Cerenome Announces Up to $20 Million Financing Facility with Royalty-Based Repayment

On September 10, 2026 Cerenome, Inc. (Nasdaq: CNSY) ("Cerenome" or the "Company"), a CNS oncology company advancing an integrated platform of precision diagnostics, targeted therapeutics, and artificial intelligence, reported that it has entered into a financing agreement with 3i, LP ("3i Fund") for a senior secured facility of up to $20 million with royalty-based repayments. Under the agreement, the Company received initial funding at closing, with future tranches available upon achieving certain milestones.

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The financing is intended to support the scale-up of the Company’s proprietary laboratory-developed tests, particularly its CNSide cerebrospinal fluid ("CSF") assay platform.

"Cerenome is grateful for the support of the 3i Fund team, and we look forward to a long-term relationship," said Andrew Sims, Cerenome’s Chief Financial Officer. "This facility is designed to be minimally dilutive to stockholders while supporting the next stage of commercial scale-up and development of CNSide, specifically growing sales and broadening the pipeline. We forecast our cash runway is now well into 2028 when we consider, the 3i facility, other existing facilities along with current cash and forecasted CNSide related sales and cash flow."

Additional transaction details are included in a Current Report on Form 8-K to be filed by the Company with the U.S. Securities and Exchange Commission.

(Press release, Cerenome, SEP 10, 2026, View Source [SID1234670718])

Champions Oncology Reports Revenue of $15.2 Million

On September 10, 2026 Champions Oncology, Inc. (Nasdaq: CSBR), a leading translational oncology research organization, reported its financial results for its first quarter of fiscal 2027, ended July 31, 2026.

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First Quarter and Recent Highlights:

•Revenue of $15.2 million, an increase of 8.8% year over year
•Oncology services margin of 51%, compared with 43% in the prior-year period
•Adjusted EBITDA of $671,000, compared with $59,000 in the prior-year period
•Continued investment in the Company’s commercial organization, data platform and strategic growth initiatives

Robert Brainin, CEO of Champions, commented, "We delivered strong performance in the first quarter of fiscal 2027, with improved study execution and conversion in our core research services business driving higher revenue and materially better margins. We are also seeing increased commercial activity around our data offerings as we work to broaden that business across a larger customer base."

"At the same time, we continued to invest in our commercial organization, radiopharmaceutical capabilities, data platform and target discovery initiatives. Our focus remains on building sustainable growth across the business while continuing to improve profitability."

David Miller, CFO of Champions, added, "Revenue increased 8.8% in the first quarter, while oncology services margin improved to 51% from 43% in the prior-year period. Adjusted EBITDA increased to $671,000 from $59,000 in the prior-year quarter, demonstrating the operating leverage in the business as revenue grows.

"We are continuing to build on the foundation established last year, with a focus on driving revenue growth, maintaining expense discipline and converting that growth into improved profitability."

First Fiscal Quarter Financial Results

Total oncology revenue increased 8.8% to $15.2 million from $14.0 million in the prior-year period. Growth was driven primarily by higher core research services revenue, reflecting improved conversion of contracted work into revenue, together with increased data license revenue.

Total costs and operating expenses for the first quarter of fiscal 2027 were $15.6 million compared to $14.5 million in the prior-year period, an increase of $1.1 million or 7.7%.

For the first quarter of fiscal 2027, Champions reported a net loss of $426,000, compared with a net loss of $466,000 in the prior-year period. Adjusted EBITDA, which is defined as net loss excluding stock-based compensation, depreciation and amortization expenses, other income or expense, taxes and a loss on the disposal of lab equipment, increased to $671,000 from $59,000, reflecting higher revenue and improved oncology services margin while the Company continued to invest in its expanded commercial organization and growth initiatives. The current-quarter net loss included $766,000 of stock-based compensation and $314,000 of depreciation and amortization expense.

Cost of oncology revenue was $7.5 million, for the three months ended July 31, 2026, a decrease of $461,000, or 5.8%, compared to $8.0 million in the prior-year period. Oncology services margin improved to 51% from 43% in the prior-year period, reflecting higher revenue and lower third-party radiolabeling costs. Oncology services margin and profit are defined below in our Non-GAAP financial information discussion.

Research and development expense for the three months ended July 31, 2026 was $2.3 million, an increase of $262,000 or 12.6%, compared to $2.1 million for the three months ended July 31, 2025. The increase was primarily attributable to higher share-based compensation expense related to Corellia, our wholly owned subsidiary focused on target discovery. Sales and marketing expense for the quarter was $3.1 million, an increase of $1.2 million, or 66.6%, compared to $1.9 million in the prior year period. The increase reflected the Company’s previously discussed investment in expanding its commercial organization to support growth in both research services and data licensing. General and administrative expense for the three months ended July 31, 2026 was $2.7 million, an increase of $103,000, or 4.0%, compared to $2.6 million for the three months ended July 31, 2025.

Net cash used in operating activities was approximately $492,000 for the quarter, driven primarily by normal working capital movements, including a decrease in accounts payable and an increase in accounts receivable. The Company ended the quarter with approximately $4.4 million of cash and no debt.

Conference Call Information:
The Company will host a conference call today at 4:30 p.m. EDT (1:30 p.m. PDT) to discuss its first quarter financial results. To participate in the call, please call 888-506-0062 (Domestic) or 973-528-0011 (International) and enter the access code 938837, or provide the verbal reference "Champions Oncology".

(Press release, Champions Oncology, SEP 10, 2026, View Source [SID1234670717])

BioLineRx and Hemispherian AS to Present Encouraging GLIX1 Preclinical Efficacy Data and its Phase 1/2a Trial Design at the 21st Meeting of the European Association of
Neuro-Oncology (EANO 2026)

On September 10, 2026 BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage biopharmaceutical company pursuing life-changing therapies in oncology and rare diseases, and Hemispherian AS, a clinical-stage oncology company developing novel small molecule therapeutics, reported that two abstracts featuring GLIX1 have been accepted for presentation, including one selected for oral presentation highlighting the preclinical efficacy of GLIX1 in orthotopic glioblastoma models, at the 21st Meeting of the European Association of Neuro-Oncology (EANO 2026), which will be held September 24-27 in Rome, Italy.

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"We are very pleased to be presenting our pre-clinical data and clinical trial design at EANO, Europe’s premier neuro-oncology conference," stated Philip Serlin, Chief Executive Officer of BioLineRx. "Notably, our preclinical data demonstrating the potent anti-tumor effect of GLIX1 in GBM across multiple in-vivo studies, including two orthotopic cell-derived xenograft GBM models as well as a temozolomide-resistant patient derived xenograft model, will be featured in a mini-oral presentation. Together with our e-poster highlighting the design of our first-in-human Phase 1/2a clinical trial, which is actively enrolling patients, these presentations showcase the breadth and momentum of the GLIX1 program."

Abstract Details:

Title: GLIX1, a TET2 activator targeting the DNA damage response: Potent anti-tumor activity across multiple orthotopic glioblastoma models

Presenter: Dr. Adam Robertson, Ph.D., Chief Scientific Officer, Hemispherian AS

Session type: Mini Oral Session

Session number/title: MO02-Microenvironment, preclinical models and treatment resistance

Presentation Date/time: Friday, September 25, 2026, 6:00-6:30pm CEST (12:00-12:30pm EDT)

Summary: GLIX1, an oral TET2 activator targeting the DNA damage response, showed high in vitro potency across cancer cell lines and increased TET2-dependent 5hmC generation in biochemical assays, in vitro, and in vivo xenograft models. In mice, GLIX1 achieved brain exposures at 68-85% of plasma levels, supporting CNS penetration. In GBM genomic 5hmC is markedly reduced versus healthy brain tissue, reflecting impaired TET2 activity. Together, these data provide a strong rationale for GLIX1 treatment of GBM, one of the most aggressive cancers where more effective treatments are desperately needed.

(Press release, BioLineRx, SEP 10, 2026, View Source [SID1234670716])

Avenzo Therapeutics to Present Preliminary Phase 1 Study Results of AVZO-1418, a Potentially Differentiated EGFR/HER3 Bispecific Antibody-Drug Conjugate, at the 38th EORTC-NCI-AACR Symposium

On September 10, 2026 Avenzo Therapeutics, Inc. ("Avenzo"), a clinical-stage biotechnology company developing next-generation oncology therapies, reported the acceptance of an abstract for poster presentation at the 38th Symposium on Molecular Targets and Cancer Therapeutics hosted by the European Organisation for Research and Treatment of Cancer (EORTC), the National Cancer Institute (NCI), and the American Association for Cancer Research (AACR) (Free AACR Whitepaper). The EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) Symposium will take place in Barcelona, Spain from November 18-20, 2026.

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Avenzo will present preliminary safety, tolerability, and efficacy results from the ongoing Phase 1 portion of AVENTINE-1, a Phase 1/2 study evaluating AVZO-1418, its potentially differentiated EGFR/HER3 bispecific antibody-drug conjugate.

Details of the poster presentation are as follows:

Abstract: 81
Title: Preliminary phase 1 results from AVENTINE-1, a phase 1/2 study of AVZO-1418, an EGFR-HER3 bispecific antibody-drug conjugate (BsADC) for the treatment of patients with locally advanced or metastatic solid tumors
Poster #: PB-081
Poster Session: Antibody-Drug Conjugates
Date and Time: Wednesday, November 18, 2026, 12:00 to 7:00 p.m. CET
Location: Exhibition Hall

(Press release, Avenzo Therapeutics, SEP 10, 2026, View Source [SID1234670715])

Twist Bioscience to Present at Baird 2026 Global Healthcare Conference

On September 9, 2026 Twist Bioscience Corporation (NASDAQ: TWST), a mid-cap growth and value biotech company, reported that Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience, and Adam Laponis, CFO of Twist Bioscience, will participate in a fireside chat at the Baird 2026 Global Healthcare Conference on Tuesday, September 15, 2026 at 1:25 pm Eastern Time in New York City.

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The fireside chat will be webcast live and can be accessed by visiting the "Investor Calendar" page of the investor relations section of the company’s website here. A replay of the fireside chat will be archived for a period of 30 days following the conclusion of the live events.

(Press release, Twist Bioscience, SEP 9, 2026, View Source [SID1234670712])