Bioasis Announces Issuance of Japanese Patent Relating to xB3™ Platform Technology for The Delivery of Therapeutic Agents Across The Blood-Brain Barrier

On November 14, 2019 Bioasis Technologies Inc. (TSX.V:BTI; OTCQB:BIOAF) (the "Company" or "Bioasis"), a pre-clinical, research-stage biopharmaceutical company developing its proprietary xB3 platform technology for the delivery of therapeutics across the blood-brain barrier ("BBB") and the treatment of central nervous system ("CNS") disorders in areas of high unmet medical need, including brain cancers and neurodegenerative diseases, reported that the Japanese Patent Office ("JPO") issued Japanese Patent No. 6603227 for the Company’s platform technology (Press release, biOasis, NOV 14, 2019, View Source [SID1234551320]).

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The patent relates to Bioasis’ P97 conjugates with therapeutic agents where the P97 has the ability to transport the agent across the BBB. These conjugates include xB3-001, Bioasis’ lead product conjugate with trastuzumab in development for the treatment of HER2+ breast cancer brain metastases. The issued claims of this patent also cover pharmaceutical compositions containing the conjugates.

"We are excited about the issuance of this patent by the Japanese Patent Office, because it represents a major milestone for our intellectual property protection around our core assets in the Asian market, particularly the important Japanese market. Adding to the already granted patent in Europe, this further strengthens and reinforces our standing around our core technology and our priority program xB3-001," said Company Chair and Chief Executive Officer, Deborah Rathjen, Ph.D. "The Bioasis business model is based on the strength of these assets, the intellectual property that is protected by our broad patent portfolio."