Veracyte to Release Third Quarter 2022 Financial Results on November 2, 2022

On October 13, 2022 Veracyte, Inc. (Nasdaq: VCYT) reported that it will release financial results for the third quarter of 2022 after the close of market on Wednesday, November 2, 2022 (Press release, Veracyte, OCT 13, 2022, View Source [SID1234622019]). Company management will host a conference call and webcast to discuss financial results and provide a general business update at 4:30 p.m. Eastern Time on the same day.

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The conference call will be webcast live from the company’s website and will be available via the following link: View Source A webcast replay will be available following the conclusion of the live broadcast and will be accessible on the company’s website at View Source

The conference call dial-ins can be accessed by registering at: https://register.vevent.com/register/BIdd8a25033ce74acb8bf03d2ed76733f0

Odyssey Therapeutics Announces Oversubscribed $168 Million Series B Financing

On October 13, 2022 Odyssey Therapeutics, Inc., a biotechnology company pioneering next generation precision immunomodulators and oncology medicines, reported a $168 million Series B financing (Press release, Odyssey Therapeutics, OCT 13, 2022, View Source [SID1234622016]). This funding, which follows Odyssey’s $218 million Series A announced in December 2021, brings the total capital raised to $386 million. The proceeds will enable Odyssey to advance its portfolio of precision immunomodulators and oncology medicines in support of its mission of developing innovative medicines to treat serious human diseases.

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The Series B was led by General Catalyst, a leading global venture capital firm and active investor in the healthcare sector. Other new investors participating in the Series B financing include funds and accounts advised by Fidelity Management & Research Company, funds and accounts advised by T. Rowe Price Associates, Inc., GreatPoint Ventures, Catalio Capital Management, Walleye Capital, Alexandria Venture Investments, The Healthcare Innovation Investment Fund LLC, an investment fund associated with SVB Securities LLC, and other institutional investors. The financing also includes participation from all Series A investors including OrbiMed, SR One, Foresite Capital, Logos Capital, Woodline Partners LP, HBM Healthcare Investments, Colt Ventures and Creacion Ventures.

"Odyssey is pioneering next generation therapeutics by marrying a powerful drug discovery engine integrating machine learning, biology, and medicinal and structural chemistry with an exceptional leadership team of proven drug developers. We are pleased to partner with General Catalyst and our world-class syndicate of investors and believe the interest in our immunology and oncology pipeline and capabilities further validates our approach to therapeutic development," said Gary D. Glick, Ph.D., Founder and Chief Executive Officer of Odyssey Therapeutics. "We have made tremendous strides since our launch in 2021, and we value the support as we advance multiple candidates into IND-enabling studies in 2023."

"At General Catalyst, we are committed to investing in companies driving powerful, positive and enduring change, and Odyssey’s unyielding commitment to improving the lives of patients by targeting the underlying causes of serious inflammatory diseases and cancer aligns with our mission," said Elena Viboch, Partner at General Catalyst. "We are confident in Odyssey’s vision, proven leadership and ability to pioneer and develop next generation therapeutics through their integrated platform approach, and we look forward to seeing Odyssey work toward achieving their mission of delivering life-enhancing medicines to patients in need."

"I am delighted to welcome our new Series B investors," said Jeff Leiden, M.D., Ph.D., Chairman of the Odyssey Board. "Their investment along with Odyssey’s unique combination of experienced and talented drug hunters, new technologies and a broad and deep pipeline of novel targets will accelerate our discovery and development of life-enhancing medicines for patients in need."

Odyssey’s immunology and oncology portfolio encompasses eight declared programs initially focused on small molecule and protein therapeutics. In addition, Odyssey is building an industry leading discovery engine that integrates artificial intelligence and machine learning for molecular design; a chemistry platform encompassing proprietary covalent libraries targeting multiple amino acids, molecular glues and natural products; and a functional genomics platform for novel target discovery.

Harbour BioMed Announces Upcoming Poster Presentations at the 37th Society for Immunotherapy of Cancer Annual Meeting

On October 13, 2022 Harbour BioMed (the "Company", HKEX: 02142), a global biopharmaceutical company committed to the discovery, development, and commercialization of novel antibody therapeutics focusing on oncology and immunology, reported that the Company will present new preclinical data of five portfolio assets including HBM7008, HBM7004, HBM1047, HBM1020 and HBM1022 in five poster presentations at the 37th Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)’s (SITC) (Free SITC Whitepaper) Annual Meeting in Boston, via in person/virtual attendance, November 8-12, 2022 (Press release, Harbour BioMed, OCT 13, 2022, View Source [SID1234622015]).

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List of the poster presentations:

Title: HBM1047, a novel fully human anti-CD200R1 antagonist antibody with potent anti-tumor efficacy in preclinical model
Abstract number: 477

Title: HBM7008 (B7H4x4-1BB HBICE) synergizes HBM7004 (B7H4xCD3 HBICE) for solid tumor therapy
Abstract number: 858

Title: HBM7008, a first-in-class bispecific antibody targeting both B7-H4 and 4-1BB, exhibits robust anti-tumor immunity and low toxicity through B7-H4-directed 4-1BB activation
Abstract number: 1057

Title: HBM1020 is a fully human novel anti-B7H7 antibody with excellent preclinical efficacy and safety profile
Abstract number: 1075

Title: HBM1022: an afucosylated anti-CCR8 antibody, depletes specifically tumor infiltrating Tregs and inhibits tumor growth with excellent safety profile in preclinical studies
Abstract number: 1361

More details about the SITC (Free SITC Whitepaper) Annual Meeting are available on the official website. Full text of the abstracts will be made public on November 7, 2022, 8:00 a.m. EST. All posters will be presented on Thursday, November 10-11, 2022, from 9:00 a.m. to 9:00 p.m. EST, in the Boston Convention & Exhibition Center, Exhibit Hall C.

Palatin Announces Preliminary First Quarter Fiscal 2023 Vyleesi® Product Sales Results

On October 13, 2022 Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of the melanocortin receptor system, reported preliminary first quarter fiscal year 2023 Vyleesi product sales results (Press release, Palatin Technologies, OCT 13, 2022, View Source [SID1234622014]). Vyleesi is the first and only as-needed treatment approved by the U.S. Food and Drug Administration (FDA) for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD).

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"We are pleased with Vyleesi’s continued quarter over quarter growth on net product revenue and prescriptions dispensed for the quarter ended September 30, 2022," stated Carl Spana, Ph.D., President and CEO of Palatin. "We are especially pleased with our prescription refill rate, which now exceeds 50% of total prescriptions dispensed, and is the top indicator of patient satisfaction with Vyleesi."

Preliminary Vyleesi product sales results for the first fiscal quarter of 2023 ended September 30, 2022:
Net product revenue for prescriptions dispensed increased 20% to $856,000 over the prior quarter;
increased 400% over the comparable quarter in fiscal 2022.
Total prescriptions dispensed increased 17% over the prior quarter;
increased 108% over the comparable quarter in fiscal 2022.
Preliminary Financial Information
The Vyleesi related financial and operating data for the first fiscal quarter of 2023 is preliminary and may change. This preliminary data has been prepared by, and is the responsibility of, Palatin’s management and no independent accounting firm has audited, reviewed, compiled, or performed any procedures with respect to this preliminary financial data. There can be no assurance that Palatin’s actual results for this quarterly period will not differ from the preliminary financial and operating data and such changes could be material. In addition, Palatin’s estimate of Vyleesi product sales for the quarter ended September 30, 2022 should not be viewed as a substitute for full financial statements prepared in accordance with U.S. generally accepted accounting standards. Additional information that will be material to investors will be provided in the financial statements for the three months ended September 30, 2022, and, accordingly, investors should not place undue reliance on the limited preliminary information being provided herein.

About Vyleesi (bremelanotide injection) for Hypoactive Sexual Desire Disorder (HSDD)
Vyleesi is the first and only as-needed treatment approved by the FDA for premenopausal women with acquired, generalized HSDD. Palatin is actively seeking Vyleesi collaborations for the United States and for territories outside the currently licensed territories of China and Korea. Vyleesi is licensed to Fosun Pharma in China and Kwangdong Pharmaceuticals in South Korea. Patients and healthcare providers can learn more about HSDD and Vyleesi at www.vyleesi.com and www.vyleesipro.com.

Tyra Biosciences to Present Preclinical Data on TYRA-200, an FGFR1/2/3 Inhibitor, at 34th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics

On October 13, 2022 Tyra Biosciences, Inc. (Nasdaq: TYRA), a precision oncology company focused on developing purpose-built therapies to overcome tumor resistance and improve outcomes for patients with cancer, reported that the Company will present preclinical data on TYRA-200 during a poster session at the 34th EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) Symposium on Molecular Targets and Cancer Therapeutics, taking place October 26-28, 2022, in Barcelona, Spain (Press release, Tyra Biosciences, OCT 13, 2022, View Source [SID1234622013]).

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Details of the poster presentation are as follows:

Title: TYRA-200: Potent Against FGFR2 Fusions, Molecular Brake Mutations and Gatekeeper Resistance
Date/Time/Location: Wednesday, October 26, 2022, 12-20:00 CET, Exhibition Hall
Session/Session Code: Molecular Targeted Agents 1, PP20
Poster #: 47

Regular abstracts are available on the EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) website. The poster on TYRA-200 will be made available on the TYRA website under the "For Investors" section on October 26, 2022.