Okomera Announces a Commercial Agreement With Servier to Use Its Tumor Miniaturization Technology for Cancer Research

On October 21, 2026 Okomera, a TechBio company pioneering personalized cancer care through a proprietary technology platform combining tumor mini-avatars, microfluidics, and AI-powered imaging, reported the signing of a commercial agreement with Servier, an independent international pharmaceutical group, to use its technology in the development of new cancer treatments.

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With more than 90% of oncology drug candidates never reaching the market, identifying early on the therapeutic approaches most likely to succeed is a critical challenge for the pharmaceutical industry. Okomera’s technology helps precisely reduce this attrition, by steering development toward candidates that demonstrated real, measurable activity against tumors.

This collaboration marks an important milestone for Okomera, which is signing its first commercial agreement with an international pharmaceutical group. Under the terms of the agreement, Servier will operate Okomera’s platform fully independently. Its teams will be able to generate standardized spheroid cultures, assess the response of these "miniaturized tumor avatars" to potential treatments, and generate actionable data on key biological mechanisms to support the development of new therapies, notably for pancreatic cancer and glioblastoma.

Nicolas Molinié, Group Leader Target Discovery at Servier, said: "Okomera’s technology allows us to easily generate standardized data from human tumor models. The integrated platform will help us better characterize treatment response mechanisms and identify faster the most promising therapeutic avenues."

Silvère Lucquin, CEO of Okomera, added: "We are particularly proud of this collaboration with Servier, which underscores the value of our platform in meeting the needs of both industry and research teams developing new therapies. This agreement is the result of several years of R&D efforts and reflects the growing adoption of our technology."

Okomera deploys its technology across the entire therapeutic innovation value chain: from preclinical research, as with Servier, to clinical trials and patient care by clinicians. Using patient biopsies, its miniaturization technology reproduces tumor behavior and analyzes how tumors respond to different treatments. Designed as a decentralized laboratory, it delivers the capabilities of a state-of-the-art infrastructure within a single machine, enabling users to independently manage the entire workflow, from culture generation to actionable data production.

Today, nearly one in two oncology patients does not respond to their initial treatment. By placing patient biology at the heart of therapeutic decision-making, Okomera is paving the way for a new generation of precision medicine.

(Press release, Servier, OCT 21, 2026, View Source [SID1234673657])

Arcus Biosciences Announces Pricing of $250 Million Public Offering of Common Stock

On October 21, 2026 Arcus Biosciences, Inc. (NYSE: RCUS), a late clinical-stage biopharmaceutical company focused on developing differentiated molecules and combinations for the treatment of cancer and immune diseases, reported the pricing of an underwritten public offering of 14,285,715 shares of its common stock at a price to the public of $17.50 per share. Gross proceeds to Arcus Biosciences from the offering are expected to be $250.0 million, before deducting underwriting discounts and commissions and offering expenses. All of the shares of common stock are being offered by Arcus Biosciences. In addition, Arcus Biosciences has granted the underwriters a 30-day option to purchase up to 2,142,857 additional shares of its common stock at the public offering price, less underwriting discounts and commissions. The offering is expected to close on October 23, 2026, subject to customary closing conditions.

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Jefferies, Leerink Partners, TD Cowen, Evercore ISI and Mizuho are acting as joint book-running managers for the offering.

A shelf registration statement relating to these securities was filed with the U.S. Securities and Exchange Commission (SEC) on February 25, 2026, and automatically became effective upon filing. This offering is being made solely by means of a prospectus. A copy of the final prospectus supplement and the accompanying prospectus relating to this offering may be obtained for free by visiting EDGAR on the SEC’s website at www.sec.gov. Alternatively, a copy of the final prospectus supplement and the accompanying prospectus relating to this offering may be obtained by contacting: Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, New York, New York 10022, or by telephone at (877) 821-7388, or by email at [email protected]; Leerink Partners LLC, Attention: Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, or by telephone at (800) 808-7525 ext. 6105, or by email at [email protected]; or TD Securities (USA) LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, or by email at [email protected].

This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.

(Press release, Arcus Biosciences, OCT 21, 2026, View Source [SID1234673656])

Innate Pharma to Participate in the Stifel Healthcare Conference and Jefferies Global Healthcare Conference

On October 21, 2026 Innate Pharma SA (Euronext Paris: IPH; Nasdaq: IPHA) ("Innate" or the "Company"), a clinical-stage biotechnology company developing immunotherapies for cancer patients, reported that members of its executive team will participate in the following investor conferences:

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Stifel Healthcare Conference

Dates: November 10–12, 2026
Location: New York, United States
Fireside chat:

Date: November 10, 2026
Time: 2:00 p.m. ET / 8:00 p.m. CET
To enter the live webcast, please click here
The link to access the live webcast of the presentation will be available on the Events page of the Investors section of Innate Pharma’s website. A replay of the presentation will be available following the event.

Jefferies Global Healthcare Conference

Dates: November 16-19, 2026
Location: London, United Kingdom

(Press release, Innate Pharma, OCT 21, 2026, View Source [SID1234673655])

Personalis NeXT Personal® Data Showcasing Ultrasensitive MRD to be Presented at ESMO 2026

On October 21, 2026 Personalis, Inc. (Nasdaq: PSNL), a leader in advanced genomics for precision oncology, reported that two oral presentations and two poster presentations featuring its NeXT Personal ultrasensitive circulating tumor DNA (ctDNA) test will be presented at the European Society for Medical Oncology (ESMO) (Free ESMO Whitepaper) Congress 2026, taking place October 23-27 in Madrid, Spain. Highlights include a late-breaking oral presentation of NeXT Personal data for the C-POST Phase 3 study in cutaneous squamous cell carcinoma, as well as a Rapid Oral presentation from B-STRONGER-1, a prospective, multicenter study evaluating NeXT Personal for detecting molecular residual disease in patients with early-stage triple-negative breast cancer receiving neoadjuvant therapy.

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"B-STRONGER-1 builds on our earlier work in triple-negative breast cancer demonstrating the use of ultrasensitive MRD testing for monitoring neoadjuvant therapy response," said Richard Chen, MD, President and Chief Medical Officer of Personalis. "We are also excited to see NeXT Personal data presented from biopharma in new indications like cutaneous squamous cell carcinoma as we continue to expand evidence around NeXT Personal for a broad range of solid tumors."

Presentation Schedule

Late-Breaking Oral Presentation

Title: C-POST phase 3 trial of adjuvant (adj) cemiplimab (cemi) vs placebo (pbo) for high-risk cutaneous squamous cell carcinoma (CSCC): Updated overall survival (OS) and outcomes from circulating tumour DNA (ctDNA) analyses
Presenter: Danny Rischin, M.D.; Peter MacCallum Cancer Centre
Abstract: LBA59 | Session: Rapid Oral – Melanoma and Other Skin Tumours
Time: Sun, 10/25/2026, 10:42 – 10:47 CET
Location: Granada Auditorium – Hall 4
Rapid Oral Presentation – B-STRONGER-1

Title: Ultrasensitive monitoring of early ctDNA dynamics during neoadjuvant treatment in early-stage triple-negative breast cancer: Pre-interim results from the B-STRONGER-I study
Presenter: Carlos Barcenas, M.D.; The University of Texas MD Anderson Cancer Center
Abstract: 540RO | Session: Rapid Oral – Breast Cancer, Early Stage
Time: Fri, 10/23/2026, 16:42 – 16:47 CEST
Location: Alicante Auditorium – Hall 6
Poster Presentations

Title: Ultrasensitive ctDNA kinetics predict early immunotherapy response and complement radiographic assessment in advanced cancer. (UC San Diego). Abstract # 4280P | Session: Translational Research and Biomarkers | Time: Fri, 10/23/2026, 15:15 – 16:00 CEST | Location: Poster Area – Hall 5
Title: Circulating tumour DNA (ctDNA), cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) associate with survival outcomes in patients with platinum- resistant ovarian cancer (PROC) treated with ubamatamab (uba). (Yonsei University Health System). Abstract # 1957P | Session: Investigational Immunotherapy | Time: Sat, 10/24/2026, 12:00 – 12:45 CEST | Location: Poster Area – Hall 5

(Press release, Personalis, OCT 21, 2026, View Source [SID1234673654])

Foundation Medicine and Joint Collaborators to Present 12 Abstracts at the ESMO Congress 2026

On October 21, 2026 Foundation Medicine, Inc., a global, patient-focused precision medicine company, reported the acceptance of 12 abstracts for presentation at the European Society for Medical Oncology (ESMO) (Free ESMO Whitepaper) Congress 2026, scheduled for October 23-27, 2026, in Madrid, Spain. These presentations cover key topics such as MTAP loss, the clinical impact of clonal hematopoiesis (CH), and the expanded utility of circulating tumor DNA (ctDNA) tumor fraction.

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In addition to 10 poster presentations, Foundation Medicine’s research will be featured in two Rapid Oral Sessions:

2218RO – Distinguishing clonal hematopoiesis (CH) from tumor homologous recombination repair (HRR) alterations in liquid biopsy: implications for PARP inhibitor (PARPi) use in metastatic castration-resistant prostate cancer (mCRPC)
Friday, October 23 at 13:00 CEST in Bilbao Auditorium – Hall 3
2219RO – Utility of ctDNA tumor fraction (TF) as a prognostic biomarker in TALAPRO-3: Phase 3 study of talazoparib (TALA) + enzalutamide (ENZA) vs placebo (PBO) + ENZA in patients (pts) with homologous recombination repair (HRR) gene–mutated metastatic castration-sensitive prostate cancer (mCSPC)
Friday, October 23 at 13:00 CEST in Bilbao Auditorium – Hall 3
Foundation Medicine will also host a series of expert-led booth talks in its booth 1030 in Hall 10:

Saturday, October 24
13:00 – 13:15 CEST – Don’t Miss the Loss: Unlocking MTAP, PTEN & Others Through Robust Copy Number Detection
13:25 – 13:40 CEST – Breaking the Sensitivity Floor: The Science of Ultra-Sensitive MRD
13:50 – 14:05 CEST – Detect MTAP Loss More Often in Your Clinical Trials: Don’t Miss the Signal
14:15 – 14:30 CEST – Don’t Miss Fusions and Complex Variants with FoundationOneRNA
Sunday, October 25
13:00 – 13:15 CET – Translating Ultra-Sensitive MRD to Clinical Practice: Detection and Monitoring of ctDNA Using Structural Variants
13:30 – 13:45 CET – Don’t Miss the Loss: Unlocking MTAP, PTEN & Others Through Robust Copy Number Detection
14:00 – 14:15 CET – Redefining the Standard in MRD: Structural Variants & Digital PCR for Ultra Sensitivity & High Specificity
Monday, October 26
13:00 – 13:15 CET- The Role of Longitudinal ctDNA Testing in Early and Advanced Stage Cancer
13:30 – 13:45 CET – Don’t Miss the Loss: Unlocking MTAP, PTEN & Others Through Robust Copy Number Detection
14:00 – 14:15 CET – HRD Signature Without Limits: Go Beyond Ovarian
To learn more, visit Foundation Medicine in person at booth 1030 in Hall 10 or book a meeting at View Source

Full List of Foundation Medicine’s Abstracts at ESMO (Free ESMO Whitepaper) Congress 2026

Presentation Number

Title

Product

Friday, October 23

2218RO

Distinguishing clonal hematopoiesis (CH) from tumor homologous recombination repair (HRR) alterations in liquid biopsy: implications for PARP inhibitor (PARPi) use in metastatic castration-resistant prostate cancer (mCRPC)

FoundationOneLiquid CDx

2219RO

Utility of ctDNA tumor fraction (TF) as a prognostic biomarker in TALAPRO-3: Phase 3 study of talazoparib (TALA) + enzalutamide (ENZA) vs placebo (PBO) + ENZA in patients (pts) with homologous recombination repair (HRR) gene–mutated metastatic castration-sensitive prostate cancer (mCSPC)

FoundationOne Liquid CDx, FoundationOneMonitor

4294P

The Tumor-Agnostic (TA) Therapy Biomarker Landscape: Established and Emerging Markers Across 385,420 Solid Tumors

FoundationOneCDx

4304P

Comprehensive Genomic Profiling in Lacrimal Duct Carcinoma Reveals HER2-Driven Biology and Emerging Therapeutic Targets

FoundationOne CDx

4762P

Homologous Recombination Signature (HRDsig) in Adenocarcinoma (ACB) and Urachal Carcinoma (UrCA) of the Bladder: Implications for PARP Inhibitor (PARPi) Treatment

FoundationOne CDx

4308P

Genomic Landscape of KRAS G12D Mutant Non-Small Cell Lung Cancer (NSCLC) and Comparison with KRAS non-G12D Mutant and KRAS Wild Type Cases

FoundationOne CDx

4372P

MTAP Loss and HPV Status in Head and Neck Squamous Cell Carcinoma (HNSCC): A Genomic Landscape Study

FoundationOne CDx

2232P

Longitudinal ctDNA tumor fraction (TF) as a prognostic biomarker in bone-dominant metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 ± olaparib: Results from the phase 2 COMRADE trial

FoundationOne Liquid CDx,

FoundationOne Monitor

4750P

Overall survival (OS) and mature safety results of SURE-02, a phase 2 study of neoadjuvant Sacituzumab govitecan (SG) plus pembrolizumab (Pembro), followed by response-adapted bladder sparing and adjuvant Pembro, in patients with muscle-invasive bladder cancer (MIBC)

N/A

4283P

ctDNA tumor fraction captures tumor biology and predicts resistance to systemic therapy across solid tumors and NSCLC

FoundationOne Liquid CDx

Monday, October 26

3765P

Homologous Recombination Signature (HRDsig) in Angiosarcoma (AngSarc)

FoundationOne CDx

2628P

Genomic and Biomarker Landscape of MTAP loss/KRAS G12D mutant vs. MTAP loss/KRAS non-mutated Advanced NSCLC

FoundationOne CDx

(Press release, Foundation Medicine, OCT 21, 2026, View Source [SID1234673653])