On May 21, 2024 Medigene AG (Medigene or the "Company", FSE: MDG1, Prime Standard), an immuno-oncology platform company focusing on the discovery and development of differentiated T cell immunotherapies for solid tumors and BioNTech SE (Nasdaq: BNTX, "BioNTech") reported that their collaboration to advance T cell receptor (TCR) immunotherapies against cancer will extend beyond the initial three-year term outlined at the signing of the agreement in February 2022 (Press release, MediGene, MAY 21, 2024, https://www.pressetext.com/news/20240521012 [SID1234643505]). This extension will enable ongoing and future work required to potentially generate novel TCRs directed against multiple newly nominated antigen targets that could further expand the BioNTech warehouse of TCR candidates.

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"We are pleased about the extension of our partnership with BioNTech aiming at the development of highly differentiated TCR-based therapies for patients suffering from solid tumors. The collaboration solidifies our position as a leader in the field of TCR generation while we continue to deliver very promising TCR candidates," said Dr. Selwyn Ho, Chief Executive Officer at Medigene. "The ongoing work between our scientific teams reflects the strength of our partnership in the fight against cancer, and we look forward to making further progress in making a difference in the lives of cancer patients."

In February 2022, Medigene and BioNTech entered into a global multi-target collaboration to discover and develop T cell receptor immunotherapies against multiple cancer targets including PRAME (PReferentially expressed Antigen in MElanoma). The agreement also included non-exclusive licenses to some of the proprietary technologies contained in Medigene’s End-to-End Platform including its PD1-41BB costimulatory switch protein.

On May 21, 2024 NuCana plc (Nasdaq: NCNA) reported that Hugh Griffith, Chief Executive Officer, and Don Munoz, Chief Financial Officer, will present at TD Cowen’s 5th Annual Oncology Innovation Summit: Insights for ASCO (Free ASCO Whitepaper) & EHA (Free EHA Whitepaper) (Press release, Nucana BioPharmaceuticals, MAY 21, 2024, View Source [SID1234643500]).

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Event: TD Cowen’s 5th Annual Oncology Innovation Summit
Date: Tuesday, May 28, 2024
Time: 8:30 AM EDT
Location: Virtual

The presentation will be webcast live and available for replay under "Events & Presentations" in the Investors section of the Company’s website at www.nucana.com.

On May 21, 2024 Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, reported the appointment of Dr. Hanneke Schuitemaker, Ph.D. as Chief Scientific Officer (CSO) and Executive Committee member, effective June 3, 2024 (Press release, Valneva, MAY 21, 2024, View Source [SID1234643499]).

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Valneva decided to complement its Executive Team with an accomplished R&D leader to oversee the further evolution of the Company´s R&D portfolio. Specifically, Dr. Schuitemaker will focus on accelerating Valneva’s pre-clinical and translational R&D activities in support of the Company’s strategic ambition to provide first-, best- or only-in-class vaccine solutions.

Dr. Schuitemaker brings more than two decades of experience in vaccine discovery and development. She formerly served as Global Head of Viral Vaccine Discovery and Translational Medicine at Johnson & Johnson (J&J), with responsibility for the strategy and execution of vaccine programs on COVID-19, HIV, RSV, Ebola, and multiple other viral disease targets for almost 14 years. Prior to J&J, she worked at Sanquin, The Netherlands’ Blood Supply Foundation, and at Amsterdam University Medical Center, where she conducted research on the pathogenesis of HIV. She has a unique and solid scientific background, which is notably reflected in more than 350 scientific publications.

Thomas Lingelbach, Chief Executive Officer of Valneva, said, "Hanneke’s addition to our team represents an important step in further strengthening Valneva’s strategic leadership, especially as we continue to build our R&D portfolio beyond our advanced clinical programs against Lyme disease and the chikungunya virus. Innovation is a foundation of Valneva’s culture and strategy, and we are confident that her expertise and vision will be key in this regard."

Dr. Schuitemaker, newly appointed Chief Scientific Officer of Valneva, added, "I am extremely excited to join the fantastic team at Valneva to help strengthen the pipeline and contribute to the design and development of novel vaccines against infectious diseases. Valneva has already accomplished a great deal, having brought three vaccines from early R&D to approval1, including the world’s first licensed chikungunya vaccine2, and I can’t wait to join the organization."

On May 21, 2024 Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, reported that management will participate in the following upcoming investor conferences (Press release, Tempest Therapeutics, MAY 21, 2024, View Source [SID1234643498]):

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TD Cowen’s 5th Annual Oncology Innovation Summit – Fireside chat on Wednesday, May 29, 2024 at 2:00 p.m. ET

Jefferies Global Healthcare Conference – Presentation on Wednesday, June 5, 2024 at 4:00 p.m. ET
To access the live or archived recording of the discussions, please visit the investor section of the Tempest website at View Source

On May 21, 2024 Sanofi, Formation Bio and OpenAI reported that they are collaborating to build AI-powered software to accelerate drug development and bring new medicines to patients more efficiently (Press release, Sanofi, MAY 21, 2024, View Source [SID1234643497]). The three teams will bring together data, software and tuned models to develop custom, purpose-built solutions across the drug development lifecycle. This represents a first collaboration of its kind within the pharma and life sciences industries.

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Sanofi will leverage this partnership to provide access to proprietary data to develop AI models as it continues on its path to becoming the first biopharma company powered by AI at scale.

Paul Hudson
CEO, Sanofi
"This unique collaboration is the next significant step in our journey to becoming a pharmaceutical company substantially powered by AI. Next generation, first-of-its kind AI model customizations will be an important foundation in our efforts to shape the future of drug development for pharma and for the many patients waiting for innovative treatments."

OpenAI, the world leader in AI technology, will contribute access to cutting-edge AI capabilities, including the ability to fine-tune models, deep AI expertise and dedicated thought partnership and resources.

Brad Lightcap
COO, OpenAI
"There is massive potential for AI to accelerate drug development. We are excited to collaborate with Sanofi and Formation Bio to help patients and their families by bringing new medicines to market."

Formation Bio, an AI and tech-driven drug developer with its own pipeline of drug assets, will provide extensive engineering resources, experience operating at the intersection of pharma and AI, and its tech-driven development platform to design, develop and deploy AI technologies across all aspects of the pharma lifecycle.

Benjamine Liu
Co-Founder & CEO, Formation Bio
"I firmly believe that by combining our strengths, Sanofi, OpenAI and Formation Bio can reimagine drug development in the pharma industry. By creating and implementing customized AI agents and models designed for our industry, companies like Sanofi and Formation Bio can begin to scale with unprecedented productivity and transform the pace at which we bring new medicines to patients."

The potential positive impact of AI for patients waiting for new treatments is tremendous and Sanofi, Formation Bio and OpenAI plan to lead the way for drug developers.