On November 14, 2025 Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of emavusertib (CA-4948), an orally available, small molecule IRAK4 inhibitor, reported that Curis will report emavusertib and BTKi clinical data in Primary CNS Lymphoma (PCNSL) and Secondary CNS Lymphoma (SCNSL) in three presentations and preclinical data on emavusertib in an oral presentation at the 30th Annual Meeting of the Society for Neuro-Oncology (SNO) on November 19-23:
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November 21, 2025 – 4:30 PM ET (11:30 AM HT)
Format:
Poster Presentation
Presenter:
Dr. Christian Grommes, Memorial Sloan Kettering Cancer Center, NY, NY
Title:
Analysis of Genetic Mutation Profile and CNS Pharmacokinetics in Relapsed/Refractory Primary CNS Lymphoma Patients Responding to Novel Emavusertib (IRAK4i) and BTKi Combination
Format:
Poster Presentation
Presenter:
Dr. Lakshmi Nayak, Dana-Farber Cancer Institute, Boston, MA
Title:
Preliminary Safety and Efficacy of Emavusertib (CA-4948) in Combination with Ibrutinib in Relapsed/Refractory Primary Central Nervous System Lymphoma Patients
November 22, 2025 – 4:45 PM ET (11:45 AM HT)
Format:
Rapid Oral Presentation
Presenter:
Dr. Christian Grommes, Memorial Sloan Kettering Cancer Center, NY, NY
Title:
Analysis of Genetic Mutation Profile and CNS Pharmacokinetics in Relapsed/Refractory Primary CNS Lymphoma Patients Responding to Novel Emavusertib (IRAK4i) and BTKi Combination
Format:
Poster Presentation
Presenter:
Cecilia A. Merrigan, APRN, CNP, DNP, Mayo Clinic, Rochester, MN
Title:
Promising Efficacy Signal in Secondary CNS Lymphoma Patients Treated with Emavusertib and Ibrutinib
November 23, 2025 – 3:24 PM ET (10:24 AM HT)
Format:
Oral Presentation
Presenter:
Christina von Roemeling, Ph.D., University of Florida, Gainesville, FL
Title:
Targeting Myddosome Signaling to Improve Immunotherapy in Melanoma Brain Metastases
(Press release, Curis, NOV 14, 2025, View Source [SID1234659967])