On January 20, 2022 Geron Corporation (Nasdaq: GERN) reported that it has granted non-statutory stock options to purchase an aggregate of 435,800 shares of Geron common stock as inducements to newly hired employees in connection with commencement of employment with the Company (Press release, Geron, JAN 20, 2022, View Source [SID1234605624]).

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The stock options were granted on January 19, 2022 at an exercise price of $1.10 per share, which is equal to the closing price of Geron common stock on the date of grant. The stock options have a 10-year term and vest over four years, with 12.5% of the shares underlying the options vesting on the six-month anniversary of commencement of employment for the respective employees and the remaining shares vesting over the following 42 months in equal installments of whole shares, subject to continued employment with Geron through the applicable vesting dates. The options were granted as material inducement to employment in accordance with Nasdaq Listing Rule 5635(c)(4) and are subject to the terms and conditions of the stock option agreements covering the grants and Geron’s 2018 Inducement Award Plan, which was adopted December 14, 2018 and provides for the granting of stock options to new employees.

On January 20, 2022 Eli Lilly and Company (NYSE: LLY) will report its fourth-quarter and full-year 2021 financial results on Thursday, Feb. 3, 2022 (Press release, Eli Lilly, JAN 20, 2022, View Source [SID1234605623]). Lilly will also conduct a conference call on that day with the investment community and media to further detail the company’s financial performance.

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The conference call will begin at 9 a.m. Eastern time. Investors, media and the general public can access a live webcast of the conference call through a link that will be posted on Lilly’s website at View Source A replay will also be available on the website following the conference call.

On January 20, 2022 Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer, reported that James Dentzer, President and Chief Executive Officer, will participate in the following upcoming conferences (Press release, Curis, JAN 20, 2022, View Source [SID1234605620]):

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B. Riley Virtual Oncology Conference, Thursday, January 27, 2022 at 1:30 p.m. ET

SVB Leerink 11th Annual Global Healthcare Conference, Friday, February 18, 2022 at 11:20 a.m. ET

Live webcasts of the presentations will be available under "Events & Presentations" in the Investors section of the Company’s website at www.curis.com. Archived replays of the webcasts will be available on the Curis website for 90 days following the event.

On January 20, 2022 Mabwell (Shanghai) Bioscience reported a $547 million IPO on Shanghai’s STAR Board (Press release, Mabwell Biotech, JAN 20, 2022, View Source [SID1234605619]). Established in 2017, Mabwell is a clinical-stage antibody developer with 15 assets in its pipeline: three are in BLA stage, three in pivotal trials and six in Phase I/II trials. The company’s lead candidates are biosimilars. It develops therapies for indications in auto-immune diseases, oncology, metabolic disorders, ophthalmologic diseases and infectious diseases. The company has a wholly-owned US subsidiary, Mabwell Therapeutics, in San Diego. Mabwell’s shares have fallen 22% below their IPO price.

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On January 20, 2022 Champions Oncology, Inc. (Nasdaq: CSBR), a leading global technology-enabled biotech that is transforming drug discovery through innovative AI-driven pharmaco-pheno-multiomic integration, reported a therapeutic co-development partnership with Fannin Innovation Studio (Press release, Champions Oncology, JAN 20, 2022, View Source [SID1234605618]). The partnership will combine novel therapeutic targets identified within Champions’ Lumin platform with Fannin’s Therapeutic Raptamer platform to develop next generation Raptamer Drug Conjugates (RDC’s). RDCs engage tumor-specific therapeutic targets at a cell’s surface to deliver potent toxic payloads to the tumor, without affecting normal cells. The planned partnership will initiate with a single program focused on a previously unexplored target present in tumor indications such as non-small cell lung cancer (NSCLC), head and neck cancer, and other solid tumors. The partnership will also leverage the unique experimental platforms available at Champions to ensure rapid and efficient development towards clinical evaluation. Under the terms of this agreement, Champions and Fannin will share equal ownership of the developed therapeutic and establish a joint venture after specific development milestones are met.

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Ronnie Morris, MD, President and CEO of Champions Oncology, said "We’re excited to announce another partnership in drug discovery and development. Our experimental and digital research platforms continue to expand our understanding of tumor cell biology. With our AI-driven analytics, and deeply characterized dataset, we can completely reconstruct a tumor at the molecular level and identify differences between a tumor cell and normal cell. Over the past year, we have identified a considerable number of therapeutic targets that were previously overlooked using conventional methods, and we continue to scale our efforts to reveal others. The specific target being leveraged in this partnership has a profile that makes it uniquely interesting for an RDC-based therapeutic. Fannin’s Raptamer Platform is a compelling approach to therapeutic discovery, and we believe this partnership is the right approach for this target. We are eager to see this program develop with our combined expertise."

Atul Varadhachary, MD, PhD, Managing Partner of Fannin Innovation Studio, noted that "Our validated Raptamer platform provides a unique opportunity to rapidly develop selective, high-affinity ligands for targeted payload delivery to a variety of tissues, including tumors. The Raptamer platform provides complementary capabilities to Champions’ multiomic computational platform, and we are excited about our joint venture with Champions as well as the initial neo-antigenic target for our partnership."