On January 29, 2019 Actinium Pharmaceuticals, Inc. (NYSE American: ATNM) ("Actinium" or "the Company") reported that it will host a key opinion leader (KOL) breakfast on targeted conditioning for bone marrow transplant (BMT) and CAR-T from 8:00 AM to 9:30 AM EST on Thursday, February 7th, in New York City (Press release, Actinium Pharmaceuticals, JAN 29, 2019, View Source [SID1234532940]).
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The event will feature a presentation by KOL Sergio Giralt, MD, Chief of Adult BMT, Memorial Sloan Kettering Cancer Center, who will discuss the potential of targeted conditioning with ARCs or Antibody Radiation-Conjugates in conjunction with BMT or Bone Marrow Transplant for patients ineligible or underserved by current conditioning regimens. Dr. Giralt’s presentation will highlight an initial safety and feasibility analysis of data from Actinium’s pivotal Iomab-B Phase 3 SIERRA trial, which were presented in an oral presentation at the 60th American Society of Hematology (ASH) (Free ASH Whitepaper) Annual Meeting in December 2018. Dr. Giralt will be available at the conclusion of the event to answer any questions from the audience.
In addition, members of the Actinium management team will discuss how the Company is applying its ARCs for targeted conditioning in patients prior to CAR-T with the goal of eliminating the need for chemotherapy conditioning regimens like Flu/Cy (Fludarabine and Cyclophosphamide). Finally, management will introduce their AWE or Antibody Warhead Enabling technology platform that has enabled combination trials with Venetoclax, a bio-better of J&J’s darzalex, and a research collaboration with Astellas Pharma, Inc.
This event is intended for institutional investors, sell-side analysts, and business development professionals only and they are requested to RSVP Click Here. For those who are unable to attend in person, a live webcast and replay will be accessible via the link Click Here.
About Dr. Sergio Giralt
Dr. Giralt, MD, Chief of Adult BMT, Memorial Sloan Kettering Cancer Center; Chair, Myeloma Service; and a board-certified hematologist/oncologist whose clinical practice and research focus on stem cell transplantation for patients with blood disorders. Previously, Dr. Giralt was Deputy Chair of the Department of Stem Cell Transplantation and Cellular Therapies at the University of Texas MD Anderson Cancer Center.
Dr. Giralt and his colleagues pioneered the use of reduced-intensity conditioning regimens for older or more debilitated patients with blood cancers, and are currently using and studying T cell depletion techniques to dramatically reduce the risk of graft-versus-host disease, a serious complication of donor stem cell transplantation. Dr. Giralt’s clinical and research activities include stem cell transplantation for patients with blood disorders and improving treatments for older patients who have acute and chronic leukemia. He has published and presented extensively on these topics. Additionally, Dr. Giralt has served as the principal investigator for a number of clinical trials that examine new treatment approaches for multiple myeloma and other blood cancers that aim to reduce symptom burden and improve treatment tolerability.
Dr. Giralt received his medical degree from Universidad Central de Venezuela. He completed his residency at Good Samaritan Hospital and his fellowship at The University of Texas MD Anderson Cancer Center. Dr. Giralt is Professor of Medicine at Weill Cornell Medical College and the Chief Attending Physician of the Adult Bone Marrow Transplant Service in the Department of Medicine at Memorial Sloan Kettering Cancer Center in New York City. In addition, he is the Melvin Berlin Family Chair in Myeloma Research.