On March 9, 2021 NanOlogy, LLC, a clinical-stage oncology company, reported that enrollment has been completed in its clinical trial of NanoDoce for bladder cancer (Press release, NanOlogy, MAR 9, 2021, View Source [SID1234576319]).

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Local bladder cancer at high risk for progression often requires removal of the bladder resulting in a severe lifelong quality of life issues. NanOlogy enrolled 36 bladder cancer patients in a Phase 1/2 two-arm trial evaluating direct injection/instillation of NanoDoce Suspension.

The first arm (n=19) included patients with high risk nonmuscle invasive bladder cancer. A high majority to date had a complete response at 3 months with 12 month data available in 2Q2021.

The second arm (n=17) included patients with muscle invasive bladder cancer. More than half have retained their bladder with no intervention at the initial study endpoint, now extended up to 12 months to test durability. These preliminary results will be updated and published once final.