On January 11, 2022 Nascent Biotech, Inc. (OTCQB:NBIO) ("Nascent Biotech", "Nascent", or the "Company"), a clinical-stage biotechnology Company pioneering the development of monoclonal antibodies targeting treatment of various cancers and viral infections, reported the completion of dosing of the second cohort of patients involved in the Company’s Phase I trial to evaluate Pritumumab ("PTB") as a treatment for Brain Cancer, including Malignant Primary Brain Tumors and adult Brain Metastases (Press release, Nascent Biotech, JAN 11, 2022, View Source [SID1234598578]).
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
"After reviewing data gathered from the first and second cohorts, this milestone will allow us to quickly advance to our third cohort in the study, which is anticipated to start this month," noted Nascent CEO, Sean Carrick.
PTB is a natural human antibody that works by binding to Cell surface Vimentin (also referred to as ectodomain vimentin, or EDV), a protein expressed on the surface of epithelial cancers. PTB is used as a targeted immunotherapy that, unlike chemotherapy, only targets cancer cells without damaging healthy cells.
Carrick continued, "Having successfully completed the first two cohorts associated with this important trial, we are excited to move to our third escalation. Our rapid progress to this stage, and the positive data trends we have seen in the course of that process, moves us closer to petitioning for approval to begin Phase 2 testing."
Those interested in participating in the trial or finding out more information are invited to visit www.clinicaltrials.gov under the search term "Pritumumab".