BeiGene Announces Data on BRUKINSA® (Zanubrutinib) and Tislelizumab to Be Presented at the 62nd ASH Annual Meeting

On November 5, 2020 BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160), a commercial-stage biotechnology company focused on developing and commercializing innovative medicines worldwide, reported that clinical data on its BTK inhibitor BRUKINSA (zanubrutinib) and non-clinical data on its anti-PD-1 antibody tislelizumab will be presented in an oral presentation and four posters at the 62nd American Society for Hematology (ASH) (Free ASH Whitepaper) Annual Meeting, taking place virtually on December 5-8, 2020 (Press release, BeiGene, NOV 5, 2020, View Source [SID1234570181]).

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BeiGene is co-sponsoring a satellite symposium entitled Addressing the Medical Need in CLL: How BTK Inhibitors Are Improving Outcomes, to be held on Friday, December 4 at 3:00 p.m. PT; registration for the symposium can be accessed at View Source

Oral Presentation:

Title:

Efficacy and Safety of Zanubrutinib in Patients with Relapsed/Refractory Marginal Zone Lymphoma: Initial Results of the MAGNOLIA (BGB-3111-214) Trial

Publication #:

339

Session Title:

623. Mantle Cell, Follicular, and Other Indolent B-Cell Lymphoma—Clinical Studies: Clinical studies in Waldenström’s Macroglobulinemia, Marginal Zone Lymphoma and Hairy Cell Leukemia

Date and Time:

Sunday, December 6, 2020 at 10:15 a.m. PT

Presenter:

Stephen Opat, FRACP, FRCPA, MBBS, Monash University, Australia

Poster Presentations:

Title:

Safety and Efficacy of the Bruton Tyrosine Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Waldenström Macroglobulinemia from a Phase 2 Trial

Publication #:

2940

Session Title:

623. Mantle Cell, Follicular, and Other Indolent B-Cell Lymphoma—Clinical Studies: Poster III

Date:

Monday, December 7, 2020 at 7:00 a.m. PT

Presenter:

Gang An, M.D., Ph.D., Chinese Academy of Medical Sciences, Blood Diseases Hospital, China

Title:

Phase 2 Study of Zanubrutinib in Patients with Relapsed/Refractory B-Cell Malignancies Intolerant to Ibrutinib/Acalabrutinib

Publication #:

2947

Session Title:

623. Mantle Cell, Follicular, and Other Indolent B-Cell Lymphoma—Clinical Studies: Poster III

Date:

Monday, December 7, 2020 at 7:00 a.m. PT

Presenter:

Mazyar Shadman, M.D., MPH, Fred Hutchinson Cancer Research Center, University of Washington

Title:

Efficacy and Safety of Zanubrutinib in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) with del(17p): Follow-up Results from Arm C of the SEQUOIA (BGB-3111-304) Trial

Publication #:

1306

Session Title:

642. CLL: Therapy, excluding Transplantation: Poster I

Date:

Saturday, December 5, 2020 at 7:00 a.m. PT

Presenter:

Jennifer R. Brown, M.D., Ph.D., Dana-Farber Cancer Institute

Title:

Tumor Microenvironment Associated with Complete Response to Tislelizumab Monotherapy in Relapsed/Refractory Classical Hodgkin Lymphoma Reveals a Potentially Different Mechanism of Action

Publication #:

1116

Session Title:

622. Lymphoma Biology—Non-Genetic Studies: Poster I

Date:

Saturday, December 5, 2020 at 7:00 a.m. PT

Presenter:

Yuqin Song, M.D., Ph.D., Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), China