On November 22, 2023 Veracyte, Inc. (Nasdaq: VCYT) reported that seven posters will be presented at the 24th Annual Meeting of the Society of Urologic Oncology (SUO 2023), where they will demonstrate the clinical performance of Veracyte’s Decipher Prostate Genomic Classifier in identifying patients whose prostate cancer is likely to progress and require treatment (Press release, Veracyte, NOV 22, 2023, View Source [SID1234637936]). Collectively, the posters will report data from more than 60,000 patients. The meeting will take place in Washington, DC, from November 28 to December 1.
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The American Cancer Society estimates that there will be nearly 290,000 new cases of prostate cancer in the U.S. this year. An ongoing challenge in the management of prostate cancer is distinguishing between patients whose tumors require careful monitoring, known as active surveillance, and those who require intervention. Routinely used clinical factors, such as Gleason score and prostate-specific antigen (PSA) level, are not sufficient to determine which prostate cancers are likely to progress and which are not.
"These presentations by users of the Decipher Prostate Genomic Classifier will add to the growing body of clinical evidence supporting the use of the test to help physicians guide care for their patients with prostate cancer," said Elai Davicioni, Ph.D., Veracyte’s medical director for Urology. "This breadth of real-world data truly distinguishes our genomic classifier from other molecular tests available today and serves as a strong foundation for using Decipher results to provide a more complete understanding of each patient’s cancer for more personalized care."
The following posters will be presented at the SUO 2023 meeting on Friday, December 1:
Title: Assessing molecular heterogeneity of prostate cancer biopsy sampling: Insights from the MAST trial
Presenter: Tarek Ajami, M.D., University of Miami
Poster: #214
Time: 10 a.m. to 11 a.m. ET
Title: Decipher Genomic Classifier on initial prostate biopsy is associated with Gleason score upgrading on final radical prostatectomy pathology
Presenter: John Sheng, M.D., Washington University School of Medicine in St. Louis
Poster: #226
Time: 12:45 p.m. to 1:45 p.m. ET
Title: Decipher Genomic Classifier score on initial biopsy is associated with progression from active surveillance to treatment in prostate cancer
Presenter: John Sheng, M.D., Washington University School of Medicine in St. Louis
Poster: #237
Time: 1:45 p.m. to 2:45 p.m. ET
Title: Does genomic risk score at biopsy correlate with focality of disease at radical prostatectomy: Implications for focal therapy candidates
Presenter: Jenna Winebaum, M.D., University of California, San Francisco
Poster: #189
Time: 9 a.m. to 10 a.m. ET
Title: Grade and volume progression and its association with the Decipher Genomic Classifier using patients enrolled in a prospective active surveillance protocol
Presenter: Archan Khandekar, M.D., University of Miami
Poster: #219
Time: 12:45 p.m. to 1:45 p.m. ET
Title: Molecular correlates with PSMA expression in primary prostate cancer
Presenter: Adam B. Weiner, M.D., University of California, Los Angeles
Poster: #201
Time: 10 a.m. to 11 a.m. ET
Title: Understanding population-wide genomic risk distribution and integrating clinical-genomic risk for prognostication in patients with clinically localized prostate cancer
Presenter: Udit Singhal, M.D., University of Michigan
Poster: #200
Time: 9 a.m. to 10 a.m. ET