On October 13, 2026 TuHURA Biosciences, Inc. (NASDAQ:HURA) ("TuHURA" or the "Company"), a Phase 3 immuno-oncology company developing novel therapeutics to overcome resistance to cancer immunotherapy, reported that the United States Patent and Trademark Office (USPTO) has issued Patent No. 12,760,104 entitled, "Anti-VISTA Antibodies and Uses Thereof."
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
The new patent claims provide coverage for TBS-2025, TuHURA’s VISTA inhibiting antibody, as well as antigen-binding fragments, modifications to the frameworks and Fc regions of the antibody, and bi-specific/multi-specific antibodies across all classes of human antibodies. Additionally, the patent provides coverage for use as a single agent or in combination with radiotherapy, chemotherapy, targeted therapies, tyrosine kinase inhibitor therapies, and immune checkpoint inhibitors, including PD-1 inhibitors. The new patent claims also provide coverage for methods of treatment that extend beyond cancer, expanding into new treatment areas like autoimmune disease and infection. The patent term extends to February 18, 2042, prior to any potential patent term adjustment and/or regulatory patent term extension.
"VISTA is increasingly becoming a critical target for intervention not only in AML and MDS but also in multiple myeloma where emerging scientific data links VISTA to treatment failure and importantly to myeloma related bone destruction," said Dr. James Bianco, President and Chief Executive Officer of TuHURA. "Having patent protection for TBS-2025 across a wide array of new molecular modifications allows us to expand our approaches to blood related cancers and widen potential therapeutic applications, including into autoimmune diseases and infection. This is of extraordinary value in not only protecting our VISTA franchise, but also in making TBS-2025 even more valuable to potential future corporate collaborators."
(Press release, TuHURA Biosciences, OCT 13, 2026, View Source [SID1234673361])