On November 10, 2020 Xilio Therapeutics, a biotechnology company developing potent, tumor-selective immunotherapies for patients with cancer, reported the upcoming presentation of two abstracts featuring preclinical data related to its most advanced product candidates, XTX101 and XTX201 (Press release, Xilio Therapeutics, NOV 10, 2020, View Source [SID1234570553]). The data will be shared at the 35th Annual Meeting of The Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) (SITC 2020) taking place virtually November 9 – 14, 2020.

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The abstract featuring data on XTX201, Xilio’s tumor-selective IL-2, will be shared in a virtual poster viewing session. The abstract featuring data on the tumor-selective aCTLA4 antibody XTX101 will be shared in an oral presentation and in a virtual poster viewing session.

Details on Xilio’s abstracts are as follows:

Abstract #: 568
Abstract Title: XTX201, a protein-engineered IL-2, exhibits tumor-selective activity in mice without peripheral toxicities in non-human primates
Presenting Author: Minjie Zhang, PhD, Senior Scientist, In Vivo Pharmacology at Xilio Therapeutics
Virtual Poster Viewing Session: Thursday, November 12, from 4:50-5:20 p.m. EST and Saturday, November 14, from 1:00-1:30 p.m. EST

Abstract #: 587
Abstract Title: Tumor-activated Fc-engineered anti-CTLA-4 monoclonal antibody, XTX101, demonstrates tumor-selective PD and efficacy in preclinical models
Presenting Oral Presentation Author: Friday November 13, from 4:25-4:40 p.m. EST. Kurt Jenkins, PhD, Principal Scientist, Cell Pharmacology at Xilio Therapeutics
Oral Presentation: Wednesday, November 11, from 5:15-5:45 p.m. EST and Friday, November 13, from 4:40-5:10 p.m. EST
Presenting Poster Session Author: Parker Johnson, PhD, Senior Scientist, Structural Biology at Xilio Therapeutics
Virtual Presentation Viewing Session: Wednesday, November 11, from 5:15-5:45 p.m. EST and Friday, November 13, from 4:40-5:10 p.m. EST

Abstracts can be accessed on the SITC (Free SITC Whitepaper) website once the conference begins on November 9 at 8:00 a.m. EST.