Abkyu and Jeevan Therapeutics Announce $200 Million VHH Discovery Collaboration

On September 2, 2025 Abkyu, Inc., a biotechnology company specializing in single-domain antibody (VHH) discovery, reported a strategic discovery partnership with Jeevan Therapeutics, a biotechnology company founded by experienced industry leaders in biologics and small molecule development (Press release, Jeevan Therapeutics, SEP 2, 2025, View Source [SID1234656393]). The collaboration, valued at up to $200 million, will leverage Abkyu’s proprietary VHH discovery platform to accelerate the development of next-generation therapeutics aimed at addressing complex disease biology.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Under the agreement, Jeevan Therapeutics will gain dedicated access to Abkyu’s discovery platform and downstream engineering expertise to develop VHH candidates against its primary drug target. In return, Abkyu will receive an upfront payment and is eligible for additional regulatory and clinical milestone payments and commercial royalties.

"We couldn’t be more excited to partner with Jeevan Therapeutics," said Travis LeGuyader, co-founder of Abkyu. "Our platform was built specifically to enable the kind of therapeutics their team is developing and is designed to significantly increase the chances of success by identifying molecules that precisely match the target product profiles (TPPs) they are pursuing. Partnering with Jeevan not only allows us to leverage our platform to help address a largely underserved patient population but also to align with a team that shares our vision for the potential of VHHs and the breadth of their therapeutic applications."

"Partnering with Abkyu represents a pivotal step forward for Jeevan as we advance our mission to deliver transformative therapies for patients with significant unmet needs," said Terrence West, CEO and Co-Founder of Jeevan Therapeutics. "Abkyu’s cutting-edge VHH discovery platform, combined with our expertise in precision biologics and drug development, positions us to accelerate the creation of next-generation therapies designed to improve long-term patient outcomes."

This partnership reflects a shared vision to accelerate the development of next-generation biologics and expand treatment options for patients with significant unmet needs. By uniting Abkyu’s powerful VHH discovery platform with Jeevan’s innovative therapeutic strategy, the collaboration seeks to deliver therapies that set new standards for efficacy and long-term patient benefit.

Kairos Pharma to Present at the H.C. Wainwright 27th Annual Global Investment Conference

On September 2, 2025 Kairos Pharma, Ltd. (NYSE American: KAPA), a clinical-stage biopharmaceutical company focused on innovative cancer therapeutics, reported that John Yu, MD, CEO and Chairman, will present a corporate overview at the H.C. Wainwright 27th Annual Global Investment Conference (Press release, Kairos Pharma, SEP 2, 2025, View Source [SID1234655684]). The conference is being held on September 8 – 10, 2025 at the Lotte New York Palace Hotel.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Presentation Date:

September 5, 2025

Time:

Available on-demand starting at 7:00 AM Eastern Time

Webcast Link:

View Source

A webcast of the presentation can be accessed on the investor relations section of the Kairos Pharma website. A replay of the webcast will be archived and available following the event for 90 days.

View Source

Dr. Yu will be available for one-on-one meetings throughout the conference. To request a meeting and to register for the conference, click below:

View Source

Adicet Bio to Present at the H.C. Wainwright 27th Annual Global Investment Conference

On September 2, 2025 Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer, reported that Chen Schor, President and Chief Executive Officer, will present at the H.C. Wainwright 27th Annual Global Investment Conference being held from September 8-10, 2025 in New York (Press release, Adicet Bio, SEP 2, 2025, View Source [SID1234655682]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Details of the event are as follows:
Date: Monday, September 8, 2025
Time: 4:30 p.m. ET

The live audio webcast can be accessed on the Investors section of Adicet Bio’s website at View Source An archived replay will be available for 30 days following the presentation.

Agilent’s MMR IHC Panel pharmDx (Dako Omnis) Receives European IVDR Certification as a Companion Diagnostic Test for Colorectal Cancer

On September 2, 2025 Agilent Technologies Inc. (NYSE: A) reported that its MMR IHC Panel pharmDx (Dako Omnis) has received class C companion diagnostic (CDx) certification under EU in vitro diagnostic regulation (IVDR)1 as a CDx test for colorectal cancer (Press release, Agilent, SEP 2, 2025, View Source [SID1234655681]). MMR IHC Panel pharmDx (Dako Omnis) is indicated as an aid to identify mismatch repair (MMR) deficient CRC patients eligible for treatment with OPDIVO (nivolumab) in combination with YERVOY (ipilimumab). MMR IHC Panel pharmDx (Dako Omnis) is approved for exclusive use with the Agilent Dako Omnis automated staining solution.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The MMR pathway corrects DNA replication errors to maintain genomic stability2. Dysfunction in key MMR proteins (MLH1, PMS2, MSH2, and MSH6) causes MMR deficiency (dMMR), leading to elevated mutations, tumorigenesis, and neoantigen accumulation—features that make dMMR tumors more responsive to immunotherapy due to enhanced immune recognition3.

MMR IHC Panel pharmDx (Dako Omnis) is an immunohistochemical panel specifically developed and validated to detect the loss of function of any of the four MMR proteins in formalin-fixed paraffin-embedded colorectal cancer tissue. Agilent’s panel is the only companion diagnostic IHC panel IVDR approved to diagnose colorectal cancer patients eligible for treatment with OPDIVO in combination with YERVOY.

Nina Green, vice-president and general manager of Agilent’s Clinical Diagnostics Division remarked: "The approval of MMR IHC Panel pharmDx will provide physicians in Europe with critical information to inform treatment decisions for patients with mismatch repair deficiency (dMMR). This endorsement underscores Agilent’s leadership in the development of companion diagnostics for groundbreaking therapies."

Agilent collaborated with Bristol Myers Squibb Company to develop the MMR IHC Panel pharmDx (Dako Omnis).

OPDIVO and YERVOY are registered trademarks of Bristol-Myers Squibb Company.

Puma Biotechnology to Present at the H.C. Wainwright 27th Annual Global Investment Conference

On September 2, 2025 Puma Biotechnology, Inc. (NASDAQ: PBYI), a biopharmaceutical company, reported that Alan H. Auerbach, Chairman, Chief Executive Officer, President and Founder of Puma, will provide an overview of the Company at 1:00 p.m. EDT on Monday, September 8, at the H.C. Wainwright 27th Annual Global Investment Conference (Press release, Puma Biotechnology, SEP 2, 2025, View Source [SID1234655679]). The conference will be held September 8–10, 2025 at the Lotte New York Palace Hotel in New York City.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

A live webcast of the presentation will be available on the Company’s website at View Source The presentation will be archived on the website and available for 30 days.