On October 21, 2021 Alligator Bioscience reported that First Patient Dosed in Optimize-1 Phase II (Press release, Alligator Bioscience, OCT 21, 2021, View Source [SID1234591743])
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"We continued to make great strides in the third quarter of 2021. The first patient was dosed in OPTIMIZE-1, our clinical Phase II study, that will assess the effect of mitazalimab in first line pancreatic cancer. We entered a collaboration with Finnish based Orion Corporation focusing on the discovery of novel immuno-oncology product candidates. With my first full quarter at the helm of this amazing company, I am even more confident in the potential value of our robust pipeline."
Søren Bregenholt
CEO Alligator Bioscience AB (publ)
Significant Events: July – September 2021
New Senior Director of Communications and Investor Relations, Julie Silber, joined the Company, bringing a unique experience from Wall Street and 20+ years of investor relations, strategic communications, counsel, and executive financial leadership.
The Company entered into a research collaboration and license agreement with Orion Corporation, a global pharmaceutical company based in Finland, to discover and develop new immuno-oncology product candidates.
The Company announced that it is exploring financing alternatives to support phase II studies for Mitazalimab, phase II preparations for ATOR-1017, as well as the development of other pipeline assets.
The Company announced positive results from our collaboration with Scandion Oncology (Sweden) exploring the anti-tumor efficacy of the CD40 antibody mitazalimab in chemotherapy-resistant preclinical tumor models as an addition to chemotherapy (FOLFIRINOX).
The Company announced first patient dosed in OPTIMIZE-1 Phase II clinical trial evaluating mitazalimab in combination with mFOLFIRINOX for the treatment of Pancreatic Cancer. OPTIMIZE-1 is an open-label, multicenter study that will enroll up to 67 patients at clinical sites in Belgium and France. The company is expecting an interim safety readout in Q1 2022 and an interim efficacy readout in Q4 2022.
Shanghai Henlius Biotech Inc. (China) reported that Alligator’s partner program AC101 had entered into Phase II clinical trial.
FINANCIAL SUMMARY
July-September 2021
Net sales, SEK 3.3 million (0.0)
Operating result, SEK -37.7 million (-30.6)
Result for the period, SEK -37.2 million (-30.8)
Earnings per share before and after dilution, SEK -0.43 (-0.43)
Cash flow for the period, SEK -30.4 million (-32.7)
Cash and cash equivalents, incl. interest-bearing securities, SEK 79.3 million (137.0)
January-September 2021
Net sales, SEK 7.7 million (4.4)
Operating result, SEK -104.7 million (-110.2)
Result for the period, SEK -104.9 million (-108.8)
Earnings per share before and after dilution, SEK -1.23 (-1.52)
Cash flow for the period, SEK -24.0 million (42.6)
The full report is attached as PDF available on the company’s website: View Source
Conference call/webcast
Alligator will host a conference call today, October 21, 2021, at 2:00 p.m. CEST for investors, analysts and media, where CEO Søren Bregenholt and CFO Marie Svensson will present and comment on the Interim Report. The conference call will be held in English.
The conference call will be broadcast live on the web via the link: View Source
Telephone number for the conference call is:
This information is such information as Alligator Bioscience AB (publ) is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact persons set out above, at 08:00 a.m. CEST on October 21, 2021.