On November 17, 2020 Puma Biotechnology, Inc. (Nasdaq: PBYI), a biopharmaceutical company, announced the release of 10 abstracts that will be presented at the 2020 Virtual San Antonio Breast Cancer Symposium (SABCS) from Dec 8-11, 2020 (Press release, Puma Biotechnology, NOV 17, 2020, View Source [SID1234571287]). Abstracts are available to the public online on the SABCS website at www.sabcs.org.
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Spotlight poster discussions are as follows:
PD1-05
Title: Latest findings from the breast cancer cohort in SUMMIT – a phase 2 ‘basket’ trial of neratinib + trastuzumab + fulvestrant for HER2-mutant, hormone receptor-positive, metastatic breast cancer
Presenter: Komal Jhaveri, M.D., Ph.D
Wednesday, Dec. 9, 4:00 – 5:15 p.m. CT
PD3-03
Title: Continued efficacy of neratinib in patients with HER2-positive early-stage breast cancer: Final overall survival analysis from the randomized phase 3 ExteNET trial
Presenter: Frankie Ann Holmes, M.D., FACP
Wednesday, Dec. 9, 6:30 – 7:45 p.m. CT
PD13-09
Title: Impact of neratinib on outcomes in HER2-positive metastatic breast cancer patients with central nervous system disease at baseline: Findings from the phase 3 NALA trial
Presenter: Cristina Saura, M.D., Ph.D.
Friday, Dec. 11, 1:00 – 2:15 p.m. CT
Additional posters to be presented on Wednesday, Dec. 9, beginning at 8:00 a.m. CT are as follows:
PS13-20
Title: Bringing diarrhea under CONTROL: dose escalation reduces neratinib-associated diarrhea and improves tolerability in HER2-positive early-stage breast cancer
Presenter: Manuel Ruiz-Borrego, M.D.
PS9-02
Title: Neratinib + capecitabine sustains health-related quality of life (HRQoL) while improving progression-free survival (PFS) in patients with HER2+ metastatic breast cancer and ≥2 prior HER2-directed regimens
Presenter: Beverly Moy, M.D., M.P.H.
PS7-61
Title: The Neat-HER Virtual Registry: Results on HER2+ breast cancer patients receiving neratinib as extended adjuvant therapy
Presenter: Hope Rugo, M.D.
PS10-45
Title: Budget impact of introducing neratinib for third-line treatment of HER2+ metastatic breast cancer in the United States
Presenter: Seri Anderson, Ph.D.
PS9-33
Title: Cost-effectiveness of neratinib for the extended adjuvant treatment of adult patients with early-stage, HR+, HER2-overexpressed/amplified breast cancer who initiated neratinib within 1 year of completing trastuzumab in the US
Presenter: Adam Brufsky, M.D,, Ph.D.
PS9-54
Title: Healthcare costs for metastatic breast cancer patients treated with human epidermal growth factor receptor 2 targeted agents
Presenter: Reshma Mahtani, D.O.
PS10-22
Title: Breast cancer mortality in women with HER2+ disease treated in a large integrated healthcare system
Presenter: Reina Haque, Ph.D., M.P.H.