36.3% of Eidos’ outstanding shares. Eidos stockholders will have the right to receive in the transaction, at their election, either 1.85 shares of BridgeBio common stock or $73.26 in cash per Eidos share in the transaction, up to an aggregate maximum of $175 million of cash. Based on the closing price of $71.11 per share of BridgeBio common stock on the Nasdaq on December 31, 2020, the stock consideration represented approximately $131.55 per share of Eidos common stock.

The BridgeBio board of directors unanimously recommends that BridgeBio stockholders vote "FOR" the proposal to approve the issuance of BridgeBio shares in connection with the merger agreement.

In light of the fact that BridgeBio owns a majority of the issued and outstanding Eidos common stock and certain BridgeBio officers and directors also serve on the Eidos board, the Eidos board formed a special committee of independent directors (the "Eidos special committee") to consider and negotiate the terms and conditions of the merger and to make a recommendation to the Eidos board. The Eidos special committee recommends that Eidos stockholders vote "FOR" the proposal to approve the merger with BridgeBio as well as additional proposals to be considered at the Eidos special meeting.

The merger is expected to be consummated by the end of the first calendar quarter of 2021, subject to the receipt of the required approvals from both BridgeBio and Eidos stockholders and other customary closing conditions. Following the consummation of the merger, Eidos will become a wholly owned subsidiary of BridgeBio and Eidos’ common stock will no longer be listed on any public market.

Revolution Medicines to Provide R&D Pipeline Update, Including Progress of RAS(ON) Inhibitor Programs, During Presentation at 39th Annual J.P. Morgan Healthcare Conference

On January 5, 2021 Revolution Medicines, Inc. (Nasdaq: RVMD), a clinical-stage precision oncology company developing targeted therapies to inhibit frontier targets in RAS-addicted cancers, reported that Mark A. Goldsmith, M.D., Ph.D., chief executive officer and chairman, will deliver a corporate presentation as part of the 39th Annual J.P. Morgan Healthcare Conference (Press release, Revolution Medicines, JAN 5, 2021, View Source [SID1234575007]). The conference, which will take place January 11-14, 2021, is being conducted with a virtual format.

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As a centerpiece of the update, Dr. Goldsmith will announce the entry of two first-in-class RAS(ON) Inhibitor programs into IND-enabling development and will discuss the profiles of these development candidates and next steps for advancing them. Dr. Goldsmith will also provide an update on the company’s three RAS Companion Inhibitors, including RMC-4630 (SHP2 inhibitor), RMC-5552 (mTORC1-selective inhibitor), and a new member, RMC-5845 (SOS1-selective inhibitor).

Details of Revolution Medicines’ presentation are as follows:

39th Annual J.P. Morgan Healthcare Conference
Conference Date: January 11-14, 2021
Presentation Time/Date: 5:20 p.m. Eastern on Tuesday, January 12, 2021
Format: Virtual conference; webcast available
To access the live webcast of the presentation, please visit the "Events & Presentations" page within the Investors section of Revolution Medicines’ website at View Source Additionally, a replay of the webcast will be available on the "Events & Presentations" page of the Revolution Medicines’ website for at least 14 days following the conference.