Circle Pharma to Present at the 44th Annual J.P. Morgan Healthcare Conference

On January 5, 2026 Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, reported that David J. Earp, J.D., Ph.D., president and chief executive officer, will present at the 44th Annual J.P. Morgan Healthcare Conference on Wednesday, January 14, 2026 at 5:00 p.m. PT.

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Dr. Earp will provide an overview of the company’s pipeline, including CID-078, a first-in-class oral macrocyclic cyclin A/B RxL inhibitor in Phase 1 clinical development for patients with advanced solid tumors, and CID-165, a first-in-class oral macrocyclic cyclin D1 RxL inhibitor, with potential applications in malignancies, including ER-positive breast cancer and lymphomas.

(Press release, Circle Pharma, JAN 5, 2026, View Source [SID1234661709])

Ascendis Pharma to Participate in the 44th Annual J.P. Morgan Healthcare Conference

On January 5, 2026 Ascendis Pharma A/S (Nasdaq: ASND) reported that company executives will participate in the 44th Annual J.P. Morgan Healthcare Conference and provide a business update on Monday, January 12, 2026, at 10:30 a.m. Eastern Time / 7:30 a.m. Pacific Time in San Francisco, California.

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A live webcast of the presentation will be available via the Investors & News section of the Ascendis Pharma website at investors.ascendispharma.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

(Press release, Ascendis Pharma, JAN 5, 2026, View Source [SID1234661708])

Alpha Tau Submits First Pre-Market Approval Module to the FDA for Alpha DaRT® for the Treatment of Recurrent Cutaneous Squamous Cell Carcinoma (cSCC)

On January 5, 2026 Alpha Tau Medical Ltd. (Nasdaq: DRTS, DRTSW) ("Alpha Tau", or the "Company"), the developer of the innovative alpha-radiation cancer therapy Alpha DaRT reported the submission of the first module of its pre-market approval (PMA) application to the U.S. Food and Drug Administration (FDA), following the FDA’s previous decision to allow the Company to use the more flexible modular approach. The Company submitted the module as part of an application for the use of Alpha DaRT in treating recurrent cutaneous squamous cell carcinoma (cSCC), the second most common form of skin cancer, for patients not indicated for surgery or standard radiation therapy, and for whom no curative systemic treatment is available. This module is focused on comprehensive documentation with respect to non-clinical studies as required under the PMA application.

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Uzi Sofer, CEO of Alpha Tau, stated, "Alpha Tau continues its fast pace of activity, charging forward in our pursuit of potential marketing authorizations across a wide range of tumors, with an eye toward future commercialization. The decision by the FDA to allow us to submit our PMA in a modular form will hopefully allow for ongoing FDA review and feedback as each module is submitted, and we look forward to this dynamic and efficient authorization review process with the FDA."

Yaniv Sagie, VP Quality and Regulatory Affairs, added, "Thank you to our outstanding team for this great accomplishment, our first PMA module submission, and for all of the other achievements working with regulators around the world. I appreciate the support of our advisors who work closely with us and hope to accomplish great things for Alpha Tau together."

Alpha Tau is currently conducting its multi-center pivotal ReSTART study exploring the use of Alpha DaRT in recurrent cSCC, one of five clinical trials currently approved in the U.S., and anticipates completing patient recruitment in Q1 2026. Alpha Tau has received Breakthrough Device Designation from the FDA in this indication as well as for recurrent glioblastoma multiforme (GBM) and recurrent squamous cell carcinoma of the oral cavity with similar criteria, and is also part of the FDA Total Product Life Cycle Advisory Program (TAP) to accelerate market access for the potential treatment of recurrent GBM.

(Press release, Alpha Tau Medical, JAN 5, 2026, View Source [SID1234661707])

Agios to Present at the 44th Annual J.P. Morgan Healthcare Conference on January 14, 2026

On January 5, 2026 Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, reported that its management team is scheduled to present at the 44th Annual J.P. Morgan Healthcare Conference on Wednesday, January 14, 2026, at 8:15 a.m. PST / 11:15 a.m. EST.

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The live webcast will be accessible on the Investors section of the company’s website (www.agios.com) under the "Events & Presentations" tab. A replay of the webcast will be archived on the company’s website for at least two weeks following the presentation.

(Press release, Agios Pharmaceuticals, JAN 5, 2026, View Source [SID1234661706])

Orum Therapeutics Appoints Chad May as Chief Scientific Officer to Drive Degrader-Antibody Conjugate Innovation and Programs

On January 5, 2026 Orum Therapeutics (Orum or the Company) (KRX: 475830), a biotechnology company pioneering the field of degrader-antibody conjugates (DACs), reported the appointment of Chad May, Ph.D., as Chief Scientific Officer (CSO). Dr. May brings more than 20 years of oncology and immunology research experience with a track record of advancing antibody drug conjugates (ADCs), T-cell engagers, and other next-generation therapeutic platforms from concept to clinical evaluation.

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"Chad has repeatedly demonstrated an ability to take bold scientific concepts and advance them into clinical candidates across multiple therapeutic modalities," said Sung Joo (SJ) Lee, Ph.D., Founder and CEO of Orum. "His leadership experience in ADCs, T-cell engagers, and structure-driven platform design aligns with Orum’s commitment to precision engineering the next generation of degrader-antibody conjugates. Chad’s expertise strengthens our position as a leader in DAC innovation and supports our progress toward meaningful clinical milestones."

As CSO, Dr. May will provide scientific vision and R&D leadership, guiding the strategic direction, discovery, and advancement of Orum’s pipeline, including the continued evolution of the Company’s proprietary DAC platforms and programs. He will oversee scientific strategy across discovery, translational research, and preclinical development and will play a central role in shaping the next stage of Orum’s technology innovation and pipeline growth.

"The opportunity to join Orum at this stage of growth is incredibly compelling," said Dr. May. "The Company’s Dual-Precision Targeted Protein Degradation approach provides a powerful foundation for creating new classes of degraders guided by antibody specificity. I am excited to work closely with the talented scientific and leadership teams to advance Orum’s DAC platforms, expand therapeutic applications across cancer and other serious diseases, and drive the next wave of innovation in degrader-antibody conjugates."

Dr. May joins Orum from Serotiny, where he served as CSO and oversaw the advancement of a novel gene and cell therapy platform through the company’s post-acquisition integration into Johnson & Johnson. Previously, he served as Senior Vice President of Research and Development at Maverick Therapeutics, where he co-founded and built the R&D organization, advanced multiple conditionally active T-cell engager programs into clinical trials, and led the company’s build-to-buy collaboration with Takeda. Earlier in his career, Dr. May held scientific leadership roles at Pfizer, where he led teams developing T-cell engagers and ADCs and advanced several programs into IND-enabling studies and clinical development. His prior work at ImClone Systems involved the design, conjugation, and evaluation of antibody-based therapeutics. Over his career, Dr. May has built and led high-performing scientific teams, contributed to numerous first-in-class program nominations, and authored more than 30 publications and patents.

(Press release, Orum Therapeutics, JAN 5, 2026, View Source [SID1234661695])