On February 22, 2022 Poseida Therapeutics, Inc. (NASDAQ: PSTX), a clinical-stage biopharmaceutical company utilizing proprietary gene engineering platform technologies to create cell and gene therapeutics with the capacity to cure, reported that Brent Warner has joined the Company as President, Gene Therapy effective February 21, 2022 (Press release, Poseida Therapeutics, FEB 22, 2022, View Source [SID1234608823]).

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"Brent brings deep pharmaceutical expertise and a strong track record of leadership in gene therapy and rare genetic diseases to Poseida, and I am excited to welcome him to our team," said Mark Gergen, Chief Executive Officer of Poseida. "Alongside our top scientists, he will lead the execution of drug development programs in gene therapy, including our recent research collaboration with Takeda. It’s an exciting time at Poseida, and I look forward to working with Brent as we continue to advance our innovative gene therapy programs."

Mr. Warner has more than 15 years of biotech and pharmaceutical experience, most recently serving as Vice President, Gene Therapy and Rare Disease at Novartis, where he was responsible for building a division to commercialize multiple gene therapies overseeing three therapeutic areas. Prior roles included serving as a U.S. commercial leader in Hemophilia A at BioMarin Pharmaceutical Inc. and a variety of strategic operational roles at Biogen. Before that, he held commercial launch roles in blood disorders at Baxalta, then a biopharmaceutical division spun off by Baxter International and now a wholly owned subsidiary of Takeda. Warner has an MBA with an emphasis in marketing and finance and a Bachelor of Business Administration degree, both from Northwood University in Midland, Mich.

"I am thrilled to join Poseida, which has built an unparalleled platform to deliver novel cell and gene therapies for patients with high unmet need," Warner said. "Together with Poseida’s outstanding team, I look forward to the opportunity to accelerate potential single-treatment cures for the rare disease community."

On February 22, 2022 Neoleukin Therapeutics, Inc., "Neoleukin" (NASDAQ:NLTX), a biopharmaceutical company utilizing sophisticated computational methods to design de novo protein therapeutics, reported , reported it will report full year 2021 financial results on Tuesday, March 1, 2022 after the close of financial markets and then host a conference call and live audio webcast to discuss these results and provide a corporate update (Press release, Neoleukin Therapeutics, FEB 22, 2022, View Source [SID1234608822]). Details of the event are as follows:

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The archived audio webcast will be available on the Investor Relations section of the Neoleukin website approximately two hours after the event and will be available for replay for at least 30 days after the event.

On February 22, 2022 Kiniksa Pharmaceuticals, Ltd. (Nasdaq: KNSA) (Kiniksa), a biopharmaceutical company with a portfolio of assets designed to modulate immunological pathways across a spectrum of diseases, and Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., a wholly-owned subsidiary of Huadong Medicine Co., Ltd. (Huadong Medicine), reported a strategic collaboration to develop and commercialize Kiniksa’s ARCALYST and mavrilimumab in the Asia Pacific Region (Press release, Kiniksa Pharmaceuticals, FEB 22, 2022, View Source [SID1234608820]).

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"This collaboration aims to bring Kiniksa’s therapeutics to patients in the Asia Pacific Region suffering from severe autoimmune and inflammatory diseases. With extensive regional experience, proven development and regulatory execution, and deep relationships with a broad network of hospitals and clinics, Huadong Medicine is an ideal partner to help drive value," said Sanj K. Patel, Chairman and Chief Executive Officer of Kiniksa. "The collaboration also provides non-dilutive capital, cost-sharing, and resources for clinical trials to accelerate our drug development and commercialization efforts."

"Kiniksa is an emerging leader in the development of immune-modulating therapies, for which there is significant unmet need across the Asia Pacific Region," said Liang Lv, Chairman and CEO of Huadong Medicine. "In addition to ARCALYST, the first and only FDA-approved treatment for recurrent pericarditis, the compelling clinical data generated to-date for mavrilimumab provide foundational support for development across a range of underserved diseases. We look forward to working closely with Kiniksa to leverage our clinical, regulatory, and commercial capabilities in the Asia Pacific Region."

Under the terms of the collaboration, Kiniksa will receive $22 million upfront and is eligible to receive up to approximately $640 million in specified development, regulatory and sales-based milestones. Kiniksa is also eligible to receive tiered royalties ranging from the low-teens to the low-twenties on annual net sales. Huadong Medicine will obtain exclusive rights and responsibility for the development and commercialization of ARCALYST and mavrilimumab in the Asia Pacific Region including Greater China, South Korea, Australia, and 18 other countries, but excluding Japan. Kiniksa will otherwise retain all existing development and commercialization rights for both assets.

On February 22, 2022 Bio-Techne Corporation (NASDAQ: TECH) reported an agreement with Thermo Fisher Scientific to exclusively complete development of and commercialize the ExoTRU kidney transplant rejection test developed by Exosome Diagnostics, a Bio-Techne brand (Press release, Bio-Techne, FEB 22, 2022, View Source [SID1234608818]).

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ExoTRU is a non-invasive multigene urine based liquid biopsy assay that provides critical allograft health information to assist clinician decision making in managing kidney transplant patients and optimizing patient care. The assay has the potential to discriminate between T-cell mediated rejection (TCMR) and antibody mediated rejection (ABMR), which is critical to improving patient management and outcomes. ExoTRU was developed in collaboration with the Azzi Laboratory at the Transplantation Research Center at Brigham and Women’s Hospital, Harvard Medical School.

"We continue to demonstrate the utility of exosomes as a source of significant clinical value for non-invasive testing. ExoTRU is another great example of this potential, with this assay filling a significant unmet need in the area of kidney transplant patient care," commented Kim Kelderman, President of Bio-Techne’s Diagnostics and Genomics Segment. "Thermo Fisher is the ideal partner to complete development of and commercialize ExoTRU, with its trusted reputation and established transplant center relationships creating the ideal channel to drive awareness and adoption of this best-in-class assay."

"We see tremendous potential for ExoTRU to improve the care offered to kidney transplant patients and scale into a market leading liquid biopsy test," said John Sos, Senior Vice President and President, Specialty Diagnostics at Thermo Fisher Scientific. "We look forward to partnering with Bio-Techne to bring this important innovation to market.

On February 22, 2022 Viewpoint Molecular Targeting, Inc. ("Viewpoint" or the "Company"), a precision oncology company developing alpha-particle therapies and complementary diagnostic imaging agents, reported that Thijs Spoor, Chief Executive Officer of Viewpoint, will participate in a fireside chat at the B. Riley Radiation Oncology Investor Day today, February 22, 2022 at 1:30 PM ET (Press release, Viewpoint Molecular Targeting, FEB 22, 2022, https://viewpointmt.com/viewpoint-molecular-targeting-to-present-at-the-b-riley-radiation-oncology-investor-day/ [SID1234608817]).

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The B. Riley Securities Radiation Oncology Investor Day, being held virtually on Tuesday, February 22nd, is designed to provide insights into the current state and future direction of the radiation oncology field by bringing together innovative companies and independent experts. The event features fireside chats with key public and private companies working in the space as well as an expert KOL panel discussion. Topics are expected to range from understanding and overcoming supply chain and logistical challenges unique to radiopharmaceuticals, to the potential competitive and/or complementary roles of external beam and targeted radiotherapies.

To register and for more information about the event, please visit the event website.