On May 19, 2022 Inceptor Bio, a biotechnology company advancing cell therapies for difficult-to-treat cancers, reported the closing of a $37 million Series A financing led by Kineticos Ventures (Press release, Inceptor Bio, MAY 19, 2022, View Source [SID1234614862]).

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Proceeds from the Series A financing will be used to advance Inceptor Bio’s CAR-T lead program to a Phase I clinical trial and continue development of its CAR-M and CAR-NK platforms. Additionally, proceeds will support completion of Inceptor Bio’s Advanced Manufacturing Platform (AMP+) facility, a 29,000 square foot, state-of-the-art cell and gene therapy GMP manufacturing site located in Gainesville, Florida.

Inceptor Bio’s CAR-T, CAR-M, and CAR-NK platforms are at the center of a diversified portfolio of cell therapies focused on novel mechanisms that enhance cell performance in the tumor microenvironment. Novel technologies include a co-stimulatory domain M83, proprietary TMax manufacturing process, the K62 platform, which increases the phagocytic capabilities of macrophages and supports a M1 anti-tumor phenotype, and a differentiated iPSC technology.

"We are grateful for the continued support of Kineticos Ventures and our life sciences investors," said Shailesh Maingi, Founder and CEO of Inceptor Bio. "We have a simple strategy at Inceptor Bio. We’re advancing novel CAR-T, CAR-M and CAR-NK platforms into the clinic, securing our supply through AMP+, and building a leading team of scientists and engineers in order to improve treatment options for patients with difficult-to-cancers."

"This Series A funding allows us to focus on advancing our lead CAR-T program into the clinic while continuing to advance our other exciting cell therapy platforms," said Mike Nicholson, Ph.D., President and Chief Operating Officer of Inceptor Bio. "Our programs address serious challenges in the cell therapy arena, and fully realizing the potential of these therapies requires significant capital. We are grateful for the support of this incredible group of investors."

"Investing in early life sciences companies with promising pipelines like Inceptor Bio is at the heart of what we do," said Frank Lis, President of Kineticos Ventures. "With an expert team and a scalable manufacturing facility, Inceptor Bio is well positioned to advance next-generation cell therapy technologies to address difficult-to-treat cancers."

On May 19, 2022 The European Organisation for Research and Treatment of Cancer (EORTC) reported its continued partnership with Alliance Healthcare, one of the largest pharmaceutical wholesalers in Europe (Press release, EORTC, MAY 19, 2022, View Source [SID1234614861]). Specifically, the collaboration supports the organisation’s SPECTA platform, a pan-European translational research infrastructure for all tumour types including rare cancers.

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The EORTC SPECTA platform allows for the rapid implementation of new clinical trials and robust translational cancer research aimed at increasing our understanding of cancers in order to guide a more targeted clinical research and treat patients effectively.

Alliance Healthcare was previously owned by Walgreens Boots Alliance (WBA) until June 2021. Since then, Alliance Healthcare is a wholly owned subsidiary of AmerisourceBergen and the EORTC is delighted that its support and commitment to SPECTA is to continue under this new ownership. The fantastic support that Alliance Healthcare as part of WBA has provided over the past 10 years (since 2011) will persist to further reinforce and strengthen recognition of the SPECTA platform as the leading pan-European translational research infrastructure. The partnership with Alliance Healthcare under the umbrella of AmerisourceBergen will ensure the continuation of SPECTA’s work in personalised cancer medicine, helping guide patients’ treatments, but also advance our understanding of cancer biology to help treat more patients effectively.

Through the growth of SPECTA’s translational clinical research, it provides hope to thousands of patients. One patient with papillary thyroid cancer said that their "current treatment was defined after [their] inclusion in SPECTA" and after previous treatments didn’t work.

Treating oncologists also benefit from SPECTA. Pr. Jean-Yves Blay has said "the SPECTA study enables [the opportunity] to gain more understanding on the nature of the disease and to guide the treatment of many patients with rare cancer, which is quite unique."

Today, SPECTA’s ever-growing cancer clinical research platform includes 128 authorized research doctors in 17 countries. More than 1330 patients have participated in 3 clinical research projects with over 1200 individual result reports provided to patients and providing guidance for their treatment.

EORTC CEO, Dr Denis Lacombe commented "EORTC looks forward to continue working with Alliance Healthcare and AmerisourceBergen, pushing the boundaries of understanding cancer and furthering the standard of care for cancer patients in the European continent, through SPECTA."

Juan Guerra, SVP Managing Director at Alliance Healthcare said "I am extremely proud of the efforts of Alliance Healthcare colleagues Europe-wide over the last decade. The work the EORTC does, and advancements in cancer therapies and treatment SPECTA brings about, is critical in the fight against this disease. I am extremely happy that under our new AmerisourceBergen ownership we are continuing to help and support through a range of fund-raising initiatives and a donation from the AmerisourceBergen Foundation as together we aim to improve the health and wellbeing of patient populations."

On May 19, 2022 EpiAxis Therapeutics reported to attend and present at the 16th Bioshares Biotech Summit this month in Albury, NSW (Press release, EpiAxis Therapeutics, MAY 19, 2022, View Source;utm_medium=rss&utm_campaign=epiaxis-therapeutics-presents-bioshares-biotech-summit [SID1234614860]).

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BioShares is a life science conference mainly targeting ASX-listed Australian biotech companies, biotech investors, fund managers and brokers and entrepreneurs. The conference was organised by Bioshares, Australia’s leading independent biotech investment publication.

The event featured an intense two-day program, with approximately 25 speakers and excellent networking opportunities within the biotech industry and investment sectors. It was a valuable opportunity to access to investors who support the Australian life science sector.

EpiAxis was represented at Bioshares by Chairman Dr David Fuller, Director Rob McInnes and CEO Dr Jeremy Chrisp. Dr Chrisp gave a presentation during the "New Kids on the Block" session on day two of the conference.

Dr Fuller said: "It was great to see Bioshares return and be face-to-face with industry colleagues and friends again after the COVID-19 pandemic. The EpiAxis presentation was well received and marked the start of our next fundraising effort, with discussions held with many of the investors and funds present."

On May 19, 2022 ChromaDex Corp. (NASDAQ:CDXC) ("the Company") a global bioscience company dedicated to healthy aging, reported it has entered into an agreement (the "JV Agreement") to establish a joint venture through its wholly owned subsidiary ChromaDex Asia Limited (the "JV" or "ChromaDex Asia") (Press release, ChromaDex, MAY 19, 2022, View Source [SID1234614859]). Upon establishment of the JV, membership of ChromaDex Asia will collectively consist of the Company; Crystal Lake Developments Limited; Pioneer Idea Holdings Limited; and Hong Kong Taikuk (China) Group Limited. ChromaDex Asia is expected to assume the distribution agreement noted in a previous announced press release with Sinopharm Xingsha ("Sinopharm") as it relates to the commercialization of Tru Niagen in mainland China and its territories, excluding Hong Kong, Macau and Taiwan (the "Territory"). The JV’s entry into a distribution agreement will be contingent upon Sinopharm successfully attaining health food product registration for Tru Niagen with the People’s Republic of China’s State Administration for Market Regulation ("SAMR"). SAMR is the regulatory body responsible for health food registration. Health food registration is a key regulatory step required to be able to broadly market and distribute Tru Niagen products in China. Formation of the joint venture is subject to customary closing conditions.

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"The establishment of this joint venture marks an expansion milestone in ChromaDex’s China strategy and sets the necessary foundation to advance sales of Tru Niagen in this key market," said Rob Fried, CEO of ChromaDex. "We are honored to extend our professional relationship with existing strategic partners, as well as our new partner in this venture, Taikuk."

For detailed transaction terms, see 8-K (filed on May 19, 2022).

On May 19, 2022 Abeona Therapeutics Inc. (Nasdaq: ABEO), a fully-integrated leader in cell and gene therapy, reported that the Company has been granted an additional 180-day period from Nasdaq’s Listing Qualification Department, through November 14, 2022, to regain compliance with the $1.00 minimum bid price requirement for continued listing on The Nasdaq Capital Market (Press release, Abeona Therapeutics, MAY 19, 2022, View Source [SID1234614856]). The Company’s common stock continues to trade on the Nasdaq Capital Market under the symbol "ABEO."

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If at any time until November 14, 2022, the closing bid price of the Company’s common stock is at or above $1.00 per share for a minimum of 10 consecutive trading days, Nasdaq will provide the Company with written confirmation of compliance. If compliance cannot be demonstrated during the additional 180-day grace period, Nasdaq will provide written notification that the common stock will be subject to delisting. At such time, the Company may appeal the determination to a Nasdaq Hearings Panel. The Company’s common stock would remain listed pending the completion of the appeal process.

As part of the Company’s strategy to regain compliance with Nasdaq’s minimum bid price requirement, Abeona intends to seek approval of a reverse stock split of the outstanding shares of common stock at a Special Meeting of stockholders at 10:00 am ET on June 14, 2022. Stockholders as of May 3, 2022, the record date, are entitled to attend the online Special Meeting, view the proxy statement and vote at: www.virtualshareholdermeeting.com/ABEO2022SM.