On May 14, 2025 Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious hematologic diseases, reported that it will present data from multiple programs in its hematology portfolio at the upcoming European Hematology Association (EHA) (Free EHA Whitepaper) 2025 Congress, which will be held in Milan, Italy on June 12-15, 2025 (Press release, Disc Medicine, MAY 14, 2025, View Sourcenews-releases/news-release-details/disc-medicine-announces-multiple-presentations-across-2" target="_blank" title="View Sourcenews-releases/news-release-details/disc-medicine-announces-multiple-presentations-across-2" rel="nofollow">View Source [SID1234653790]).
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"As we progress toward major company milestones in the second half of 2025, this year’s EHA (Free EHA Whitepaper) presentations showcase steady progress across our pipeline," said John Quisel, J.D., Ph.D., President and Chief Executive Officer of Disc. "We plan to share data from the HELIOS long-term extension trial, further supporting bitopertin’s potential profile as the first disease-modifying treatment for EPP. We’ll also present additional durability data and new analyses from the Phase 1b study of DISC-0974 in patients with MF anemia, along with new data from DISC-3405 in healthy volunteers that supports its progression into a Phase 2 study in polycythemia vera in the first half of this year and its broader potential in diseases of iron overload."
Management will host a call to review the presented data on June 16 at 8:00 am ET. Please register for the event on the Events and Presentations page of Disc’s website (View Source)
Details of Presentations and Abstracts
The full abstracts are now available through the EHA (Free EHA Whitepaper) conference website. Pursuant to Disc Medicine practice, the abstracts published today contain previously presented data, and new data and analyses are reserved for presentation at the conference.
Bitopertin Poster Presentations:
Abstract Number: PS2210
Title: Results from the HELIOS Study: A Phase 2, Open-Label, Long-Term Extension Study of Bitopertin in Erythropoietic Protoporphyria
Date / Time: Saturday, June 14, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Melanie Chin
DISC-0974 Poster Presentations:
Abstract Number: PF856
Title: A Phase 1b/2 Study of DISC-0974, An Anti-Hemojuvelin Antibody, In Patients with Myelofibrosis and Anemia
Date / Time: Friday, June 13, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Sima Bhatt
Abstract Number: PS1845
Title: DISC-0974 (An Anti-Hemojuvelin Antibody) in Non-Transfusion-Dependent Patients with Myelofibrosis: Laboratory Correlates of Major Anemia Response
Date / Time: Saturday, June 14, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Ayalew Tefferi
Abstract Number: PS1814
Title: Anti-Hemojuvelin Monoclonal Antibody Further Enhances Hematologic Response to ESA and/or Luspatercept in Mice
Date / Time: Saturday, June 14, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Min Wu
DISC-3405 Poster Presentations:
Abstract Number: PF1216
Title: An Iron Pulse Study to Assess Oral Iron Absorption Following Treatment with DISC-3405 in Healthy Volunteers
Date / Time: Friday, June 13, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Guowen Liu
Abstract Number: PS2207
Title: Single- and Multiple- Ascending Doses of DISC-3405, A Recombinant Humanized Antibody Targeting TMPRSS6, Increased Hepcidin and Reduced Iron and Hematocrit in Healthy Volunteers
Date / Time: Saturday, June 14, 6:30 pm CEST / 12:30 pm ET
Presenting Author: Marcus Carden