On July 1, 2026 Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a transformative pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases, reported that management will participate in the following investor conferences in the third quarter of 2026.

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Leerink Partners Therapeutics Forum

Location: Boston, MA

Date: July 14th & 15th

Wells Fargo 21st Annual Healthcare Conference

Location: Boston, MA

Date: September 8th – 10th

12th Annual Cantor Fitzgerald Global Healthcare Conference

Location: New York, NY

Date: September 9th – 11th

H.C. Wainwright 28th Annual Global Investment Conference

Location: New York, NY

Date: September 14th – 16th

The Company may participate in a presentation or a fireside chat at these conferences. When available, a live webcast will be accessible under "Events & Presentations" in the Investors section of the Company’s website at www.fatetherapeutics.com. An archived replay of the webcast will be available for 30 days on the Company’s website following the event.

(Press release, Fate Therapeutics, JUL 1, 2026, View Source [SID1234669049])

On July 1, 2026 Alvotech (NASDAQ: ALVO; ALVO-SDB), a global biotechnology company specializing in the development and manufacture of biosimilar medicines for patients worldwide, reported that it has amended its existing credit agreement with funds managed by GoldenTree Asset Management LP and other existing lenders of Alvotech to provide a term loan facility of up to $75 million in additional capital.

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The financing further strengthens Alvotech’s financial position following the $165 million equity capital raise announced on June 18, 2026, and supports the continued execution of the company’s growth strategy, including advancing its biosimilar pipeline, supporting product launches and expanding global commercial operations. Including the equity financing and the undrawn term loan facility the company has secured access to $240 million in new capital.

"This financing provides additional flexibility as we continue to execute on our strategic priorities and support the next phase of growth for Alvotech," said Robert Wessman, founder and chairman of Alvotech. "The strong support we received from both existing shareholders and more than 40 new specialist healthcare investors in our recent equity offering, together with this additional financing, reflects growing confidence in Alvotech, our strategy and the opportunities ahead.

"Over the past several months we have achieved important milestones across our business, including the resubmission of key Biologics License Applications to the FDA, continued advancement of our pipeline including FDA acceptance of our BLA for a biosimilar to Entyvio, and the expansion of our global commercial footprint. These achievements reinforce our belief that we are building one of the world’s leading biosimilars companies.

"With approximately 30 biosimilar products in development and a growing portfolio of commercial opportunities, we see a significant opportunity to increase patient access to affordable biologic medicines around the world.

"Capital is the fuel that enables us to execute on that vision, and this financing further strengthens our ability to invest in growth and create long-term value for patients, partners and shareholders."

The financing builds on Alvotech’s existing relationship with GoldenTree, which has been a long-term financing partner to the company. It expands the company’s existing credit agreement by providing an additional $75 million term loan facility alongside the $100 million term loan facility announced in December 2025. It bears an interest rate of 12.50%, payable monthly in cash, and has a maturity date of December 31, 2027.

(Press release, Alvotech, JUL 1, 2026, View Source [SID1234669048])

On July 1, 2026 Telix Pharmaceuticals (ASX: TLX, NASDAQ: TLX, "Telix") reported the successful outcome of a Type B meeting with the United States (U.S.) Food and Drug Administration (FDA) to review the Part 1 safety and dosimetry data and Part 2 protocol design of the ProstACT Global Phase 3 trial of its therapeutic candidate TLX591-Tx (lutetium-177 (177Lu) rosopatamab tetraxetan) in metastatic castration resistant prostate cancer.

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The FDA has confirmed that the safety data from Part 1 of the study is sufficient to enable progression of Part 2 of ProstACT Global into the U.S. in which TLX591-Tx is administered in two doses, 14 days apart, in combination with one of three randomized standard of care (SOC) therapies: abiraterone, enzalutamide or docetaxel. The FDA and Telix also achieved alignment on the Part 2 clinical trial protocol, statistical analysis plan, and ongoing safety monitoring plan. The result is a consistent framework for study execution as enrollment continues internationally and expands into the U.S.

David N. Cade, MD, Group Chief Medical Officer, Telix, said, "This is an excellent outcome that enables submission of our IND amendment for initiation of Part 2 of ProstACT Global in the U.S. Part 2 continues to enroll strongly in regions where recruitment is open."

Neeraj Agarwal, MD, Professor of Medicine and Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, Salt Lake City, and ProstACT Global Principal Investigator and Steering Committee member, commented, "TLX591-Tx has the potential to redefine how radiopharmaceutical therapy is integrated into clinical practice. Because the complete treatment course is delivered over approximately two weeks, physicians can layer it into an existing regimen with minimal interruption, providing greater flexibility to sequence therapies while preserving future treatment options in patients with metastatic prostate cancer."

Initiation of Part 2 in the U.S. remains subject to the FDA’s review of an Investigational New Drug (IND) amendment. The IND amendment will also be aligned with a pending regulatory submission to initiate the ProstACT Global study in Europe. The trial continues to enroll patients in regions where Part 2 is approved1.

About ProstACT Global

ProstACT Global (ClinicalTrials.gov ID: NCT06520345) is an international, multicenter trial in two parts: Part 1, safety and dosimetry lead-in with 36 patients (complete); and Part 2, 2:1 randomized global expansion with an overall target enrollment of approximately 490 patients. Eligible patients must have confirmed progressive mCRPC assessed with a 68Ga-PSMA-11 PET2 imaging agent (such as Illuccix, kit for the preparation of gallium-68 (68Ga) gozetotide injection, or Gozellix, kit for the preparation of gallium-68 (68Ga) gozetotide injection) following prior treatment with one ARPI.

The antibody-based approach demonstrates differentiated targeting and pharmacology to other PSMA-targeted small molecule radioligand therapies (RLT). In contrast to these therapies3, collective long-term follow-up of patients administered with TLX591-Tx has not observed significant acute or delayed kidney toxicity, as the agent is hepatically (liver) excreted, a comparatively radioresistant organ4. TLX591-Tx also demonstrates minimal salivary and lacrimal gland uptake, reducing the prevalence of xerostomia (dry mouth) and dry eye, which are typical adverse effects of existing PSMA-targeted RLTs5. Additional information on the Phase 3 ProstACT Global study can be found at: View Source

(Press release, Telix Pharmaceuticals, JUL 1, 2026, View Source [SID1234669047])

On July 1, 2026 Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and a global leader in epigenetics, reported the successful completion of a €12 million gross capital increase through the issuance of 4,444,445 new ordinary shares, at a subscription price of €2.70 per share. This pricing represents a 14.15% discount to the five-day volume-weighted average price (VWAP), which was €3.1449, and a 12.68% discount to the June 30 closing price of €3.092 per share. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK. Banco Sabadell, S.A. acted as Agent Bank and Technical Pre-Financing Entity for the capital increase, while Gómez-Acebo & Pombo Abogados, S.L.P. acted as legal counsel to the Company.

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The funds raised will be used to:

Strengthen the Company’s balance sheet to support corporate development initiatives in anticipation of future partnership discussions.
Advance the clinical development of iadademstat for the treatment of acute myeloid leukemia.
Progress the other ongoing clinical programs in hematology and psychiatry.
Cover general and administrative expenses and financial obligations.

Dr. Carlos Buesa, Chief Executive Officer of Oryzon, said: "This funding comes at a particularly important time for Oryzon and strengthens our ability to execute our clinical strategy with greater confidence. The progress of our acute myeloid leukemia program is attracting increasing attention across the international oncology ecosystem, including among leading experts, pharmaceutical companies, and specialized investors. With this support, we gain financial flexibility to accelerate our priority programs while continuing to explore strategic opportunities that can maximize the value of our platform."

Agreement with the Social Impact Fund managed by COFIDES

Oryzon has also entered into a share subscription agreement with the Social Impact Fund, managed by Compañía Española de Financiación del Desarrollo (COFIDES), S.A., S.M.E., and attached to the Ministry of Inclusion, Social Security and Migration, under Spain’s Recovery, Transformation and Resilience Plan, financed by the European Union through the NextGenerationEU programme.

Under the terms of the agreement, the Social Impact Fund has committed, as an anchor investor, to subscribe in the future for newly created Oryzon shares for a total investment amount (nominal plus issue premium) of €25 million, subject to certain corporate, financial, business, and impact-related conditions.

This commitment will apply to any future capital increase that Oryzon may undertake within six months of the execution of the share subscription agreement. This period may be extended by mutual agreement between the parties.

The Company has undertaken to use the proceeds to fund research and development activities directly or indirectly related to the development of products in the field of the central nervous system, as well as in oncology and hematology. In addition, at least 40% of the proceeds must be allocated to the development of medicines addressing unmet medical needs in mental health, in particular to the Company’s program in borderline personality disorder and other psychiatric conditions.

Dr. Buesa added: "The partnership with COFIDES’ Social Impact Fund represents far more than a financial commitment; it is a recognition of the transformative potential of our mental health programs. The validation of this project by such a prestigious institution—from scientific, business, and social impact perspectives—reinforces our conviction that Oryzon can play a significant role in an area where unmet medical needs remain substantial. This agreement enhances our credibility, raises our visibility, and strengthens our ability to accelerate the development of innovative therapies for psychiatric disorders. Having a prestigious institutional partner with international standing further reinforces the project’s credibility and facilitates engagement with specialized international investment funds."

(Press release, Oryzon, JUL 1, 2026, View Source [SID1234669046])

On July 1, 2026 92Bio, Inc. (www.92biotech.com), a clinical-stage biotechnology company developing next-generation T-cell engaging antibodies (TCEs), reported dosing of the first patient in a Phase 1 clinical trial evaluating NTB-928 for the treatment of platinum-resistant ovarian cancer. The trial is being conducted at multiple US sites, with the first patient dosed at START New York-Long Island under the direction of Principal Investigator Dr. Geraldine O’Sullivan Coyne, MD.

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NTB-928 combines an affinity-tuned anti-CD3 moiety with an avidity-dependent FOLR1-binding arm for tumor versus normal selectivity. The dual-mechanism design enables potent killing of FOLR1-overexpressing ovarian cancer cells while sparing normal tissues that express trace FOLR1—a key limitation of conventional approaches targeting this antigen. Notably, FOLR1 is overexpressed in greater than 75% of ovarian cancer. Preclinical data supporting NTB-928’s differentiated selectivity profile have been published in Oncoimmunology (Avanzino et al., 2022).

The ongoing Phase 1, single-arm, open-label trial utilizes a Bayesian Optimal Interval dose-escalation design with backfill (BOIN-BF) to evaluate the safety, tolerability, and preliminary activity of NTB-928.

"Dosing the first patient in this study is a defining moment for 92Bio," said Ben Buelow, MD, PhD, Chief Executive Officer of 92Bio. "NTB-928 was purpose-built to solve the selectivity challenge that has constrained FOLR1 targeted T-cell engagers in ovarian cancer. Its unique combination of affinity-tuned CD3 engagement and avidity-dependent FOLR1 binding positions it specifically as a best-in-class candidate for patients with ovarian cancer, and generally for FOLR1-positive malignancies beyond that."

"The initiation of this study represents an important step forward in evaluating a novel approach for patients with platinum-resistant ovarian cancer, where significant unmet needs remain," said Geraldine O’Sullivan Coyne, MD, Principal Investigator at START New York-Long Island who dosed the first patient. "We are proud to support the clinical development of NTB-928 and grateful for the strong collaboration between START, 92Bio, and Northwell Health Cancer Institute. Milestones like this are only possible through a shared commitment to advancing research and expanding opportunities for patients."

About NTB-928

NTB-928 is a fully human bispecific T-cell engaging antibody targeting FOLR1 and CD3. Its selectivity derives from two synergistic design features: an affinity-tuned anti-CD3 arm that drives potent anti-tumor T-cell activation with reduced cytokine secretion, and a bivalent FOLR1-binding arm that confers avidity-dependent binding to tumor cells overexpressing FOLR1 but not to normal cells expressing trace FOLR1. Neither feature alone is sufficient for selectivity; both are required. In preclinical studies, NTB-928 demonstrated robust tumor clearance in vitro, ex vivo and in vivo with a favorable safety profile (Avanzino BC et al., Oncoimmunology, 2022; doi: 10.1080/2162402X.2022.2113697).

(Press release, 92Bio, JUL 1, 2026, View Source [SID1234669045])