On June 16, 2026 Niowave, Inc., a leading manufacturer of medical radioisotopes, and Ratio Therapeutics Inc. (Ratio), a clinical-stage pharmaceutical company developing radiopharmaceuticals for cancer treatment, reported a supply agreement for Actinium-225.
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Under this agreement, Niowave will supply cGMP Actinium-225 to support Ratio’s development of targeted radiotherapeutics. The supply agreement provides Ratio with further reliable sourcing of Actinium-225 to support ongoing clinical trial activities and future program advancement.
Actinium-225 is a highly sought after alpha-emitting radioisotope with significant potential in targeted cancer therapies. When attached to targeting molecules, Actinium-225 delivers potent alpha radiation directly to cancer cells while minimizing damage to surrounding healthy tissue. As demand for targeted alpha therapies continues to grow, establishing a reliable domestic supply of Actinium-225 remains essential to clinical development and future commercialization.
"Niowave is the leading partner for companies with radiopharmaceutical programs that require a reliable, scalable supply of Actinium-225, and we are pleased to be working with Ratio," said Matt Burba, President and Chief Commercial Officer of Niowave. "Our agreement demonstrates the growing importance of medical radioisotopes, especially Actinium-225, and their potential to bring new hope to patients."
"Niowave’s expertise and growing production capabilities make them an important partner as we continue advancing our radiopharmaceutical pipeline," said John Babich, Ph.D., Chief Scientific Officer of Ratio Therapeutics. "This agreement supports our efforts to secure the Actinium-225 supply needed for ongoing clinical development while reinforcing our broader strategy of building the infrastructure and partnerships necessary to bring targeted alpha therapies to patients."
(Press release, Ratio Therapeutics, JUN 16, 2026, View Source [SID1234668762])