On August 27, 2025 Alpha Tau Medical Ltd. ("Alpha Tau", or the "Company") (NASDAQ: DRTS, DRTSW), the developer of the innovative alpha-radiation cancer therapy Alpha DaRT, reported that CFO Raphi Levy will present and meet investors in the following five investor conferences in September 2025 (Press release, Alpha Tau Medical, AUG 27, 2025, View Source [SID1234655506]).

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The Alpha DaRT platform is a novel approach using localized alpha particle radiotherapy with the goal of destroying solid tumors while sparing surrounding healthy tissue. With broad potential applicability for local tumor control, together with signs of compelling immuno-stimulatory activity, the platform technology is being explored for utilization alone or synergistically with other cancer treatment modalities. Key milestones and pivotal data from multiple clinical trials in different indications are expected in 2025 and 2026.

Event: Citi 2025 Biopharma Back to School Summit
Format: 1×1 Meetings
Date: September 2-3, 2025
Location: Boston, MA

Event: H.C. Wainwright 27th Annual Global Investment Conference
Format: Company Presentation and 1×1 Meetings
Date: September 9, 2025
Time 3:00 – 3:30pm
Location: New York, NY

Event: Oppenheimer’s Third Annual Targeted Radiopharmaceutical Therapies in Oncology Summit
Format: 1×1 Meetings
Date: September 11, 2025
Location: New York, NY

Event: RTH & Co / Redburn Atlantic – Radiopharma Landscape Conference
Format: 1×1 Meetings
Date: September 26, 2025
Location: New York, NY

Event: Lytham Partners Fall 2025 Investor Conference
Format: 1×1 Meetings
Date: September 30, 2025
Location: Virtual

Mr. Levy will be available for 1×1 investor meetings at all conferences. Please reach out to your representatives at the respective conference organizers to schedule.

About Alpha DaRT

Alpha DaRT (Diffusing Alpha-emitters Radiation Therapy) is designed to enable highly potent and conformal alpha-irradiation of solid tumors by intratumoral delivery of radium-224 impregnated sources. When the radium decays, its short-lived daughters are released from the sources and disperse while emitting high-energy alpha particles with the goal of destroying the tumor. Since the alpha-emitting atoms diffuse only a short distance, Alpha DaRT aims to mainly affect the tumor, and to spare the healthy tissue around it.

On August 27, 2025 Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T) products for cancer and autoimmune disease, reported that it will participate in one upcoming investor conference in September (Press release, Allogene, AUG 27, 2025, View Source [SID1234655505]).

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Citi’s 2025 Biopharma Back to School Summit
Wednesday, September 3
7:30AM PT/10:30AM ET

Any available webcasts will be posted to the Company’s website at www.allogene.com under the Investors tab in the News and Events section. Following a live webcast, a replay will be available on the Company’s website for approximately 30 days.

On August 27, 2025 Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a clinical-stage biopharmaceutical company focused on developing novel product candidates for immuno-inflammatory diseases, reported that the Company will participate in two upcoming healthcare conferences in September (Press release, Aclaris Therapeutics, AUG 27, 2025, View Source [SID1234655504]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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On Wednesday September 3, 2025, at 1:00 PM EDT, Aclaris’ Chief Executive Officer Dr. Neal Walker and other members of Aclaris’ senior leadership team will participate in a fireside chat during the Cantor Global Healthcare Conference in New York, NY.

On Tuesday September 9, 2025, at 9:00 AM EDT, Dr. Walker will provide a corporate presentation during the H.C. Wainwright 27th Annual Global Investment Conference in New York, NY.
Live and archived webcasts of both events will be accessible on the Events page of View Source The webcasts will be available on the Aclaris website for at least 30 days.

On August 27, 2025 Azitra, Inc. ("Azitra") (NYSE American: AZTR), a clinical stage biopharmaceutical company focused on developing innovative therapies for precision dermatology, reported the dosing of the first patient in its Phase 1/2 clinical trial of ATR04-484, a topically applied live biotherapeutic product candidate designed to treat EGFR inhibitor ("EGFRi")-associated rash (Press release, Azitra, AUG 27, 2025, View Source [SID1234655502]). Azitra has received Fast Track designation from the FDA for EGFRi associated rash, which impacts approximately 150,000 people in the U.S. annually.

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"Dosing the first patient is an important milestone in the advancement of ATR04-484 as a potential treatment for EGFRi associated rash and in the development of our broader ATR-04 technology program," said Francisco Salva, CEO of Azitra. "Given the importance of EGFRi treatments across multiple cancers, there is a critical medical need to reduce the impact of the unique dermatologic toxicities that often accompany EGFRi treatments, often leading to interruption or discontinuation of the treatment. This trial is a first step in ATR04-484 potentially addressing this patient need and market opportunity."

Targeted cancer therapies, like EGFRis, have produced significant treatment advances for patients diagnosed with a variety of tumor types including non-small cell lung cancer (NSCLC) and colorectal cancer, but they are also associated with unique dermatologic toxicities. These side effects can severely hamper treatment efforts, causing significant physical and psychological discomfort for patients. The papulopustular rash is often the earliest and most common dermatologic adverse event of EGFRi treatment and can occur in 50-80% of patients, often impacting quality of life severely enough to interrupt or stop cancer treatment.

The multicenter, randomized, double-blind, vehicle-controlled Phase 1/2 clinical study (NCT06830863) is designed to evaluate the safety and tolerability of topical ATR04-484 for the treatment of EGFRi-associated dermal toxicity affecting the face of adult patients. ATR04-484 or its vehicle (3:1 randomization) will be applied to the face as well as affected areas on the neck, chest, back, and areas around nailbeds. The key objectives of the study will be to assess the safety and tolerability of topical ATR04-484 and to evaluate efficacy signals including severity of disease, pruritus, and pain. The bioavailability of ATR04-484 and pharmacodynamic parameters will also be studied. This clinical study will establish the basis for continued clinical development of ATR04-484.

ATR04-484 is a live biotherapeutic product candidate including an isolated, naturally derived Staphylococcus epidermidis strain in development for EGFRI-associated skin rash. The candidate was selected based on its preclinical profile of reducing IL-36γ and S. aureus levels, both of which are elevated in patients with EGFRi-associated skin rash. The strain was then engineered to be safe by deleting an antibiotic resistance gene and engineering auxotrophy to control the growth of ATR04-484.

On August 26, 2025 BioInvent reported interim report for the period January to June 2025 (Presentation, BioInvent, AUG 26, 2025, https://www.bioinvent.com/sites/bioinvent/files/pr/20250826-b8958ea1-a830-41b4-871e-759ffd4abac0-1.pdf?ts=1756189813 [SID1234656794]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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