Teiko to Present Four Posters at the SITC 2026 Annual Meeting

On November 3, 2026 Teiko, a CLIA clinical laboratory focused on monitoring the immune response, reported that the Company will present four posters at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)’s (SITC) (Free SITC Whitepaper) 41st Annual Meeting.

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Stabilized Whole Blood from Patients with Cancer

Title: Enhanced Preservation of Real-World Diseased Immune Signatures in Stabilized Whole Blood Enables Longitudinal Studies of Multiparameter Immune Monitoring
Presenting Author(s): Chaoyuan Kuang, MD, PhD, Albert Einstein College of Medicine and Angelynn Huang
Abstract Number: 44
Session Date: Saturday, November 7, 2026, 12:00 to 1:30 p.m. and 6:40 to 8:10 p.m. MST
TokuKit has shown strong stability of immune cell populations and functional subsets over weeks, months, and even years in healthy donor blood. But what about samples from patients, where immune cells can be more fragile and in very different functional states? Teiko’s latest research shows the stability holds: in TokuKit-stabilized blood from patients with NSCLC, measurements at baseline and after six months at −80°C correlated at r > 0.99 across 41 immune populations and 450+ functional subsets.

AI-Assisted Panel Design

Title: AI-Assisted Cytometry Panel Design for Cancer Immunotherapy (Promptable Panels)
Presenting Author: Landon Wellendorf
Abstract Number: 47
Session Date: Friday, November 6, 2026, 12:15 to 1:45 p.m. and 5:30 to 7:00 p.m. MST
Designing custom cytometry panels can take hours of tedious research. Researchers must manually select markers and build complex gating hierarchies for each study. To simplify this process, Teiko developed Promptable Panels, an AI-enabled design tool built to create custom panels from natural-language descriptions of study objectives. The integrated AI agent uses Teiko’s library of 150+ validated antibodies to generate fit-for-purpose panels supporting 40+ markers and 800+ immune populations, delivering interactive gating hierarchies, real-time channel counts, and cost estimates to accelerate panel development and study setup.

Antigen Density

Title: Antigen density quantification by mass cytometry using quantum simply cellular bead-based calibration
First Author: Diego López, PhD, Teiko
Presenting Author: Diego López, PhD, Teiko
Abstract Number: 46
Session Date: Saturday, November 7, 2026, 12:00 to 1:30 p.m. and 6:40 to 8:10 p.m. MST
Owing to a lack of standardized and interlab-validated methods, antigen density quantification (ADQ) has less than 0.5% penetration in clinical trials. Each run needs its own calibration, and controls are not reliably available for every time point. Without comparable and quantifiable values, targeted therapeutics including antibody-drug conjugates, bispecific T-cell engagers, and CAR-T developers cannot set antigen density-engagement thresholds for successful immune responses. Cytometry-based approaches primarily provide relative measurements of antigen expression, limiting their utility for ADQ. To address this limitation, Teiko developed a bead-based calibration workflow using Quantum Simply Cellular beads to convert mass cytometry signal into standardized estimates of antigen density (molecules per cell). This approach expands the utility of mass cytometry for quantitative target characterization, supporting therapeutic target selection, drug development, and translational research.

Phosphoprotein Profiling

Title: Point-of-Collection Whole Blood Fixation Enables Robust Phosphoprotein Profiling by Mass Cytometry for Longitudinal Clinical Trials
First Author: Lily Shang, PhD, Teiko
Presenting Author: Justin Jarrell, PhD, Teiko
Abstract Number: 45
Session Date: Friday, November 6, 2026, 12:15 to 1:45 p.m. and 5:30 to 7:00 p.m. MST
Phosphoprotein readouts are increasingly used in clinical trials, but phosphorylation states can change within minutes of collection. Teiko’s new research shows that immediate whole blood fixation with TokuKit preserves basal signals across six phosphoproteins for more than 6 weeks, avoiding the signal loss that comes with conventional PBMC processing.

All posters will also be available on the SITC (Free SITC Whitepaper) virtual meeting platform beginning November 6, 2026 at 9 a.m. ET. Attendees can also meet the Teiko team at booth #916.

(Press release, Teiko, NOV 3, 2026, View Source [SID1234674116])

Akamis Bio to Present Data from a Phase 1 Study of NG-348 in Patients with Advanced Epithelial Tumors at SITC 2026

On November 3, 2026 Akamis Bio, a clinical-stage oncology company working to advance the standard of care in colorectal cancer, reported an upcoming poster presentation of first-in-human clinical data from a Phase 1 study of NG-348 at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) Annual Meeting 2026, being held from November 4–8, in Phoenix, Arizona.

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NG-348 is an intravenously delivered oncolytic immunotherapy designed to drive intratumoral expression of two membrane-bound proteins that provide key signals for T cell activation: anti-CD3 single-chain variable fragment (scFv) and CD80. Tumor-cell surface expression of these molecules triggers antigen independent T-cell activation within the tumor microenvironment (TME), enabling direct tumor cell killing. By combining direct T cell engagement with oncolysis, NG-348 stimulates a robust anti-tumor response locally within the TME while also offering the potential to overcome immunotherapy resistance. The Phase 1 study assessed the safety, tolerability and preliminary anti-tumor effects of NG-348 monotherapy in patients with metastatic or advanced epithelial tumors refractory to standard therapies.

Poster Presentation Details:

Title: Phase 1 first-in-human study of NG-348 – an oncolytic adenovirus expressing CD80 and anti-CD3 scFv in patients with advanced epithelial tumors
Abstract: #497
Date and Time: November 6, 2026, 10 a.m. – 2 p.m. and 5 p.m. – 7 p.m. MT
Location: Phoenix Convention Center, North Exhibition Halls 4–6

(Press release, Akamis Bio, NOV 3, 2026, View Source [SID1234674115])

Exelixis to Webcast Fireside Chats as Part of Upcoming Investor Conferences in November

On November 3, 2026 Exelixis, Inc. (Nasdaq: EXEL) reported that company management will participate in fireside chats at the following investor conferences in November:

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Guggenheim 3rd Annual Healthcare Innovation Conference: Exelixis is scheduled to present at 9:30 a.m. ET / 6:30 a.m. PT on Tuesday, November 10 in Boston.
Stifel 2026 Healthcare Conference: Exelixis is scheduled to present at 1:20 p.m. ET / 10:20 a.m. PT on Wednesday, November 11 in New York City.
UBS Global Biopharma Conference 2026: Exelixis is scheduled to present at 9:20 a.m. GMT / 4:20 a.m. ET / 1:20 a.m. PT on Tuesday, November 17 in London.
2026 Jefferies Global Healthcare Conference in London: Exelixis is scheduled to present at 1:30 p.m. GMT / 8:30 a.m. ET / 5:30 a.m. PT on Wednesday, November 18 in London.
To access the webcast links, log on to www.exelixis.com and proceed to the Event Calendar page under the Investors & News heading. Replays will also be available at the same location for at least 30 days.

(Press release, Exelixis, NOV 3, 2026, View Source [SID1234674114])

Avenzo Therapeutics to Participate at Upcoming Investor Conferences

On November 3, 2026 Avenzo Therapeutics, Inc. ("Avenzo"), a clinical-stage biotechnology company developing next-generation oncology therapies, reported that Athena Countouriotis, M.D., Chair, President and CEO, will participate in fireside chats and host investor meetings at the following upcoming investor conferences:

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3rd Annual Guggenheim Healthcare Innovation Conference
Event:

Fireside Chat

Date:

Tuesday, November 10, 2026

Presentation Time:

1:30 to 1:55 p.m. ET

Stifel 2026 Healthcare Conference
Event:
Fireside Chat

Date:

Wednesday, November 11, 2026

Presentation Time:

11:20 to 11:50 a.m. ET

Live webcasts of the fireside chats will be accessible on the company’s website, www.avenzotx.com, under the Events & Presentations section and an archived recording will be available on the website for 90 days following each presentation.

(Press release, Avenzo Therapeutics, NOV 3, 2026, View Source [SID1234674113])

PAQ Therapeutics to Present First Clinical Data for PT0253, a Selective KRAS G12D Degrader, in Late-Breaking Oral Presentation at the 2026 EORTC-NCI-AACR Symposium

On November 3, 2026 PAQ Therapeutics, a clinical-stage biotechnology company developing targeted protein degraders for KRAS-driven cancers with significant unmet medical need, reported that first clinical data for PT0253, its selective KRAS G12D degrader, will be presented in a late-breaking oral presentation at the 38th EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) Symposium on Molecular Targets and Cancer Therapeutics (ENA 2026), being held November 18–20 in Barcelona, Spain. The presentation will report findings from the company’s ongoing Phase 1 trial in patients with advanced solid tumors. PAQ will also present a poster describing the preclinical profile of PT0253.

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ENA 2026 Presentations

Late-Breaking Oral Presentation

Abstract 6LBA: PT0253, a selective KRAS G12D degrader, shows a differentiated safety profile and antitumor activity, including after prior (K)RAS therapy, in advanced solid tumors
Session: Plenary Session 6 – Proffered Papers: Advances in Targeting RAS
Date/Time: Friday, November 20, 2026, 12:36–12:44 p.m. CET
Authors: Leontios Pappas, William B. McKean, Alexander I. Spira (Presenting Author), Drew W. Rasco, Ildefonso I. Rodriguez-Rivera, Anthony Tolcher, Do-Youn Oh, Hye Jin Choi, Jin Won Kim, Joon Oh Park, Heung-Moon Chang, Hong Jae Chon, Huaixiang Hao, Lokesh Gakhar, Joseph Donahue, Adam Shilling, Eric Rubin, Nan Ji, Andrew P. Krivoshik

Poster Presentation

Abstract 320: PT0253 is a potent and selective KRAS G12D degrader for treatment of cancers
Session: New Drugs
Date: Friday, November 20, 2026
Poster Board: PB-112
Authors: Huaixiang Hao, Pengrong Yan, Yuxin Wang, Fei Feng, Lokesh Gakhar, Ning Yin, Hui Qiu, Ruoxi Lan, Nan Ji

(Press release, PAQ Therapeutics, NOV 3, 2026, View Source [SID1234674112])