On August 16, 2021 Lantern Pharma (NASDAQ: LTRN), a clinical stage biopharmaceutical company using its proprietary RADR artificial intelligence ("A.I.") platform to transform the cost, pace, and timeline of oncology drug discovery and development, reported that Lantern Pharma’s abstract titled ‘LP-184, a novel alkylating agent, is highly effective in pancreatic cancers with DNA damage repair defects‘ has been accepted as a virtual poster at the upcoming AACR (Free AACR Whitepaper) Virtual Special Conference on Pancreatic Cancer being held on September 29-30, 2021 (Press release, Lantern Pharma, AUG 16, 2021, View Source;utm_medium=rss&utm_campaign=abstract-on-effectiveness-of-lp-184-in-pancreatic-cancers [SID1234586631]).
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The abstract submitted by Lantern Pharma and researchers at Fox Chase Cancer Center describes work demonstrating promising efficacy of LP-184 in multiple in vitro and in vivo pancreatic cancer models. The abstract also highlights the increased efficacy and synthetic lethality of LP-184 in pancreatic cancers with DNA damage repair deficiencies.
Virtual posters will be available on-demand to attendees starting on September 29, 2021 and will remain accessible for 90 days after the live program ends. Accepted abstracts will be published as an online-only proceedings supplement to an AACR (Free AACR Whitepaper) journal after the completion of the meeting.
LP-184 is a small molecule drug candidate and next generation alkylating agent that preferentially damages DNA in cancer cells that over-express certain biomarkers or that harbor mutations in DNA repair pathways. LP-184 is being developed for several targeted indications in cancer, including pancreatic cancer. LP-184 has recently been granted Orphan Drug Designation by the U.S. Food and Drug Administration for the treatment of pancreatic cancer.