On October 20, 2020 Aileron Therapeutics (Nasdaq: ALRN) reported that it will host a conference call and live webcast to discuss results from a Phase 1b proof-of-concept study of ALRN-6924 on Monday, October 26, 2020 at 8:30 a.m. ET (Press release, Aileron Therapeutics, OCT 20, 2020, http://investors.aileronrx.com/news-releases/news-release-details/aileron-therapeutics-host-conference-call-discuss-results-phase [SID1234568681]). As previously announced by Aileron, the Phase 1b clinical data will be presented in a late-breaking poster presentation during the upcoming 32nd EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) Annual (ENA 2020) Symposium on Molecular Targets and Cancer Therapeutics, being held virtually October 24 – 25, 2020. The abstract entitled, "Prevention of Chemotherapy-induced Myelosuppression in SCLC patients treated with the Dual MDM2/MDMX inhibitor ALRN-6924," (LBA96) will be presented starting Saturday, October 24 at 10:00 a.m. CEST (4:00 a.m. ET), on the ENA 2020 website.
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ALRN-6924 is the first and only chemoprotective therapy in clinical development to utilize a biomarker strategy by treating patients with p53-mutated cancers with the goal of limiting chemotherapy-induced toxicities and side effects. ALRN-6924, an investigational first-in-class MDM2/MDMX dual inhibitor, is a cell-permeating peptide drug that works intracellularly, activating wild-type p53 to selectively shield normal, healthy cells from chemotherapy in patients who harbor p53 mutations without interrupting chemotherapy’s targeting of cancer cells.
A live audio webcast of Aileron’s conference call will be available on the Investors section of Aileron’s website at View Source To access the call, please dial 877-705-6003 (domestic) or +1 201-493-6725 (international) five minutes prior to the start time and reference conference ID 13712133. The webcast will be archived on Aileron’s site for one year.