MARKER THERAPEUTICS TO HOST CLINICAL PROGRAM UPDATE CONFERENCE CALL AND WEBCAST ON WEDNESDAY, FEBRUARY 16, 2022

On February 8, 2022 Marker Therapeutics, Inc. (Nasdaq:MRKR), a clinical-stage immuno-oncology company specializing in the development of next-generation T cell-based immunotherapies for the treatment of hematological malignancies and solid tumor indications, reported that it will host a conference call and webcast on Wednesday, February 16, 2022 at 5:00 p.m. EST to provide an update on the Company’s clinical programs, manufacturing processes and pipeline (Press release, Marker Therapeutics, FEB 8, 2022, View Source [SID1234607910]).

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The webcast will be accessible in the Investors section of the Company’s website at WWW.MARKERTHERAPEUTICS.COM. Individuals can participate in the conference call by dialing 877-869-3847 (domestic) or 201-689-8261 (international) and referring to the "Marker Therapeutics Clinical Program Update Call."

The archived webcast will be available for replay on the Marker website following the event.

Arcellx Announces Closing of Initial Public Offering and Exercise in Full of the Underwriters’ Option to Purchase Additional Shares

On February 8, 2022 Arcellx, Inc. (NASDAQ: ACLX), a biotechnology company reimagining cell therapy through the development of innovative immunotherapies for patients with cancer and other incurable diseases, reported the closing of its initial public offering of 9,487,500 shares of its common stock, which includes the exercise in full of the underwriters’ option to purchase 1,237,500 additional shares of its common stock, at a public offering price of $15.00 per share (Press release, Arcellx, FEB 8, 2022, View Source [SID1234607896]). The aggregate gross proceeds from the offering were $142.3 million, before deducting underwriting discounts and commissions and other offering expenses payable by Arcellx. All of the shares of common stock were offered by Arcellx. Arcellx’s common stock began trading on the Nasdaq Global Select Market on February 4, 2022, under the ticker symbol "ACLX."

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BofA Securities, SVB Leerink, Barclays and William Blair acted as joint book-running managers for the offering.

A registration statement relating to the offering has been filed with the Securities and Exchange Commission and became effective on February 3, 2022. The offering was made only by means of a prospectus, copies of which may be obtained from: BofA Securities, NC1-004-03-43, 200 North College Street, 3rd Floor, Charlotte, NC 28255-0001, Attention: Prospectus Department, or by email at [email protected]; SVB Securities LLC, Attention: Syndicate Department, 53 State Street, 40th Floor, Boston, Massachusetts 02109, by telephone at 1-800-808-7525, ext. 6105, or by email at [email protected]; Barclays Capital Inc., c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, New York 11717 or by email at [email protected] or by telephone at (888) 603-5847; or William Blair & Company, L.L.C., Attention: Prospectus Department, 150 North Riverside Plaza, Chicago, IL 60606, by telephone at 1-800-621-0687, or by email at [email protected]. Copies of the final prospectus related to the offering are available at www.sec.gov.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.

INmune Bio, Inc. to Present at the BIO CEO & Investor Conference

On February 8, 2022 (GLOBE NEWSWIRE) — INmune Bio, Inc. (NASDAQ: INMB) (the "Company"), a clinical-stage immunology company focused on developing treatments that harness the patient’s innate immune system to fight disease, reported that Raymond J. Tesi, MD, President and CEO, will present at the BIO CEO & Investor Conference being held February 14 – 17 at the Marriott Marquis in New York City (Press release, INmune Bio, FEB 8, 2022, View Source [SID1234607895]).

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BIO CEO & Investor Conference
Presentation Date: Tuesday, February 15, 2022
Presentation Time: 9:15 AM Eastern Time

Please contact your representative at BIO to schedule a virtual one-on-one meeting with INmune Bio during the respective conference.

Synlogic To Present at Upcoming Investor and Industry Conferences

On February 8, 2022 Synlogic, Inc. (Nasdaq: SYBX), a clinical-stage biotechnology company developing medicines for metabolic and immunological diseases through its proprietary approach to synthetic biology, reported that members of the executive team will present at the following investor and industry conferences (Press release, Synlogic, FEB 8, 2022, View Source [SID1234607879]):

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BIO CEO & Investor Conference: Molly Harper, Chief Business Officer, will present at 10:00 am EST on Monday, February 14, 2022.
11th Annual SVB Leerink Global Healthcare Conference: Aoife Brennan, M.B. Ch.B., President and Chief Executive Officer, will participate in a Fireside Chat at 12:00 pm EST on Thursday, February 17, 2022.
A live webcast of the presentations, if available, can be accessed under "Event Calendar" in the Investors & Media section of the Company’s website. Archived versions of webcasts will be available on the Synlogic website.

Sonnet BioTherapeutics Provides Fiscal Year 2022 First Quarter Business and Earnings Update

On February 8, 2022 Sonnet BioTherapeutics Holdings, Inc. (NASDAQ:SONN) ("Sonnet" or the "Company"), a biopharmaceutical company developing innovative targeted biologic drugs, reported its financial results for the three months ended December 31, 2021 and provided a business update (Press release, Sonnet BioTherapeutics, FEB 8, 2022, View Source [SID1234607878]).

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"Throughout the quarter, we’ve continued to advance towards the clinic with our proprietary Fully Human Albumin Binding (FHAB) pipeline assets, and our partnered product, SON-080," said Pankaj Mohan, Ph.D., Founder and CEO. "We continue to generate additional clinical product stability data for SON-1010 (IL12-FHAB) for the FDA and we have initiated cGMP manufacturing for SON-080 (Low-dose IL-6), with both assets on track to initiate clinical studies in the second quarter of this year. Additionally, we have completed R&D manufacturing for a non-human primate non-GLP toxicology study for SON-1210 (IL12-FHAB-IL15), with the study initiation planned for the first half of 2022 and have made important progress with our SON-1410 (IL18-FHAB-IL12) and SON-3015 (Anti-IL6-FHAB-Anti-TGFβ) bispecific assets."

"We remain pleased with our ongoing financing strategy and continue to provide the company with the funding necessary to advance our R&D activities into the clinic and grow the company in 2022," commented Jay Cross, CFO.

FY 2022 First Quarter and Recent Corporate Updates

Sonnet provided the following corporate updates for the 2022 calendar year:

●Generating additional clinical product stability data for SON-1010 for the FDA in 1Q22; SON-1010 is on track for clinical study initiation in 2Q22.
●Completed preparations for cGMP manufacturing of SON-080, initiated manufacturing in January, and on track for clinical study initiation in 2Q22.
●Completed R&D manufacturing for SON-1210 with initiation of a non-GLP pre-clinical toxicity study in non-human primates on track for 1H22.
●Completed sequence confirmation for SON-3015 and preparing for initial in vivo mice studies in 2H22.
●Lead optimization is underway to initiate CMC with cell line development for SON-1410 in 2Q22.

FY 2022 First Quarter Ended December 31, 2021 Financial Results

●As of December 31, 2021, Sonnet had $19.4 million cash on hand.
●Research and development expenses were $4.3 million for the three months ended December 31, 2021, compared to $3.9 million for the three months ended December 31, 2020. The increase of $0.4 million was primarily due to the development of the cell lines for SON-1010, SON-1210 and SON-080, and an increase in payroll and share-based compensation expense as we continue to expand our operations.
●General and administrative expenses were $2.1 million for the three months ended December 31, 2021, compared to $2.0 million for the three months ended December 31, 2020. The increase of $0.1 million relates to an increase in consulting fees.