Agenus Announces Data from Phase II Study of BOT+BAL in Combination with agent-797 in PD-1 Refractory Gastroesophageal Cancer to be Presented at AACR 2026

On April 3, 2026 Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, reported that data from an investigator-initiated Phase II trial conducted at Memorial Sloan Kettering Cancer Center will be presented at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting, taking place April 17–22, 2026, in San Diego, CA.

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The study evaluates botensilimab (BOT) and balstilimab (BAL) in combination with agenT-797, an allogeneic iNKT cell therapy developed by MiNK Therapeutics, in patients with PD-1 refractory gastroesophageal cancer (GEC)—an area of significant unmet need where resistance to checkpoint inhibition remains a major clinical challenge.

Presentation Details:

Abstract Title: A phase II study of agenT-797, botensilimab (BOT) and balstilimab (BAL) in PD-1 refractory gastroesophageal cancer (GEC)

Presenter: Samuel L. Cytyrn, MD; Gastrointestinal Medical Oncologist, Memorial Sloan Kettering Cancer Center

Session Name: Phase II and Phase III Clinical Trials

Date/Time: April 20, 2026 | 2:00–5:00 PM PT; 5:00-8:00 PM EDT

Poster Section: 52

Abstract No.: CT166

(Press release, Agenus, APR 3, 2026, View Source [SID1234664170])