On June 21, 2022 Ultima Genomics, Inc. and Exact Sciences Corporation (Nasdaq: EXAS) reported that they have entered a long-term supply agreement for Ultima’s next-generation sequencing (NGS) technologies (Press release, Exact Sciences, JUN 21, 2022, View Source [SID1234616123]). Under the terms of the supply agreement, Ultima Genomics will provide access to its NGS products, which are based on a new architecture designed to enable sequencing at a fraction of the cost of other commercially available technologies . The companies also plan to develop one or more of Exact Sciences’ advanced cancer diagnostic tests using Ultima’s sequencing technology. In conjunction with the agreement, Exact Sciences became an investor in Ultima and joined its ongoing early access program for its high-throughput NGS instrument platform, the UG 100. The collaboration is aimed at driving down the high cost of sequencing to improve patient access to genomics-based testing and human health.

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"Exact Sciences believes access to differentiated and affordable genomics technologies is critical to providing patients better information before diagnosis and across all stages of cancer treatment," said Kevin Conroy, chairman and CEO of Exact Sciences. "Ultima’s mission to drive down the cost of sequencing and increase the use of genomic information supports our goal to provide accurate and affordable testing options across the cancer continuum. This is particularly important for applications like cancer screening, minimal residual disease, and recurrence monitoring, which could lead to millions of tests per year."

"We founded Ultima Genomics with the mission to continuously drive the scale of genomic information. We believe our mission is closely aligned with the goals of our customers, and we look forward to enabling Exact Sciences and others to perform sequencing at a fraction of the cost today," said Gilad Almogy, CEO of Ultima Genomics. "We designed our new sequencing architecture to scale beyond conventional technologies, and are excited to soon make the UG 100, our first instrument using this architecture, commercially available to more customers. In the future, we aim to continuously improve our technology, further drive down costs, and increase the scale of genomic information to improve patient outcomes."

Over the last 5 years, Ultima Genomics has developed a fundamentally new sequencing architecture designed to scale beyond conventional approaches, including completely different flow cell engineering and sequencing chemistry, and machine learning. Ultima is currently in an early access program for the UG 100, its first high-throughput NGS instrument using this new technology architecture.

On June 21, 2022 Kintara Therapeutics, Inc. (Nasdaq: KTRA) ("Kintara" or the "Company"), a biopharmaceutical company focused on the development of new solid tumor cancer therapies, reported that President and CEO Robert E. Hoffman will present a corporate overview at the Alliance Global Partners Summer Healthcare Conference (Press release, Kintara Therapeutics, JUN 21, 2022, View Source [SID1234616122]). The conference is being held virtually on June 21 – 22, 2022.

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Mr. Hoffman will be available for one-on-one meetings. For more information, please contact your registered AGP representative or [email protected].

On June 21, 2022 Phynova Group Ltd and Ingredients Plus reported a distribution partnership for Reducose, for use in Supplement applications to customers in Oceania (Press release, Phynova, JUN 21, 2022, View Source [SID1234616120]). Reducose is Phynova’s patented and clinically researched White Mulberry leaf extract that supports significant lowering of post-meal blood sugar and insulin response as well as enabling food and beverage applications to become Low GI.

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Stephane Ducroux, CEO at Phynova, said: "We are delighted to have a distribution partnership with Ingredients Plus. Phynova’s strategy is to partner with market focused experts such as Ingredients Plus, who have a proven track record of building deep customer relationships and using ingredients with a strong science like Reducose.

Peter Schwarczer, Business Manager at Ingredients Plus said: "We are excited to partner with Phynova by bringing a unique ingredient into the ANZ market and we look forward to a long-term and fruitful cooperation."

On June 21, 2022 Labcorp (NYSE: LH), a leading global life sciences company, reported a new collaboration with HealthVerity, Inc., the leader in Identity, Privacy, Governance, and Exchange (IPGE) for real-world data (RWD), that will expand Labcorp’s comprehensive, end-to-end drug development and clinical trial programs (Press release, LabCorp, JUN 21, 2022, View Source [SID1234616118]).

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HealthVerity’s IPGE platform, an integrated technology and RWD infrastructure, enables Labcorp Drug Development and other participating companies to access fully interoperable, HIPAA-compliant data from the U.S.’s largest ecosystem1 of health care and consumer data.

"This collaboration allows Labcorp to expand existing end-to-end solutions for drug and diagnostics development, commercialization and clinical trial efforts to include large-scale access to real-world data for research applications," said Dr. Paul Kirchgraber, CEO of Labcorp Drug Development. "By applying advanced analytics, Labcorp can help its clients improve their processes and reach better outcomes. Our substantial repository of test results can also help study sponsors more quickly and accurately assess patient eligibility for clinical trials, enroll patients faster and accelerate the availability of new medicines."

Now more than ever, study sponsors are seeing the potential of RWD to yield longitudinal patient insights before, during and after trials. With more predictive analytics and artificial intelligence applications requiring comprehensive and fully interoperable RWD, Labcorp can align de-identified patient data with ten times greater accuracy2 than industry alternatives by using the HealthVerity IPGE platform. In addition, access to HealthVerity’s RWD with on-demand de-identification and data linkage capabilities reinforces Labcorp’s ability to be a trusted source of information for its clients.

"Fragmentation of patient data is at an all-time high, and the goal is no longer just connecting this data," said Andrew Kress, CEO of HealthVerity. "Rather, the goal is making data more accessible and useful for gaining a detailed understanding of patient journeys. With analytics and applications requiring more frictionless access to the data itself, the HealthVerity IPGE platform stands alone in offering the ability to combine transaction-level patient data in a de-identified, fully interoperable manner, and delivering it directly into the client’s applications of choice."

Labcorp is an investor in HealthVerity through the Labcorp Venture Fund.

On June 21, 2022 Iktos, a company specialized in Artificial Intelligence for new drug design, reported a research collaboration with Zealand Pharma A/S (Nasdaq: ZEAL) (CVR-no. 20045078), a biotechnology company changing lives with innovative peptide-based medicines to co-develop generative and predictive AI technologies for peptide drug design (Press release, Iktos, JUN 21, 2022, View Source [SID1234616117]).

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Iktos’ AI technology, based on a comprehensive data-driven chemical structure generation technology, brings new insights into the drug discovery process. This technology automatically designs virtual novel molecules with all the characteristics of a successful drug molecule. Iktos has recently diversified its R&D efforts into the development of an AI technology for peptide-based therapeutics and has developed state-of-the-art generative and predictive models to facilitate design of novel peptide therapeutics with desired properties.

Zealand Pharma A/S has a track record of successfully inventing and developing novel peptide-based drugs. This success is based on the extensive experience in improving the therapeutic characteristics of peptides. Zealand Pharma has a keen interest in expanding its computational chemistry toolbox to include AI and machine learning based approaches for the design of novel therapeutic peptides (View Source).

Under the agreement, Zealand will contribute its expertise in peptide drug discovery to Iktos’ generative modelling technologies and expertise in machine learning and AI.

"We are very pleased to join forces with Zealand Pharma and leverage their deep know-how in peptide therapeutics with our state-of-the-art existing technology assets to peptide drug discovery" commented Yann Gaston-Mathé, President and CEO of Iktos. "We look forward to working with Zealand’s experienced R&D team to build leading/state of the art peptide generative and predictive modelling technology in the field of peptides – a new area for Iktos."