On November 16, 2018 apceth Biopharma GmbH, an established contract manufacturing organization in the field of gene and cell therapy, reported it has started supplying clinical batches of DCprime’s cell-based cancer vaccine DCP-001 to a phase II clinical study for the treatment of Acute Myeloid Leukemia (AML) (Press release, apceth, NOV 16, 2018, View Source [SID1234531454]). AML is a haematological cancer characterized by high risk of relapse, even after initial response to chemotherapy. Cancer vaccination with dendritic cells could be a successful strategy to boost the patient’s immune system and result in lasting disease control. DCprime announced yesterday that the first patient has been treated with the product DCP-001 at the Amsterdam University Medical Center (UMC).

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"We are proud to be the manufacturing partner of DCprime for DCP-001, the first off-the shelf dendritic cell vaccine in a cancer indication with high unmet medical need", explained Dr Christine Günther, CEO of apceth Biopharma. "Our long-term collaboration with DCprime has always been constructive and cooperative, from technology transfer to the large-scale manufacturing process."

Dr Erik Manting, CEO of DCprime, commented: "Based on the recently published encouraging results of the phase I trial with our lead product DCP-001, we aim to confirm these results in the phase II ADVANCE-II trial and we are happy with the enrollment of the first patient. We would like to thank the apceth Biopharma team for their important contribution to the manufacturing of our product."