ImmunityBio to Participate in the Jefferies London Healthcare Conference

On October 27, 2022 ImmunityBio, Inc. (NASDAQ: IBRX), a clinical-stage immunotherapy company, reported that the company will be presenting at the Jefferies London Healthcare Conference, which is taking place in London from November 15-17, 2022 (Press release, ImmunityBio, OCT 27, 2022, View Source [SID1234622475]).

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A replay of the presentation will be available by visiting the "Events" section of the ImmunityBio website and will be archived for 90 days.

Obsidian Therapeutics Announces Extension of Multi-Year Collaboration Agreement with Bristol Myers Squibb

On October 27, 2022 Obsidian Therapeutics, Inc., a clinical-stage biotechnology company pioneering engineered cell and gene therapies, reported that Bristol Myers Squibb (NYSE:BMY) has opted to extend the term of the parties’ multi-year strategic collaboration for the discovery and development of novel, regulated cell therapies that utilize Obsidian’s cytoDRiVE technology for the controlled expression of the immune enhancer CD40L (Press release, Obsidian Therapeutics, OCT 27, 2022, View Source [SID1234622474]). Today’s announcement builds on the existing relationship between Obsidian and Bristol Myers Squibb, initiated in 2019, and follows the first opt-in decision by Bristol Myers Squibb in 2020.

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"We are delighted to extend our productive strategic partnership with Bristol Myers Squibb, an industry leader in the field, to advance next-generation cell therapies to patients with solid tumors and other malignancies," said Paul K. Wotton, Ph.D., Chief Executive Officer of Obsidian Therapeutics. "This announcement comes at an exciting time for Obsidian as our own lead program using cytoDRiVE technology enters the clinic."

This multi-year collaboration extension provides Bristol Myers Squibb with the exclusive option to in-license worldwide rights for cell therapy candidates incorporating Obsidian’s cytoDRiVE technology to control the expression of CD40L for the treatment of cancer. Under the terms of the agreement, Obsidian is eligible to receive potential future milestone and royalty payments.

Prestige Biopharma attends 2022 Biosimilar Medicines Conference

On October 6, 2022 Prestige Biopharma Limited, a Singapore-based biopharmaceutical company, reported that the company is attending the 2022 Biosimilar Medicines Conference which takes place in Brussels, Belgium, on October 6 and 7 (Press release, Prestige BioPharma, OCT 27, 2022, View Source [SID1234622473]).

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The Biosimilar Medicines Conference by Medicines for Europe (MfE) aims to facilitate discussion on existing challenges and future opportunities for biosimilar medicine policy and pharmaceutical legislation. The MfE represents the pharmaceutical companies supplying the largest share of medicines across Europe. According to the association, its members currently supply over 67% of all medicines in Europe.

This year’s conference is held in person after three years since COVID-19 pandemic. Speakers and panellists will explore how to turn the Pharmaceutical Strategy aim to ensure better access and affordability into concrete biosimilar medicine policy measures.

At the conference, many former and current members of European Medicines Agency (EMA) will be speakers and address biosimilar medicine policies. Prestige Biopharma plans to actively engage in discussions on regulations and build network, while seeking opportunities for collaboration with major biopharmaceuticals in Europe.

Dr. Susanne Schmidt, Director of Alliance & Portfolio Management in Prestige Biopharma, will participate in the conference. Dr. Schmidt had served as Senior Director of Global/International Business Development at Pfizer and has 25 years of experience in the biopharmaceutical industry, working for multiple leading pharmaceuticals.

Dr. Schmidt commented: "The healthcare systems and policies in the European market vary from country to country. This conference, which brings together pharmaceutical experts from different countries in Europe, provides a good opportunity for in-depth study and understanding on the European market. We also plan to strengthen our presence in the European market by participating in more conferences held in individual European countries and introducing our pipeline portfolio and R&D results."

Monteris Medical Announces $73 Million in Combined Equity and Debt Financing

On October 27, 2022 Monteris Medical, a private medical technology company dedicated to becoming the technology leader in minimally invasive brain surgery, reported it has secured $73 million in financing including $35 million in new Series D equity and a $38 million debt facility (Press release, Monteris Medical, OCT 27, 2022, View Source [SID1234622472]). The equity financing was led by new investor, InnovaHealth Partners, and was supported by existing lead investor, Birchview Capital. The debt facility, provided by Madryn Asset Management, LP, extended $28 million at closing, with the option to draw an additional $10 million upon the achievement of certain milestones. The proceeds will be used to support important market adoption, clinical research and technology programs and will permit the company to refinance its current obligation.

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"Brain tumor and drug-resistant epilepsy patients and their physicians are looking for less invasive options when making their treatment decisions," said Martin J. Emerson, Monteris Medical’s president and chief executive officer. "NeuroBlate has been proven to offer a less invasive option for patients considering open brain surgery and is also a valuable minimally invasive tool to address surgical locations in the brain that are not accessible with more invasive traditional methods. The Monteris Medical team is pleased to add InnovaHealth and Madryn as financial partners, allowing us to further expand our efforts to bring the value of the NeuroBlate technology to more physicians and the patients we collectively serve."

The proceeds of this financing will be used to continue to support the rapid adoption of Monteris Medical’s NeuroBlate System, an MR-guided laser ablation system that allows for a minimally invasive surgical alternative to open craniotomies. The NeuroBlate System is currently installed in more than 100 hospitals in the United States and Canada and is actively used in minimally invasive treatment approaches for patients with drug-resistant epilepsy, primary and metastatic brain tumors, and radiation necrosis. These proceeds will also be used to continue ongoing clinical research, including exciting work in adjuvant immunotherapies, and technology advancement projects for the NeuroBlate System.

"Monteris Medical’s NeuroBlate technology and the company’s increasing depth of clinical evidence are transforming how physicians and their patients think about brain surgery. We are proud to support the expansion of this important technology," said Mortimer "Tim" Berkowitz III, InnovaHealth’s president and chief executive officer.

Lilly commits $92.5 million to Purdue to establish an innovative pharmaceutical manufacturing scholarship program and to extend research collaboration

On October 27, 2022 Purdue University and Eli Lilly and Company (NYSE: LLY) are establishing an innovative new pharmaceutical manufacturing scholarship program and have renewed their strategic research collaboration in a series of moves reported that that will expand their impact in Indiana and improve lives on a global scale (Press release, Eli Lilly, OCT 27, 2022, View Source [SID1234622471]). Lilly has committed $92.5 million to the West Lafayette campus through these two programs.

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Lilly’s commitment includes $42.5 million over 10 years to fund pharmaceutical manufacturing scholarships for incoming Purdue undergraduate students, offering 75-100 talented students each year full tuition with a guaranteed internship or co-op at Lilly and a promise of coordinated interaction with company leaders. Priority access to the new Lilly Scholars program will be given to undergraduate students who are underrepresented in Purdue’s student population, have overcome socioeconomic or educational disadvantages or are among the first generation in their family to attend college.

"Lilly is among Purdue’s most important partners, and this latest commitment reaffirms our longtime collaboration. Through these collaborations, Lilly and Purdue are helping to build a critical pharmaceutical ecosystem in the heartland," said Purdue President Mitch Daniels. "We have a company that is committed to advancing research and fostering talent. Lilly is investing in students very early in their education rather than waiting until late in their college careers – connecting to students before they even arrive on campus."

The Lilly Scholars program will provide participating students with preferred access and opportunities to compete for a role at the company following graduation. The first scholarships will be offered for fall 2023.

Purdue and Lilly have a historic relationship, dating back to the organizations’ founding years. The organizations entered into a new strategic research collaboration in 2017, funded by an initial $50 million commitment from Lilly. Those collaborative research efforts have helped advance understanding of the physiology of drug delivery and develop technologies to improve delivery of pharmaceuticals for better patient outcomes and experiences. Lilly and Purdue are now expanding that research collaboration, signing a new $50 million master agreement that extends the work for another five years, with a research focus on genetic medicine, intrathecal delivery and nanoparticle drug delivery.

"As the number of people who may benefit from our innovative medicines continues to increase, we are investing to advance critical research and build a more diverse pipeline of talent in Indiana. Together with Purdue, we can help to keep our state’s best and brightest in Indiana, furthering Lilly’s ability to make life better for millions of people," said David A. Ricks, Lilly’s chair and CEO. "As a Purdue graduate, I am proud of the success the university has built and even more proud to see Lilly and Purdue team up to make both institutions better and better."

The basic research by Purdue faculty helps Lilly expedite the development of technologies and pharmaceuticals, improving the pace of getting therapies to patients who need them. Over the last eight years, Lilly has introduced 18 new medicines to make life better for people living with diseases like diabetes and cancer. The company aims to introduce four additional potential new medicines in the next 18 months.

"Purdue’s approach to interdisciplinary research with Lilly is driven by an impact-focused mindset aimed at improving the lives of patients. Our collaboration spans training and development all the way to cutting-edge research and facilities," said Theresa Mayer, Purdue University executive vice president for research and collaboration. "The extension of our agreement will continue to provide exceptional opportunities for faculty members and hundreds of graduate students from across the country to work side-by-side with colleagues from this leading pharmaceutical company."

Both Lilly and Purdue have made strategic commitments in recent years to strengthen expertise and programs in bioscience areas, including pharmaceutical manufacturing.

Earlier this year, Purdue established the William D. Young Institute for Advanced Manufacturing of Pharmaceuticals, an interdisciplinary organization focused on furthering pharmaceutical manufacturing to reduce costs and expand access to new drugs emerging from biotech research. That institute follows a $250 million investment in life sciences as part of the Purdue Moves strategic plan, which resulted in three university-wide interdisciplinary institutes: the Purdue Institutes of Drug Discovery; Inflammation, Immunology and Infectious Disease; and Integrative Neuroscience, which have helped to attract leading faculty researchers in critical research areas. Purdue has also invested in state-of the-art facilities, including the Bindley Bioscience Center, which provides a unique infrastructure to support interdisciplinary research.

Over the last five years, Lilly has committed over $6 billion in pharmaceutical manufacturing globally. This includes $2.1 billion and up to 500 new jobs in the LEAP Technology Park in Boone County, Indiana, announced in May 2022, and up to 1,500 more jobs during construction of the site.

"Collaborations between academia and industry are essential to innovation to bring therapies to patients as quickly as possible," said Edgardo Hernandez, executive vice president and president of manufacturing operations at Lilly. "With the expansion of our footprint in Indiana, these initiatives with Purdue will help bring a highly skilled pipeline of diverse talent and enhance our manufacturing capacity to deliver medicines to patients around the world."

As Lilly and Purdue work together on new curricula, experiential learning, and certificate and degree programs in pharmaceutical manufacturing, they will help continue to grow pharmaceutical manufacturing in Indiana and expand Purdue’s talent pipeline to the company with students supported by the new scholarship program. Every year, Lilly hires Purdue graduates in areas such as engineering, sales, finance, human resources, marketing, procurement, supply chain and more. In fact, Lilly employs nearly 2,500 Purdue graduates – more than from any other university.

"These commitments will better position Purdue to recruit the best, brightest and most diverse students we can," said Kristina Wong Davis, vice provost for enrollment management at Purdue.