AIM ImmunoTech Participates in the Virtual Investor ‘Why Now’ On-Demand Conference

On August 27, 2026 AIM ImmunoTech Inc. (NYSE American: AIM) ("AIM" or the "Company") reported that it participated in the Virtual Investor "Why Now" on-demand conference.

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During the webcast, AIM Chief Executive Officer Thomas Equels presented the Company’s investment thesis, highlighting why he believes now is a pivotal time for AIM. The presentation discusses the Company’s progress advancing Ampligen through the Phase 2 DURIPANC clinical trial in metastatic pancreatic cancer, including successful completion of enrollment ahead of schedule, Ampligen dosing of the final patient and the anticipated transition into primary endpoint evaluation in the fourth quarter of 2026, with topline results expected in the first quarter of 2027.

The video webcast is now accessible for on-demand viewing here.

JTC Team and Virtual Investor Co. are paid consultants to AIM ImmunoTech Inc. JTC Team and Virtual Investor Co. are investor relations and corporate communications firms. Any content included in this release shall not be construed as an offer to purchase securities of AIM ImmunoTech Inc. Interested parties are responsible for conducting their own due diligence and are encouraged to review the Company’s website and the SEC website for the latest information and filings on the Company.

(Press release, AIM ImmunoTech, AUG 27, 2026, View Source [SID1234670377])

Faron Announces First Patient Enrolled in BEXAR Investigator-Initiated Trial

On August 27, 2026 Faron Pharmaceuticals Ltd. (AIM: FARN, First North: FARON), a global, clinical-stage biopharmaceutical company focused on creating innovative cancer treatments that leverage the patient’s own immune system, reported that the first patient has been enrolled in the Phase 1b/2 BEXAR investigator-initiated trial.

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The BEXAR trial evaluates Faron’s lead asset, bexmarilimab, in combination with standard-of-care doxorubicin as a first-line treatment for patients with metastatic soft-tissue sarcoma.

The trial is sponsored by the international oncology research company MEDSIR and currently conducted at six hospitals across Spain, led by the Vall d’Hebron University Hospital in Barcelona. The Phase 1b/2 BEXAR trial is designed to evaluate the safety and tolerability of bexmarilimab in combination with doxorubicin in the Phase 1b stage, followed by a contingent randomized Phase 2 assessment of preliminary efficacy versus doxorubicin alone.

Dr. César Serrano, Group Leader of the Sarcoma Translational Research Program at the Vall d’Hebron Institute of Oncology and a member of the Sarcoma Faculty of the European Society of Medical Oncology (ESMO) (Free ESMO Whitepaper), and scientific and clinical lead of the trial said, "Metastatic soft-tissue sarcoma has seen limited therapeutic progress in decades, and remains particularly difficult to treat. By combining doxorubicin with bexmarilimab, we aim to test whether reprogramming immunosuppressive macrophages can help ignite an anti-tumor response and translate into clinical benefit."

This enrollment marks the first patient treated with bexmarilimab in the BEXAR trial and the first clinical evaluation of an anti-Clever-1 strategy in combination with doxorubicin in patients with soft-tissue sarcoma. Soft-tissue sarcomas are highly aggressive malignancies and many subtypes are characterized by an immunologically inactive tumor microenvironment heavily dominated by immunosuppressive macrophages. These tumors express some of the highest levels of Clever-1, the target receptor of bexmarilimab, providing a strong mechanistic rationale for this combination strategy.

Dr. Petri Bono, Chief Medical Officer at Faron, commented, "The initiation of patient enrollment in the BEXAR trial is a significant milestone for our solid tumor strategy. Sarcomas express exceptionally high levels of Clever-1, providing a strong biological rationale for investigating an anti-Clever-1 approach in this setting. By combining bexmarilimab with chemotherapy, this trial is the first opportunity to generate clinical evidence for bexmarilimab’s mechanism in soft-tissue sarcomas. If this combination shows evidence of synergy, it could support the rationale for exploring bexmarilimab with other chemotherapy backbones across Clever-1-expressing tumor types. We are proud to support the world-class team at Vall d’Hebron and look forward to the data this trial will generate."

About bexmarilimab

Bexmarilimab is Faron’s wholly owned, investigational immunotherapy designed to overcome resistance to existing treatments and optimize clinical outcomes by targeting myeloid cell function. It binds to Clever-1, a receptor on immunosuppressive macrophages that helps cancer evade the immune system. By targeting Clever-1, bexmarilimab reprograms the tumor microenvironment to ignite a potent anti-tumor immune response.

(Press release, Faron Pharmaceuticals, AUG 27, 2026, View Source [SID1234670362])

Oncoinvent presents first half 2026 results

On August 27, 2026 Oncoinvent reported that its management will give an online presentation to investors, analysts and the press at 10:00am CEST. It will be possible to submit questions during the presentation.

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Presenters: CEO Oystein Soug, CFO Ramzi Amri
Time: 10:00am CEST
Webcast link: View Source
A recording of the webcast will be made available on www.oncoinvent.com after the live sending.

Highlights:

Achieved 50% recruitment milestone in Phase 2 ovarian cancer study of Radspherin
Added four new clinical sites to Oncoinvent’s Phase 2 trial
Presented positive 24-month follow-up data from Phase 1 ovarian cancer trial of Radspherin at 27th Congress of the European Society of Gynaecological Oncology (ESGO) 2026
Appointed Dr Ramzi Amri as Chief Financial Officer (CFO)
Secured new patent expanding protection for Radspherin
Post-period highlights:

Announced publication of normal tissue dosimetry results in Journal of Nuclear Medicine
Announced abstracts accepted at two major scientific conferences:
European Society for Medical Oncology (ESMO) (Free ESMO Whitepaper) Congress 2026 in Madrid, Spain (23-27 October)
European Association of Nuclear Medicine (EANM) Annual Congress 2026 in Vienna, Austria (17-21 October)
Oystein Soug, CEO, commented: "We entered the year with a clear focus on accelerating patient recruitment, and I am pleased to say that these efforts are delivering tangible results. Recruitment momentum accelerated significantly during the first half of the year, reinforcing our confidence in the potential of Radspherin to address a significant unmet medical need in ovarian cancer."

Key financial figures

AMOUNTS IN 1 000 NOK 1H 2026 1H 2025 FY2025
Total operating revenue 8 203 11 960 28 069
Total operating expenses (77 195) (63 978) (186 399)
Operating profit (-loss) (68 992) (52 018) (158 330)
Cash 108 839 77 412 179 670
Earnings per share (EPS) (15.20) (54.01) (125.13)
# Shares 4 478 412 962 544 1 239 249
Employees (FTEs) 42 36 44
The interim financial information has not been subject to audit

Reporting material:

Oncoinvent 1H26 report
Oncoinvent 1H26 presentation
The reporting material are also available in the Investor Relations section of the Company’s website at www.oncoinvent.com.

(Press release, Oncoinvent, AUG 27, 2026, https://www.oncoinvent.com/press-release/oncoinvent-presents-first-half-2026-results/ [SID1234670350])

Jazz Pharmaceuticals Announces Private Offering of $1.0 Billion of Exchangeable Senior Notes due 2032 and Concurrent Ordinary Share Repurchases

On August 26, 2026 Jazz Pharmaceuticals plc (Nasdaq: JAZZ) ("Jazz Pharmaceuticals") reported that Jazz Investments I Limited, its wholly-owned subsidiary (the "Issuer"), intends to offer, subject to market conditions and other factors, $1.0 billion aggregate principal amount of exchangeable senior notes due 2032 (the "notes") in a private offering (the "offering") to qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act"). The Issuer also intends to grant the initial purchasers of the notes the right to purchase, exercisable within a 13-day period from, and including the initial issue date of the notes, up to an additional $150.0 million aggregate principal amount of notes.

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The notes will be exchangeable under certain conditions. Upon exchange of the notes, the Issuer will pay cash up to the aggregate principal amount of the notes to be exchanged and pay or deliver, as the case may be, cash, ordinary shares of Jazz Pharmaceuticals ("ordinary shares") or a combination of cash and ordinary shares, at the Issuer’s election, in respect of the remainder, if any, of the Issuer’s exchange obligation in excess of the aggregate principal amount of the notes exchanged. The interest rate, initial exchange rate and other terms of the notes will be determined at the time of pricing of the offering.

The notes will accrue interest payable semiannually in arrears. The notes will be fully and unconditionally guaranteed, on a senior unsecured basis, by Jazz Pharmaceuticals. The notes and the guarantee will be the Issuer’s and Jazz Pharmaceutical’s senior unsecured obligations and will rank senior in right of payment to all of the Issuer’s and Jazz Pharmaceutical’s future indebtedness that is expressly subordinated in right of payment to the notes; equal in right of payment with all of the Issuer’s and Jazz Pharmaceutical’s existing and future liabilities that are not so subordinated (other than certain liabilities that are preferred under Bermuda or Irish law); effectively junior to any of the Issuer’s or Jazz Pharmaceutical’s existing and future secured indebtedness to the extent of the value of the assets securing such indebtedness and to certain liabilities that are preferred under Bermuda or Irish law; and structurally junior to all existing and future indebtedness and other liabilities (including trade payables) of the Issuer’s and Jazz Pharmaceutical’s subsidiaries.

Jazz Pharmaceuticals, together with its consolidated subsidiaries, expects to use the net proceeds from the offering for general corporate purposes.

Jazz Pharmaceuticals also expects to repurchase up to $225.0 million of its ordinary shares from purchasers of the notes in privately negotiated transactions with or through one of the initial purchasers or its affiliate concurrently with the pricing of the offering (the "concurrent ordinary share repurchases"). Jazz Pharmaceuticals expects the purchase price per ordinary share repurchased in any such concurrent ordinary share repurchases to equal the closing price per ordinary share on the date of the offering.

To the extent Jazz Pharmaceuticals effects any such concurrent ordinary share repurchases, it will pay for such repurchases with existing cash on hand and such repurchases will be effected as part of Jazz Pharmaceuticals’ share repurchase program announced in July 2024. Accordingly, any such concurrent ordinary share repurchases will reduce the remaining amount authorized under the share repurchase program. No assurance can be given as to how many, if any, of the ordinary shares will be repurchased or the terms on which they will be repurchased.

The concurrent ordinary share repurchases could increase, or reduce the size of any decrease in, the market price of the ordinary shares, including concurrently with the pricing of the notes, resulting in a higher effective exchange price for the notes. Jazz Pharmaceuticals cannot predict the magnitude of such market activity or the overall effect the concurrent ordinary share repurchases will have on the price of the notes offered in the offering or the market price of the ordinary shares. This press release is not an offer to repurchase the ordinary shares, and the offering of the notes is not contingent upon the repurchase of any ordinary shares.

None of the notes, the guarantee or the ordinary shares issuable upon exchange of the notes, if any, have been registered under the Securities Act or the securities laws of any other jurisdiction, and, unless so registered, may not be offered or sold in the United States absent registration or an applicable exemption from, or in a transaction not subject to, the registration requirements of the Securities Act and other applicable securities laws.

This press release does not and shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of the securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state or jurisdiction.

(Press release, Jazz Pharmaceuticals, AUG 26, 2026, View Source [SID1234670443])

Tvardi Therapeutics to Participate in Upcoming Investor Events

On August 26, 2026 Tvardi Therapeutics, Inc. ("Tvardi") (NASDAQ: TVRD), a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting STAT3 to treat inflammatory and proliferative diseases, reported that management will participate in the following upcoming investor events:

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Wells Fargo 21st Annual Healthcare Conference
Format: 1-on-1 Meetings
Date: Wednesday, September 9, 2026
Location: Boston, MA

2026 Cantor Global Healthcare Conference
Format: Fireside Chat and 1-on-1 Meetings
Date: Thursday, September 10, 2026
Time: 10:55 AM ET
Location: New York, NY

H.C. Wainwright 28th Annual Global Investment Conference
Format: Company Presentation and 1-on-1 Meetings
Date: Monday, September 14, 2026
Time: 4:30 PM ET
Location: New York, NY

The corporate presentation and H.C. Wainwright webcast will be accessible on Tvardi Investors’ website. A replay of the webcast will be available for approximately 90 days following the conference.

(Press release, Tvardi Therapeutics, AUG 26, 2026, View Source [SID1234670376])